- Analysis of the Binding Forces Driving the Tight Interactions between beta-Lactamase Inhibitory Protein-II (BLIP-II) and Class A beta-Lactamases
[作者：Brown, NG; Chow, DC; Sankaran, B; Zwart, P; Prasad, BVV; Palzkill, T,期刊：Journal of Biological Chemistry, 页码：32723-32735 , 文章类型： Article，,卷期：2011年286-37]
- beta-Lactamases hydrolyze beta-lactam antibiotics to provide drug resistance to bacteria. beta-Lactamase inhibitory protein-II (BLIP-II) is a potent proteinaceous inhibitor that exhibits low picomolar affinity for class ...
- A Novel Functional Role of Collagen Glycosylation INTERACTION WITH THE ENDOCYTIC COLLAGEN RECEPTOR uPARAP/ENDO180
[作者：Jurgensen, HJ; Madsen, DH; Ingvarsen, S; Melander, MC; Gardsvoll, H; Patthy, L; Engelholm, LH; Behrendt, N,期刊：Journal of Biological Chemistry, 页码：32736-32748 , 文章类型： Article，,卷期：2011年286-37]
- Collagens make up the most abundant component of interstitial extracellular matrices and basement membranes. Collagen remodeling is a crucial process in many normal physiological events and in several pathological condit...
- Regulation of Catch Bonds by Rate of Force Application
[作者：Sarangapani, KK; Qian, J; Chen, W; Zarnitsyna, VI; Mehta, P; Yago, T; McEver, RP; Zhu, C,期刊：Journal of Biological Chemistry, 页码：32749-32761 , 文章类型： Article，,卷期：2011年286-37]
- The current paradigm for receptor-ligand dissociation kinetics assumes off-rates as functions of instantaneous force without impact from its prior history. This a priori assumption is the foundation for predicting dissoc...
- Distinct Involvement of the Gab1 and Grb2 Adaptor Proteins in Signal Transduction by the Related Receptor Tyrosine Kinases RON and MET
[作者：Chaudhuri, A; Xie, MH; Yang, B; Mahapatra, K; Liu, JF; Marsters, S; Bodepudi, S; Ashkenazi, A,期刊：Journal of Biological Chemistry, 页码：32762-32774 , 文章类型： Article，,卷期：2011年286-37]
- Although the signal transduction mechanisms of the receptor tyrosine kinase MET are well defined, less is known about its close relative RON. MET initiates intracellular signaling by autophosphorylation on specific cytop...
- Histone Deacetylase (HDAC) Activity Is Critical for Embryonic Kidney Gene Expression, Growth, and Differentiation
[作者：Chen, SW; Bellew, C; Yao, X; Stefkova, J; Dipp, S; Saifudeen, Z; Bachvarov, D; El-Dahr, SS,期刊：Journal of Biological Chemistry, 页码：32775-32789 , 文章类型： Article，,卷期：2011年286-37]
- Histone deacetylases (HDACs) regulate fundamental biological processes such as cellular proliferation, differentiation, and survival via genomic and nongenomic effects. This study examined the importance of HDAC activity...
- Adiponectin Ameliorates Doxorubicin-induced Cardiotoxicity through Akt Protein-dependent Mechanism
[作者：Maruyama, S; Shibata, R; Ohashi, K; Ohashi, T; Daida, H; Walsh, K; Murohara, T; Ouchi, N,期刊：Journal of Biological Chemistry, 页码：32790-32800 , 文章类型： Article，,卷期：2011年286-37]
- Accumulating evidence shows that obesity is associated with doxorubicin cardiac toxicity in the heart, but the molecular mechanisms that contribute to this pathological response are not understood. Adiponectin is an adip...
