- X-ray Structure and Mutational Analysis of the Atrazine Chlorohydrolase TrzN
[作者:Seffernick, JL; Reynolds, E; Fedorov, AA; Fedorov, E; Almo, SC; Sadowsky, MJ; Wackett, LP,期刊:Journal of Biological Chemistry, 页码:30606-30614 , 文章类型: Article,,卷期:2010年285-40]
- Atrazine chlorohydrolase, TrzN (triazine hydrolase or atrazine chlorohydrolase 2), initiates bacterial metabolism of the herbicide atrazine by hydrolytic displacement of a chlorine substituent from the s-triazine ring. T...
- Deciphering the Hidden Informational Content of Protein Sequences FOLDABILITY OF PROINSULIN HINGES ON A FLEXIBLE ARM THAT IS DISPENSABLE IN THE MATURE HORMONE
[作者:Liu, M; Hua, QX; Hu, SQ; Jia, WH; Yang, YW; Saith, SE; Whittaker, J; Arvan, P; Weiss, MA,期刊:Journal of Biological Chemistry, 页码:30989-31001 , 文章类型: Article,,卷期:2010年285-40]
- Protein sequences encode both structure and foldability. Whereas the interrelationship of sequence and structure has been extensively investigated, the origins of folding efficiency are enigmatic. We demonstrate that the...
- Somatic Nucleus Reprogramming Is Significantly Improved by m-Carboxycinnamic Acid Bishydroxamide, a Histone Deacetylase Inhibitor
[作者:Dai, XP; Hao, J; Hou, XJ; Hai, T; Fan, Y; Yu, Y; Jouneau, A; Wang, L; Zhou, Q,期刊:Journal of Biological Chemistry, 页码:31002-31010 , 文章类型: Article,,卷期:2010年285-40]
- Somatic cell nuclear transfer (SCNT) has shown tremendous potential for understanding the mechanisms of reprogramming and creating applications in the realms of agriculture, therapeutics, and regenerative medicine, altho...
- kappa B-Ras Is a Nuclear-Cytoplasmic Small GTPase That Inhibits NF-kappa B Activation through the Suppression of Transcriptional Activation of p65/RelA
[作者:Tago, K; Funakoshi-Tago, M; Sakinawa, M; Mizuno, N; Itoh, H,期刊:Journal of Biological Chemistry, 页码:30622-30633 , 文章类型: Article,,卷期:2010年285-40]
- NF-kappa B is an important transcription factor involved in various biological responses, including inflammation, cell differentiation, and tumorigenesis. kappa B-Ras was identified as an I kappa B-interacting small GTPa...
- Plasma Membrane Ca2+-ATPase Overexpression Depletes Both Mitochondrial and Endoplasmic Reticulum Ca2+ Stores and Triggers Apoptosis in Insulin-secreting BRIN-BD11 Cells
[作者:Jiang, L; Allagnat, F; Nguidjoe, E; Kamagate, A; Pachera, N; Vanderwinden, JM; Brini, M; Carafoli, E; Eizirik, DL; Cardozo, AK; Herchuelz, A,期刊:Journal of Biological Chemistry, 页码:30634-30643 , 文章类型: Article,,卷期:2010年285-40]
- Ca2+ may trigger apoptosis in beta-cells. Hence, the control of intracellular Ca2+ may represent a potential approach to prevent beta-cell apoptosis in diabetes. Our objective was to investigate the effect and mechanism ...
- Peroxisomal and Microsomal Lipid Pathways Associated with Resistance to Hepatic Steatosis and Reduced Pro-inflammatory State
[作者:Hall, D; Poussin, C; Velagapudi, VR; Empsen, C; Joffraud, M; Beckmann, JS; Geerts, AE; Ravussin, Y; Ibberson, M; Oresic, M; Thorens, B,期刊:Journal of Biological Chemistry, 页码:31011-31023 , 文章类型: Article,,卷期:2010年285-40]
- Accumulation of fat in the liver increases the risk to develop fibrosis and cirrhosis and is associated with development of the metabolic syndrome. Here, to identify genes or gene pathways that may underlie the genetic s...
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