- Structural Characterization of Hsp12, the Heat Shock Protein from Saccharomyces cerevisiae, in Aqueous Solution Where It Is Intrinsically Disordered and in Detergent Micelles Where It Is Locally alpha-Helical
[作者:Singarapu, KK; Tonelli, M; Chow, DC; Frederick, RO; Westler, WM; Markley, JL,期刊:Journal of Biological Chemistry, 页码:43447-43453 , 文章类型: Article,,卷期:2011年286-50]
- Hsp12 (heat shock protein 12) belongs to the small heat shock protein family, partially characterized as a stress response, stationary phase entry, late embryonic abundant-like protein located at the plasma membrane to p...
- GRAIL (Gene Related to Anergy in Lymphocytes) Regulates Cytoskeletal Reorganization through Ubiquitination and Degradation of Arp2/3 Subunit 5 and Coronin 1A
[作者:Ichikawa, D; Mizuno, M; Yamamura, T; Miyake, S,期刊:Journal of Biological Chemistry, 页码:43465-43474 , 文章类型: Article,,卷期:2011年286-50]
- Anergy is an important mechanism for the maintenance of peripheral tolerance and avoidance of autoimmunity. The upregulation of E3 ubiqitin ligases, including GRAIL (gene related to anergy in lymphocytes), is a key event...
- Close-up of the Immunogenic alpha 1,3-Galactose Epitope as Defined by a Monoclonal Chimeric Immunoglobulin E and Human Serum Using Saturation Transfer Difference (STD) NMR
[作者:Plum, M; Michel, Y; Wallach, K; Raiber, T; Blank, S; Bantleon, FI; Diethers, A; Greunke, K; Braren, I; Hackl, T; Meyer, B; Spillner, E,期刊:Journal of Biological Chemistry, 页码:43103-43111 , 文章类型: Article,,卷期:2011年286-50]
- Anaphylaxis mediated by carbohydrate structures is a controversially discussed phenomenon. Nevertheless, IgE with specificity for the xenotransplantation antigen alpha 1,3-Gal (alpha-Gal) are associated with a delayed ty...
- Peroxisome Proliferator-activated Receptor alpha (PPAR alpha) Induces PPAR gamma Coactivator 1 alpha (PGC-1 alpha) Gene Expression and Contributes to Thermogenic Activation of Brown Fat INVOLVEMENT OF PRDM16
[作者:Hondares, E; Rosell, M; Diaz-Delfin, J; Olmos, Y; Monsalve, M; Iglesias, R; Villarroya, F; Giralt, M,期刊:Journal of Biological Chemistry, 页码:43112-43122 , 文章类型: Article,,卷期:2011年286-50]
- Peroxisome proliferator activated receptor alpha (PPAR alpha) is a distinctive marker of the brown fat phenotype that has been proposed to coordinate the transcriptional activation of genes for lipid oxidation and for th...
- GDP-mannose-4,6-dehydratase (GMDS) Deficiency Renders Colon Cancer Cells Resistant to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Receptor- and CD95-mediated Apoptosis by Inhibiting Complex II Formation
[作者:Moriwaki, K; Shinzaki, S; Miyoshi, E,期刊:Journal of Biological Chemistry, 页码:43123-43133 , 文章类型: Article,,卷期:2011年286-50]
- Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis through binding to TRAIL receptors, death receptor 4 (DR4), and DR5. TRAIL has potential therapeutic value against cancer because of its s...
- Novel Mechanism of RNA Repair by RtcB via Sequential 2 ',3 '-Cyclic Phosphodiesterase and 3 '-Phosphate/5 '-Hydroxyl Ligation Reactions
[作者:Tanaka, N; Chakravarty, AK; Maughan, B; Shuman, S,期刊:Journal of Biological Chemistry, 页码:43134-43143 , 文章类型: Article,,卷期:2011年286-50]
- RtcB enzymes are a newly discovered family of RNA ligases, implicated in tRNA splicing and other RNA repair reactions, that seal broken RNAs with 2',3'-cyclic phosphate and 5'-OH ends. Parsimony and energetics would sugg...
- Small-angle X-ray Scattering Studies of the Oligomeric State and Quaternary Structure of the Trifunctional Proline Utilization A (PutA) Flavoprotein from Escherichia coli
[作者:Singh, RK; Larson, JD; Zhu, WD; Rambo, RP; Hura, GL; Becker, DF; Tanner, JJ,期刊:Journal of Biological Chemistry, 页码:43144-43153 , 文章类型: Article,,卷期:2011年286-50]
- The trifunctional flavoprotein proline utilization A (PutA) links metabolism and gene regulation in Gram-negative bacteria by catalyzing the two-step oxidation of proline to glutamate and repressing transcription of the ...
- VIP36 Protein Is a Target of Ectodomain Shedding and Regulates Phagocytosis in Macrophage Raw 264.7 Cells
[作者:Shirakabe, K; Hattori, S; Seiki, M; Koyasu, S; Okada, Y,期刊:Journal of Biological Chemistry, 页码:43154-43163 , 文章类型: Article,,卷期:2011年286-50]
- Ectodomain shedding is a posttranslational modification mechanism, which liberates extracellular domains of membrane proteins through juxtamembrane processing executed mainly by the ADAM (a disintegrin and metalloproteas...
- Association of Plasminogen Activator Inhibitor Type 2 (PAI-2) with Proteasome within Endothelial Cells Activated with Inflammatory Stimuli
[作者:Boncela, J; Przygodzka, P; Papiewska-Pajak, I; Wyroba, E; Cierniewski, CS,期刊:Journal of Biological Chemistry, 页码:43164-43171 , 文章类型: Article,,卷期:2011年286-50]
- Quiescent endothelial cells contain low concentrations of plasminogen activator inhibitor type 2 (PAI-2). However, its synthesis can be rapidly stimulated by a variety of inflammatory mediators. In this study, we provide...
- Picomolar Nitric Oxide Signals from Central Neurons Recorded Using Ultrasensitive Detector Cells
[作者:Wood, KC; Batchelor, AM; Bartus, K; Harris, KL; Garthwaite, G; Vernon, J; Garthwaite, J,期刊:Journal of Biological Chemistry, 页码:43172-43181 , 文章类型: Article,,卷期:2011年286-50]
- Nitric oxide (NO) is a widespread signaling molecule with potentially multifarious actions of relevance to health and disease. A fundamental determinant of how it acts is its concentration, but there remains a lack of co...
- Regulation of Oocyte and Cumulus Cell Interactions by Intermedin/Adrenomedullin 2
[作者:Chang, CL; Wang, HS; Soong, YK; Huang, SY; Pai, SY; Hsu, SYT,期刊:Journal of Biological Chemistry, 页码:43193-43203 , 文章类型: Article,,卷期:2011年286-50]
- Ovarian folliculogenesis has been studied as a model of hormonal regulation of development and differentiation, cell death, and cell-cell communication. In addition to gonadotropins from the pituitary and follicular para...
- Tumor Protein p63/Nuclear Factor kappa B Feedback Loop in Regulation of Cell Death
[作者:Sen, T; Sen, N; Huang, YP; Sinha, D; Luo, ZG; Ratovitski, EA; Sidransky, D,期刊:Journal of Biological Chemistry, 页码:43204-43213 , 文章类型: Article,,卷期:2011年286-50]
- Tumor protein (TP)-p53 family members often play proapoptotic roles, whereas nuclear factor kappa B (NF-kappa B) functions as a proapoptotic and antiapoptotic regulator depending on the cellular environment. We previousl...
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