- Greenhouse gas emissions from alternative futures of deforestation and agricultural management in the southern Amazon
[作者:Galford, GL; Melillo, JM; Kicklighter, DW; Cronin, TW; Cerri, CEP; Mustard, JF; Cerri, CC,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19649-19654 , 文章类型: Article,,卷期:2010年107-46]
- The Brazilian Amazon is one of the most rapidly developing agricultural areas in the world and represents a potentially large future source of greenhouse gases from land clearing and subsequent agricultural management. I...
- Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate
[作者:Arwert, EN; Lal, R; Quist, S; Rosewell, I; van Rooijen, N; Watt, FM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19903-19908 , 文章类型: Article,,卷期:2010年107-46]
- Inmammalian epidermis, integrin expression is normally confined to the basal proliferative layer that contains stem cells. However, in epidermal hyperproliferative disorders and tumors, integrins are also expressed by su...
- Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains
[作者:Miao, BC; Skidan, I; Yang, JS; Lugovskoy, A; Reibarkh, M; Long, K; Brazell, T; Durugkar, KA; Maki, J; Ramana, CV; Schaffhausen, B; Wagner, G; Torchilin, V; Yuan, JY; Degterev, A,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20126-20131 , 文章类型: Article,,卷期:2010年107-46]
- The PI3-kinase (PI3K) pathway regulates many cellular processes, especially cell metabolism, cell survival, and apoptosis. Phosphatidylinositol-3,4,5-trisphosphate (PIP3), the product of PI3K activity and a key signaling...
- Negative feedback regulation of UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis
[作者:Gruber, H; Heijde, M; Heller, W; Albert, A; Seidlitz, HK; Ulm, R,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20132-20137 , 文章类型: Article,,卷期:2010年107-46]
- Plants respond to low levels of UV-B radiation with a coordinated photomorphogenic response that allows acclimation to this environmental stress factor. The key players in this UV-B response are COP1 (an E3 ubiquitin lig...
- Identifying potential synergies and trade-offs for meeting food security and climate change objectives in sub-Saharan Africa
[作者:Palm, CA; Smukler, SM; Sullivan, CC; Mutuo, PK; Nyadzi, GI; Walsh, MG,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19661-19666 , 文章类型: Article,,卷期:2010年107-46]
- Potential interactions between food production and climate mitigation are explored for two situations in sub-Saharan Africa, where deforestation and land degradation overlap with hunger and poverty. Three agriculture int...
- Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells
[作者:Sun, Y; Bilan, PJ; Liu, Z; Klip, A,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19909-19914 , 文章类型: Article,,卷期:2010年107-46]
- Skeletal muscle is the primary site of dietary glucose disposal, a function that depends on insulin-mediated exocytosis of GLUT4 vesicles to its cell surface. In skeletal muscle and adipocytes, this response involves Akt...
- Exposing malaria in-host diversity and estimating population diversity by capture-recapture using massively parallel pyrosequencing
[作者:Juliano, JJ; Porter, K; Mwapasa, V; Sem, R; Rogers, WO; Ariey, F; Wongsrichanalai, C; Read, A; Meshnick, SR,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20138-20143 , 文章类型: Article,,卷期:2010年107-46]
- Malaria infections commonly contain multiple genetically distinct variants. Mathematical and animal models suggest that interactions among these variants have a profound impact on the emergence of drug resistance. Howeve...
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