- Total Synthesis of (-)-CP(2)-Disorazole C(1)
[作者:HOPKINS CHAD D; SCHMITZ JOHN C; CHU EDWARD; WIPR PETER,期刊:Organic Letters, 页码:4088-4091 , 文章类型: Article,,卷期:2011年13-15]
- The total synthesis of a bis-cyclopropane analog of the antimitotic natural product (-)-disorazole C(1) was accomplished in 23 steps and 1.1% overall yield. A vinyl cyclopropane cross-metathesis reaction generated a key ...
- On the Elucidation of the Mechanism of Vinca Alkaloid Fluorination in Superacidic Medium
[作者:GIOVANELLI EMERSON; LEROUX SEBASTIEN; MOISAN LIONEL; CARREYRE HELENE; THUERY PIERRE; BUISSON DAVIDALEXANDRE; MEDDOUR ABDELKRIM; COUSTARD JEANMARIE; THIBAUDEAU SEBASTIEN; ROUSSEAU BERNARD; NICOLAS MARC; HELLIER PAUL; DORIS ERIC,期刊:Organic Letters, 页码:4116-4119 , 文章类型: Article,,卷期:2011年13-15]
- Detailed investigations on one of the key steps of the superacidic fluorination of Vinca alkaloids that is the origin of C20' activation are reported. While two different pathways can be envisioned for the emergence of t...
- Fluoroanalogs of DDT: Superacidic BF(3)-H(2)O Catalyzed Facile Synthesis of 1,1,1-Trifluoro-2,2-diarylethanes and 1,1-Difluoro-2,2-diarylethanes
[作者:PRAKASH G K SURYA; PAKNIA FARZANEH; MATHEW THOMAS; MLOSTON GZREGORZ; JOSCHEK JENS P; OLAH GEORGE A,期刊:Organic Letters, 页码:4128-4131 , 文章类型: Article,,卷期:2011年13-15]
- The one-pot synthesis of 1,1,1-trifluoro- and 1,1-difluoro-2,2-diarylethanes from arenes and fluorinated hemiacetals in the BF(3)-H(2)O system is described. The reaction is simple, clean, and convenient, eliminating the ...
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