- Functional Extension of Amino Acid Triads from the Fourth Transmembrane Segment (S4) into Its External Linker in Shaker K(+) Channels
[作者：Yang, YC; Lin, S; Chang, PC; Lin, HC; Kuo, CC,期刊：Journal of Biological Chemistry, 页码：37503-37514 , 文章类型： Article，,卷期：2011年286-43]
- The highly conserved fourth transmembrane segment (S4) is the primary voltage sensor of the voltage-dependent channel and would move outward upon membrane depolarization. S4 comprises repetitive amino acid triads, each c...
- Identification of Self-lipids Presented by CD1c and CD1d Proteins
[作者：Haig, NA; Guan, ZQ; Li, DM; McMichael, A; Raetz, CRH; Xu, XN,期刊：Journal of Biological Chemistry, 页码：37692-37701 , 文章类型： Article，,卷期：2011年286-43]
- The CD1 family consists of five proteins that are related to the peptide-presenting MHC class I family. T cells can recognize the presentation of both foreign and self-derived lipids on four CD1 family members. The ident...
- Molecular Basis of the gamma-Aminobutyric Acid A Receptor alpha 3 Subunit Interaction with the Clustering Protein Gephyrin
[作者：Tretter, V; Kerschner, B; Milenkovic, I; Ramsden, SL; Ramerstorfer, J; Saiepour, L; Maric, HM; Moss, SJ; Schindelin, H; Harvey, RJ; Sieghart, W; Harvey, K,期刊：Journal of Biological Chemistry, 页码：37702-37711 , 文章类型： Article，,卷期：2011年286-43]
- The multifunctional scaffolding protein gephyrin is a key player in the formation of the postsynaptic scaffold at inhibitory synapses, clustering both inhibitory glycine receptors (GlyRs) and selected GABA(A) receptor (G...
- Caenorhabditis elegans UCP4 Protein Controls Complex II-mediated Oxidative Phosphorylation through Succinate Transport
[作者：Pfeiffer, M; Kayzer, EB; Yang, XM; Abramson, E; Kenaston, MA; Lago, CU; Lo, HH; Sedensky, MM; Lunceford, A; Clarke, CF; Wu, SJ; McLeod, C; Finkel, T; Morgan, PG; Mills, EM,期刊：Journal of Biological Chemistry, 页码：37712-37720 , 文章类型： Article，,卷期：2011年286-43]
- The novel uncoupling proteins (UCP2-5) are implicated in the mitochondrial control of oxidant production, insulin signaling, and aging. Attempts to understand their functions have been complicated by overlapping expressi...
- Mucopolysaccharidosis Type I, Unique Structure of Accumulated Heparan Sulfate and Increased N-Sulfotransferase Activity in Mice Lacking alpha-L-iduronidase
[作者：Holley, RJ; Deligny, A; Wei, W; Watson, HA; Ninonuevo, MR; Dagalv, A; Leary, JA; Bigger, BW; Kjellen, L; Merry, CLR,期刊：Journal of Biological Chemistry, 页码：37515-37524 , 文章类型： Article，,卷期：2011年286-43]
- Mucopolysaccharide (MPS) diseases are characterized by accumulation of glycosaminoglycans (GAGs) due to deficiencies in lysosomal enzymes responsible for GAG breakdown. Using a murine model of MPSI Hurler (MPSIH), we hav...
- Solution Structure of the Soluble Receptor for Advanced Glycation End Products (sRAGE)
[作者：Sarkany, Z; Ikonen, TP; Ferreira-da-Silva, F; Saraiva, MJ; Svergun, D; Damas, AM,期刊：Journal of Biological Chemistry, 页码：37525-37534 , 文章类型： Article，,卷期：2011年286-43]
- The receptor for advanced glycation end products (RAGE) is a multiligand cell surface receptor involved in various human diseases, as it binds to numerous molecules and proteins that modulate the activity of other protei...
- Transcription Factor Zic2 Inhibits Wnt/beta-Catenin Protein Signaling
[作者：Pourebrahim, R; Houtmeyers, R; Ghogomu, S; Janssens, S; Thelie, A; Tran, HT; Langenberg, T; Vleminckx, K; Bellefroid, E; Cassiman, JJ; Tejpar, S,期刊：Journal of Biological Chemistry, 页码：37732-37740 , 文章类型： Article，,卷期：2011年286-43]
- The Zic transcription factors play critical roles during embryonic development. Mutations in the ZIC2 gene are associated with human holoprosencephaly, but the etiology is still unclear. Here, we report a novel function ...
