- Hyperthermia-induced Hsp90.eNOS Preserves Mitochondrial Respiration in Hyperglycemic Endothelial Cells by Down-regulating Glut-1 and Up-regulating G6PD Activity
[作者:Presley, T; Vedam, K; Druhan, LJ; Ilangovan, G,期刊:Journal of Biological Chemistry, 页码:38194-38203 , 文章类型: Article,,卷期:2010年285-49]
- Uncoupling of NO production from NADPH oxidation by endothelial nitric-oxide synthase (eNOS) is enhanced in hyperglycemic endothelium, potentially due to dissociation of heat shock proteins 90 (Hsp90), and cellular gluco...
- Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation
[作者:Kulkarni, MV; Tettamanzi, MC; Murphy, JW; Keeler, C; Myszka, DG; Chayen, NE; Lolis, EJ; Hodsdon, ME,期刊:Journal of Biological Chemistry, 页码:38524-38533 , 文章类型: Article,,卷期:2010年285-49]
- Human prolactin (hPRL), a member of the family of hematopoietic cytokines, functions as both an endocrine hormone and autocrine/paracrine growth factor. We have previously demonstrated that recognition of the hPRL.recept...
- The ATM Cofactor ATMIN Protects against Oxidative Stress and Accumulation of DNA Damage in the Aging Brain
[作者:Kanu, N; Penicud, K; Hristova, M; Wong, B; Irvine, E; Plattner, F; Raivich, G; Behrens, A,期刊:Journal of Biological Chemistry, 页码:38534-38542 , 文章类型: Article,,卷期:2010年285-49]
- Progressive accumulation of DNA damage is causally involved in cellular senescence and organismal aging. The DNA damage kinase ATM plays a central role in maintaining genomic stability. ATM mutations cause the genetic di...
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