- Severe Neurologic Impairment in Mice with Targeted Disruption of the Electrogenic Sodium Bicarbonate Cotransporter NBCe2 (Slc4a5 Gene)
[作者：Kao, LY; Kurtz, LM; Shao, XS; Papadopoulos, MC; Liu, L; Bok, D; Nusinowitz, S; Chen, B; Stella, SL; Andre, M; Weinreb, J; Luong, SS; Piri, N; Kwong, JMK; Newman, D; Kurtz, I,期刊：Journal of Biological Chemistry, 页码：32563-32574 , 文章类型： Article，,卷期：2011年286-37]
- The choroid plexus lining the four ventricles in the brain is where the majority of cerebrospinal fluid (CSF) is produced. The secretory function of the choroid plexus is mediated by specific transport systems that allow...
- Physical and Functional Antagonism between Tumor Suppressor Protein p53 and Fortilin, an Anti-apoptotic Protein
[作者：Chen, YJ; Fujita, T; Zhang, D; Doan, H; Pinkaew, D; Liu, ZH; Wu, JX; Koide, Y; Chiu, A; Lin, CCJ; Chang, JY; Ruan, KH; Fujise, K,期刊：Journal of Biological Chemistry, 页码：32575-32585 , 文章类型： Article，,卷期：2011年286-37]
- Tumor suppressor protein p53, our most critical defense against tumorigenesis, can be made powerless by mechanisms such as mutations and inhibitors. Fortilin, a 172-amino acid polypeptide with potent anti-apoptotic activ...
- Improvement of a Potential Anthrax Therapeutic by Computational Protein Design
[作者：Wu, SJ; Eiben, CB; Carra, JH; Huang, I; Zong, D; Liu, PX; Wu, CT; Nivala, J; Dunbar, J; Huber, T; Senft, J; Schokman, R; Smith, MD; Mills, JH; Friedlander, AM; Baker, D; Siegel, JB,期刊：Journal of Biological Chemistry, 页码：32586-32592 , 文章类型： Article，,卷期：2011年286-37]
- Past anthrax attacks in the United States have highlighted the need for improved measures against bioweapons. The virulence of anthrax stems from the shielding properties of the Bacillus anthracis poly-gamma-D-glutamic a...
- LytN, a Murein Hydrolase in the Cross-wall Compartment of Staphylococcus aureus, Is Involved in Proper Bacterial Growth and Envelope Assembly
[作者：Frankel, MB; Hendrickx, APA; Missiakas, DM; Schneewind, O,期刊：Journal of Biological Chemistry, 页码：32593-32605 , 文章类型： Article，,卷期：2011年286-37]
- Cell cycle progression for the spherical microbe Staphylococcus aureus requires the coordinated synthesis and remodeling of peptidoglycan. The majority of these rearrangements takes place at the mid-cell, in a compartmen...
- The Atypical Response Regulator Protein ChxR Has Structural Characteristics and Dimer Interface Interactions That Are Unique within the OmpR/PhoB Subfamily
[作者：Hickey, JM; Lovell, S; Battaile, KP; Hu, L; Middaugh, CR; Hefty, PS,期刊：Journal of Biological Chemistry, 页码：32606-32616 , 文章类型： Article，,卷期：2011年286-37]
- Typically as a result of phosphorylation, OmpR/PhoB response regulators form homodimers through a receiver domain as an integral step in transcriptional activation. Phosphorylation stabilizes the ionic and hydrophobic in...
- Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway
[作者：Hodson, C; Cole, AR; Lewis, LPC; Miles, JA; Purkiss, A; Walden, H,期刊：Journal of Biological Chemistry, 页码：32628-32637 , 文章类型： Article，,卷期：2011年286-37]
- The Fanconi anemia (FA) pathway is essential for the repair of DNA interstrand cross-links. At the heart of this pathway is the monoubiquitination of the FANCI-FANCD2 (ID) complex by the multiprotein "core complex" conta...
- XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair
[作者：Hammel, M; Rey, M; Yu, YP; Mani, RS; Classen, S; Liu, M; Pique, ME; Fang, SJ; Mahaney, BL; Weinfeld, M; Schriemer, DC; Lees-Miller, SP; Tainer, JA,期刊：Journal of Biological Chemistry, 页码：32638-32650 , 文章类型： Article，,卷期：2011年286-37]
- The XRCC4-like factor (XLF)-XRCC4 complex is essential for nonhomologous end joining, the major repair pathway for DNA double strand breaks in human cells. Yet, how XLF binds XRCC4 and impacts nonhomologous end joining f...
- Redox Regulates Mammalian Target of Rapamycin Complex 1 (mTORC1) Activity by Modulating the TSC1/TSC2-Rheb GTPase Pathway
[作者：Yoshida, S; Hong, SK; Suzuki, T; Nada, S; Mannan, AM; Wang, JY; Okada, M; Guan, KL; Inoki, K,期刊：Journal of Biological Chemistry, 页码：32651-32660 , 文章类型： Article，,卷期：2011年286-37]
- Mammalian target of rapamycin (mTOR) is a kinase that plays a key role in a wide array of cellular processes and exists in two distinct functional complexes, mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2). Although ...
- The F-BAR Protein Rapostlin Regulates Dendritic Spine Formation in Hippocampal Neurons
[作者：Wakita, Y; Kakimoto, T; Katoh, H; Negishi, M,期刊：Journal of Biological Chemistry, 页码：32672-32683 , 文章类型： Article，,卷期：2011年286-37]
- Pombe Cdc15 homology proteins, characterized by Fer/CIP4 homology Bin-Amphiphysin-Rvs/extended Fer/CIP4 homology (F-BAR/EFC) domains with membrane invaginating property, play critical roles in a variety of membrane reorg...
- Lectin Domains of Polypeptide GalNAc Transferases Exhibit Glycopeptide Binding Specificity
[作者：Pedersen, JW; Bennett, EP; Schjoldager, KTBG; Meldal, M; Holmer, AP; Blixt, O; Clo, E; Levery, SB; Clausen, H; Wandall, HH,期刊：Journal of Biological Chemistry, 页码：32684-32696 , 文章类型： Article，,卷期：2011年286-37]
- UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferases (GalNAc-Ts) constitute a family of up to 20 transferases that initiate mucin-type O-glycosylation. The transferases are structurally composed of catalytic ...
- Preclinical Derivation and Imaging of Autologously Transplanted Canine Induced Pluripotent Stem Cells
[作者：Lee, AS; Xu, D; Plews, JR; Nguyen, PK; Nag, D; Lyons, JK; Han, L; Hu, SJ; Lan, F; Liu, JW; Huang, M; Narsinh, KH; Long, CT; de Almeida, PE; Levi, B; Kooreman, N; Bangs, C; Pacharinsak, C; Ikeno, F; Yeung, AC; Gambhir, SS; Robbins, RC; Longaker, MT; Wu, JC,期刊：Journal of Biological Chemistry, 页码：32697-32704 , 文章类型： Article，,卷期：2011年286-37]
- Derivation of patient-specific induced pluripotent stem cells (iPSCs) opens a new avenue for future applications of regenerative medicine. However, before iPSCs can be used in a clinical setting, it is critical to valida...
- CX3CR1 Protein Signaling Modulates Microglial Activation and Protects against Plaque-independent Cognitive Deficits in a Mouse Model of Alzheimer Disease
[作者：Cho, SH; Sun, BG; Zhou, YG; Kauppinen, TM; Halabisky, B; Wes, P; Ransohoff, RM; Gan, L,期刊：Journal of Biological Chemistry, 页码：32713-32722 , 文章类型： Article，,卷期：2011年286-37]
- Aberrant microglial activation has been proposed to contribute to the cognitive decline in Alzheimer disease (AD), but the underlying molecular mechanisms remain enigmatic. Fractalkine signaling, a pathway mediating the ...
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