- White matter maturation reshapes structural connectivity in the late developing human brain
[作者:Hagmann, P; Sporns, O; Madan, N; Cammoun, L; Pienaar, R; Wedeen, VJ; Meuli, R; Thiran, JP; Grant, PE,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19067-19072 , 文章类型: Article,,卷期:2010年107-44]
- From toddler to late teenager, the macroscopic pattern of axonal projections in the human brain remains largely unchanged while undergoing dramatic functional modifications that lead to network refinement. These function...
- Hierarchical order of coexisting pre- and postsynaptic forms of long-term potentiation at synapses in amygdala
[作者:Shin, RM; Tully, K; Li, Y; Cho, JH; Higuchi, M; Suhara, T; Bolshakov, VY,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19073-19078 , 文章类型: Article,,卷期:2010年107-44]
- Synaptic rules that may determine the interaction between coexisting forms of long-term potentiation (LTP) at glutamatergic central synapses remain unknown. Here, we show that two mechanistically distinct forms of LTP co...
- Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy
[作者:Adamo, CM; Dai, DF; Percival, JM; Minami, E; Willis, MS; Patrucco, E; Froehner, SC; Beavo, JA,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19079-19083 , 文章类型: Article,,卷期:2010年107-44]
- Duchenne muscular dystrophy (DMD) is a progressive and fatal genetic disorder of muscle degeneration. Patients with DMD lack expression of the protein dystrophin as a result of mutations in the X-linked dystrophin gene. ...
- Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis
[作者:Everaerts, W; Zhen, XG; Ghosh, D; Vriens, J; Gevaert, T; Gilbert, JP; Hayward, NJ; McNamara, CR; Xue, FQ; Moran, MM; Strassmaier, T; Uykal, E; Owsianik, G; Vennekens, R; De Ridder, D; Nilius, B; Fanger, CM; Voets, T,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19084-19089 , 文章类型: Article,,卷期:2010年107-44]
- Reduced functional bladder capacity and concomitant increased micturition frequency (pollakisuria) are common lower urinary tract symptoms associated with conditions such as cystitis, prostatic hyperplasia, neurological ...
- CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function
[作者:Andrews, JL; Zhang, X; McCarthy, JJ; McDearmon, EL; Hornberger, TA; Russell, B; Campbell, KS; Arbogast, S; Reid, MB; Walker, JR; Hogenesch, JB; Takahashi, JS; Esser, KA,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19090-19095 , 文章类型: Article,,卷期:2010年107-44]
- MyoD, a master regulator of myogenesis, exhibits a circadian rhythm in its mRNA and protein levels, suggesting a possible role in the daily maintenance of muscle phenotype and function. We report that MyoD is a direct ta...
- Thromboxane A2 receptor and MaxiK-channel intimate interaction supports channel trans-inhibition independent of G-protein activation
[作者:Li, M; Tanaka, Y; Alioua, A; Wu, Y; Lu, R; Kundu, P; Sanchez-Pastor, E; Marijic, J; Stefani, E; Toro, L,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19096-19101 , 文章类型: Article,,卷期:2010年107-44]
- Large conductance voltage- and calcium-activated potassium channels (MaxiK, BKCa) are well known for sustaining cerebral and coronary arterial tone and for their linkage to vasodilator beta-adrenergic receptors. However,...
- Crystal and solution structures of an odorant-binding protein from the southern house mosquito complexed with an oviposition pheromone
[作者:Mao, Y; Xu, XZ; Xu, W; Ishida, Y; Leal, WS; Ames, JB; Clardy, J,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19102-19107 , 文章类型: Article,,卷期:2010年107-44]
- Culex mosquitoes introduce the pathogens responsible for filariasis, West Nile virus, St. Louis encephalitis, and other diseases into humans. Currently, traps baited with oviposition semiochemicals play an important role...
- A seed coat bedding assay shows that RGL2-dependent release of abscisic acid by the endosperm controls embryo growth in Arabidopsis dormant seeds
[作者:Lee, KP; Piskurewicz, U; Tureckova, V; Strnad, M; Lopez-Molina, L,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19108-19113 , 文章类型: Article,,卷期:2010年107-44]
- Seed dormancy is an ecologically important adaptive trait in plants whereby germination is repressed even under favorable germination conditions such as imbibition with water. In Arabidopsis and most plant species, dorma...
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