- Synthesis, anticonvulsant and CNS depressant activity of some new bioactive 1-(4-substituted-phenyl)-3-(4-oxo-2-phenyl/ethyl-4H-quinazolin-3-yl)-urea
[作者:Kashaw, SK; Kashaw, V; Mishra, P; Jain, NK; Stables, JP,期刊:European Journal of Medicinal Chemistry, 页码:4335-4343 , 文章类型: Article,,卷期:2009年44-11]
- Several new 1-(4-substituted-phenyl)-3-(4-oxo-2-phenyi/ethyl-4H-quinazolin-3-yl)-urea were synthesized and screened for anticonvulsant, CNS depressant and sedative-hypnotic activity in the mice. After i.p. injection to m...
- 3D-QSAR CoMFA/CoMSIA models based on theoretical active conformers of HOE/BAY-793 analogs derived from HIV-1 protease inhibitor complexes
[作者:da Cunha, EFF; Sippl, W; Ramalho, TC; Antunes, OAC; de Alencastro, RB; Albuquerque, MG,期刊:European Journal of Medicinal Chemistry, 页码:4344-4352 , 文章类型: Article,,卷期:2009年44-11]
- The three-dimensional quantitative structure-activity relationships (3D-QSAR) of a series of HOE/BAY-793 analogs (C-2-symmetric diol peptidomimetics), developed by Budt and co-workers [Bioorg. Med. Chem. 3 (1995) 559] as...
- Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds
[作者:Aghatabay, NM; Bas, A; Kircali, A; Sen, G; Yazicioglu, MB; Gucin, F; Dulger, B,期刊:European Journal of Medicinal Chemistry, 页码:4681-4689 , 文章类型: Article,,卷期:2009年44-11]
- Series of new mixed aza-oxo-thia macrocyclic ligands 1,9(2,6)-ditriazina-2,8,10,16-tetraaza-3,7,11,15-tetraoxo-5,13-dithia-cyclohexadecaphan-1(4),9(4)-diphenyl (L-1); 1,10(2,6)-ditriazina-2,9,11,18-tetraaza-3,8,12, 17-te...
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