- Sources of Cell-to-cell Variability in Canonical Nuclear Factor-kappa B (NF-kappa B) Signaling Pathway Inferred from Single Cell Dynamic Images
[作者：Kalita, MK; Sargsyan, K; Tian, B; Paulucci-Holthauzen, A; Najm, HN; Debusschere, BJ; Brasier, AR,期刊：Journal of Biological Chemistry, 页码：37741-37757 , 文章类型： Article，,卷期：2011年286-43]
- The canonical nuclear factor-kappa B (NF-kappa B) signaling pathway controls a gene network important in the cellular inflammatory response. Upon activation, NF-kappa B/RelA is released from cytoplasmic inhibitors, from ...
- Cartilage Intermediate Layer Protein 2 (CILP-2) Is Expressed in Articular and Meniscal Cartilage and Down-regulated in Experimental Osteoarthritis
[作者：Bernardo, BC; Belluoccio, D; Rowley, L; Little, CB; Hansen, U; Bateman, JF,期刊：Journal of Biological Chemistry, 页码：37758-37767 , 文章类型： Article，,卷期：2011年286-43]
- Using transcriptome profiling to determine differential gene expression between the permanent mouse articular cartilage and the transient growth plate cartilage, we identified a highly expressed gene, Cilp2, which is exp...
- Oligomerization and Pore Formation by Equinatoxin II Inhibit Endocytosis and Lead to Plasma Membrane Reorganization
[作者：Garcia-Saez, AJ; Buschhorn, SB; Keller, H; Anderluh, G; Simons, K; Schwille, P,期刊：Journal of Biological Chemistry, 页码：37768-37777 , 文章类型： Article，,卷期：2011年286-43]
- Pore-forming toxins have evolved to induce membrane injury by formation of pores in the target cell that alter ion homeostasis and lead to cell death. Many pore-forming toxins use cholesterol, sphingolipids, or other raf...
- Allosteric and Orthosteric Sites in CC Chemokine Receptor (CCR5), a Chimeric Receptor Approach
[作者：Thiele, S; Steen, A; Jensen, PC; Mokrosinski, J; Frimurer, TM; Rosenkilde, MM,期刊：Journal of Biological Chemistry, 页码：37543-37554 , 文章类型： Article，,卷期：2011年286-43]
- Chemokine receptors play a major role in immune system regulation and have consequently been targets for drug development leading to the discovery of several small molecule antagonists. Given the large size and predomina...
- The Minimal Active Structure of Human Relaxin-2
[作者：Hossain, MA; Rosengren, KJ; Samuel, CS; Shabanpoor, F; Chan, LJ; Bathgate, RAD; Wade, JD,期刊：Journal of Biological Chemistry, 页码：37555-37565 , 文章类型： Article，,卷期：2011年286-43]
- H2 relaxin is a peptide hormone associated with a number of therapeutically relevant physiological effects, including regulation of collagen metabolism and multiple vascular control pathways. It is currently in phase III...
- Assembly Mechanism of FCT Region Type 1 Pili in Serotype M6 Streptococcus pyogenes
[作者：Nakata, M; Kimura, KR; Sumitomo, T; Wada, S; Sugauchi, A; Oiki, E; Higashino, M; Kreikemeyer, B; Podbielski, A; Okahashi, N; Hamada, S; Isoda, R; Terao, Y; Kawabata, S,期刊：Journal of Biological Chemistry, 页码：37566-37577 , 文章类型： Article，,卷期：2011年286-43]
- The human pathogen Streptococcus pyogenes produces diverse pili depending on the serotype. We investigated the assembly mechanism of FCT type 1 pili in a serotype M6 strain. The pili were found to be assembled from two p...
- Role of the Endoplasmic Reticulum-associated Degradation (ERAD) Pathway in Degradation of Hepatitis C Virus Envelope Proteins and Production of Virus Particles
[作者：Saeed, M; Suzuki, R; Watanabe, N; Masaki, T; Tomonaga, M; Muhammad, A; Kato, T; Matsuura, Y; Watanabe, H; Wakita, T; Suzuki, T,期刊：Journal of Biological Chemistry, 页码：37264-37273 , 文章类型： Article，,卷期：2011年286-43]
- Viral infections frequently cause endoplasmic reticulum (ER) stress in host cells leading to stimulation of the ER-associated degradation (ERAD) pathway, which subsequently targets unassembled glycoproteins for ubiquityl...
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