- Functional Dissection of Adenylate Cyclase R, an Inducer of Spore Encapsulation
[作者:Chen, ZH; Schilde, C; Schaap, P,期刊:Journal of Biological Chemistry, 页码:41724-41731 , 文章类型: Article,,卷期:2010年285-53]
- Cyclic AMP acting on protein kinase A controls sporulation and encystation in social and solitary amoebas. In Dictyostelium discoideum, adenylate cyclase R (ACR), is essential for spore encapsulation. In addition to its ...
- PKC delta Is Activated in a Dietary Model of Steatohepatitis and Regulates Endoplasmic Reticulum Stress and Cell Death
[作者:Greene, MW; Burrington, CM; Ruhoff, MS; Johnson, AK; Chongkrairatanakul, T; Kangwanpornsiri, A,期刊:Journal of Biological Chemistry, 页码:42115-42129 , 文章类型: Article,,卷期:2010年285-53]
- Hepatic steatosis can progress to the clinical condition of non-alcoholic steatohepatitis (NASH), which is a precursor of more serious liver diseases. The novel PKC isoforms delta and epsilon are activated by lipid metab...
- Neogenin-RGMa signaling at the growth cone is bone morphogenetic protein-independent and involves RhoA, ROCK, and PKC (vol 282, pg 16423, 2007)
[作者:Conrad, S; Genth, H; Hofmann, F; Just, I; Skutella, T,期刊:Journal of Biological Chemistry, 页码:42140-42140 , 文章类型: Correction,,卷期:2010年285-53]
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- Fission Yeast Receptor of Activated C Kinase (RACK1) Ortholog Cpc2 Regulates Mitotic Commitment through Wee1 Kinase
[作者:Nunez, A; Franco, A; Soto, T; Vicente, J; Gacto, M; Cansado, J,期刊:Journal of Biological Chemistry, 页码:41366-41373 , 文章类型: Article,,卷期:2010年285-53]
- In the fission yeast Schizosaccharomyces pombe, Wee1-dependent inhibitory phosphorylation of the highly conserved Cdc2/Cdk1 kinase determines the mitotic onset when cells have reached a defined size. The receptor of acti...
- Brain-specific Phgdh Deletion Reveals a Pivotal Role for L-Serine Biosynthesis in Controlling the Level of D-Serine, an N-methyl-D-aspartate Receptor Co-agonist, in Adult Brain
[作者:Yang, JH; Wada, A; Yoshida, K; Miyoshi, Y; Sayano, T; Esaki, K; Kinoshita, MO; Tomonaga, S; Azuma, N; Watanabe, M; Hamase, K; Zaitsu, K; Machida, T; Messing, A; Itohara, S; Hirabayashi, Y; Furuya, S,期刊:Journal of Biological Chemistry, 页码:41380-41390 , 文章类型: Article,,卷期:2010年285-53]
- In mammalian brain, D-serine is synthesized from L-serine by serine racemase, and it functions as an obligatory co-agonist at the glycine modulatory site of N-methyl-D-aspartate (NMDA)-selective glutamate receptors. Alth...
- Cholesterol and Lipid Phases Influence the Interactions between Serotonin Receptor Agonists and Lipid Bilayers
[作者:Batchelor, R; Windle, CJ; Buchoux, S; Lorch, M,期刊:Journal of Biological Chemistry, 页码:41402-41411 , 文章类型: Article,,卷期:2010年285-53]
- Solid state NMR techniques have been used to investigate the effect that two serotonin receptor 1a agonists (quipazine and LY-165,163) have on the phase behavior of, and interactions within, cholesterol/phosphocholine li...
- Dendritic Cell Activation Prevents MHC Class II Ubiquitination and Promotes MHC Class II Survival Regardless of the Activation Stimulus
[作者:Walseng, E; Furuta, K; Goldszmid, RS; Weih, KA; Sher, A; Roche, PA,期刊:Journal of Biological Chemistry, 页码:41749-41754 , 文章类型: Article,,卷期:2010年285-53]
- The expression of MHC class II (MHC-II) on the surface of antigen-presenting cells, such as dendritic cells (DCs), is tightly regulated during cellular activation. Many cells, including DCs, are activated following stimu...
- Homotypic Cell to Cell Cross-talk Among Human Natural Killer Cells Reveals Differential and Overlapping Roles of 2B4 and CD2
[作者:Kim, EO; Kim, TJ; Kim, N; Kim, ST; Kumar, V; Lee, KM,期刊:Journal of Biological Chemistry, 页码:41755-41764 , 文章类型: Article,,卷期:2010年285-53]
- Human natural killer (NK) cells express an abundant level of 2B4 and CD2 on their surface. Their counter-receptors, CD48 and CD58, are also expressed on the NK cell surface, raising a question about the functional conseq...
- Insights into Radicicol Biosynthesis via Heterologous Synthesis of Intermediates and Analogs
[作者:Zhou, H; Qiao, KJ; Gao, ZZ; Vederas, JC; Tang, Y,期刊:Journal of Biological Chemistry, 页码:41412-41421 , 文章类型: Article,,卷期:2010年285-53]
- Resorcylic acid lactones are fungal polyketides that display diverse biological activities, with the potent Hsp90 inhibitor radicicol being an important representative member. Two fungal iterative polyketide synthases (I...
- Imaging of Mobile Long-lived Nanoplatforms in the Live Cell Plasma Membrane
[作者:Brameshuber, M; Weghuber, J; Ruprecht, V; Gombos, I; Horvath, I; Vigh, L; Eckerstorfer, P; Kiss, E; Stockinger, H; Schutz, GJ,期刊:Journal of Biological Chemistry, 页码:41765-41771 , 文章类型: Article,,卷期:2010年285-53]
- The plasma membrane has been hypothesized to contain nanoscopic lipid platforms, which are discussed in the context of "lipid rafts" or "membrane rafts." Based on biochemical and cell biological studies, rafts are believ...
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