- The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans
[作者:Shi, Z; Ruvkun, G,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4568-4573 , 文章类型: Article,,卷期:2012年109-12]
- The mevalonate pathway is highly conserved and mediates the production of isoprenoids, which feed into biosynthetic pathways for sterols, dolichol, ubiquinone, heme, isopentenyl adenine, and prenylated proteins. We found...
- Genetic dating indicates that the Asian-Papuan admixture through Eastern Indonesia corresponds to the Austronesian expansion
[作者:Xu, SH; Pugach, I; Stoneking, M; Kayser, M; Jin, L,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4574-4579 , 文章类型: Article,,卷期:2012年109-12]
- Although the Austronesian expansion had a major impact on the languages of Island Southeast Asia, controversy still exists over the genetic impact of this expansion. The coexistence of both Asian and Papuan genetic ances...
- Promiscuous binding of extracellular peptides to cell surface class I MHC protein
[作者:Eisen, HN; Hou, XH; Shen, C; Wang, KD; Tanguturi, VK; Smith, C; Kozyrytska, K; Nambiar, L; McKinley, CA; Chen, JZ; Cohen, RJ,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4580-4585 , 文章类型: Article,,卷期:2012年109-12]
- Algorithms derived from measurements of short-peptide (8-10 mers) binding to class I MHC proteins suggest that the binding groove of a class I MHC protein, such as K-b, can bind well over 1 million different peptides wit...
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