- Small Angle Neutron Scattering Reveals pH-dependent Conformational Changes in Trichoderma reesei Cellobiohydrolase I IMPLICATIONS FOR ENZYMATIC ACTIVITY
[作者：Pingali, SV; O'Neill, HM; McGaughey, J; Urban, VS; Rempe, CS; Petridis, L; Smith, JC; Evans, BR; Heller, WT,期刊：Journal of Biological Chemistry, 页码：32801-32809 , 文章类型： Article，,卷期：2011年286-37]
- Cellobiohydrolase I (Cel7A) of the fungus Trichoderma reesei (now classified as an anamorph of Hypocrea jecorina) hydrolyzes crystalline cellulose to soluble sugars, making it of key interest for producing fermentable su...
- Classical and Neonatal Marfan Syndrome Mutations in Fibrillin-1 Cause Differential Protease Susceptibilities and Protein Function
[作者：Kirschner, R; Hubmacher, D; Iyengar, G; Kaur, J; Fagotto-Kaufmann, C; Bromme, D; Bartels, R; Reinhardt, DP,期刊：Journal of Biological Chemistry, 页码：32810-32823 , 文章类型： Article，,卷期：2011年286-37]
- Mutations in fibrillin-1 give rise to Marfan syndrome (MFS) characterized by vascular, skeletal, and ocular abnormalities. Fibrillins form the backbone of extracellular matrix microfibrils in tissues including blood vess...
- HNK-1 Glycan Functions as a Tumor Suppressor for Astrocytic Tumor
[作者：Suzuki-Anekoji, M; Suzuki, M; Kobayashi, T; Sato, Y; Nakayama, J; Suzuki, A; Bao, XF; Angata, K; Fukuda, M,期刊：Journal of Biological Chemistry, 页码：32824-32833 , 文章类型： Article，,卷期：2011年286-37]
- Astrocytic tumor is the most prevalent primary brain tumor. However, the role of cell surface carbohydrates in astrocytic tumor invasion is not known. In a previous study, we showed that polysialic acid facilitates astro...
- Comparative Analysis of Histophilus somni Immunoglobulin-binding Protein A (IbpA) with Other Fic Domain-containing Enzymes Reveals Differences in Substrate and Nucleotide Specificities
[作者：Mattoo, S; Durrant, E; Chen, MJ; Xiao, JY; Lazar, CS; Manning, G; Dixon, JE; Worby, CA,期刊：Journal of Biological Chemistry, 页码：32834-32842 , 文章类型： Article，,卷期：2011年286-37]
- A new family of adenylyltransferases, defined by the presence of a Fic domain, was recently discovered to catalyze the addition of adenosine monophosphate (AMP) to Rho GTPases (Yarbrough, M. L., Li, Y., Kinch, L. N., Gri...
- Metabolic Alterations in Highly Tumorigenic Glioblastoma Cells PREFERENCE FOR HYPOXIA AND HIGH DEPENDENCY ON GLYCOLYSIS
[作者：Zhou, YF; Zhou, Y; Shingu, T; Feng, L; Chen, Z; Ogasawara, M; Keating, MJ; Kondo, S; Huang, P,期刊：Journal of Biological Chemistry, 页码：32843-32853 , 文章类型： Article，,卷期：2011年286-37]
- Recent studies suggest that a small subpopulation of malignant cells with stem-like properties is resistant to chemotherapy and may be responsible for the existence of residual cancer after treatment. We have isolated hi...
- Neutrophil beta(2) Integrin Inhibition by Enhanced Interactions of Vasodilator-stimulated Phosphoprotein with S-Nitrosylated Actin
[作者：Thom, SR; Bhopale, VM; Yang, M; Bogush, M; Huang, SH; Milovanova, TN,期刊：Journal of Biological Chemistry, 页码：32854-32865 , 文章类型： Article，,卷期：2011年286-37]
- Production of reactive species in neutrophils exposed to hyperoxia causes S-nitrosylation of beta-actin, which increases formation of short actin filaments, leading to alterations in the cytoskeletal network that inhibit...
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