- Intramembrane Proteolysis by gamma-Secretase
[作者:Steiner, H; Fluhrer, R; Haass, C,期刊:Journal of Biological Chemistry, 页码:29627-29631 , 文章类型: Review,,卷期:2008年283-44]
- gamma-Secretase mediates the final proteolytic cleavage, which liberates amyloid beta-peptide (A beta), the major component of senile plaques in the brains of Alzheimer disease patients. Therefore, gamma-secretase is a p...
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