- Organization of Cytochrome P450 Enzymes Involved in Sex Steroid Synthesis PROTEIN-PROTEIN INTERACTIONS IN LIPID MEMBRANES
[作者:Praporski, S; Ng, SM; Nguyen, AD; Corbin, CJ; Mechler, A; Zheng, J; Conley, AJ; Martin, LL,期刊:Journal of Biological Chemistry, 页码:33224-33232 , 文章类型: Article,,卷期:2009年284-48]
- Mounting evidence underscores the importance of protein-protein interactions in the functional regulation of drug-metabolizing P450s, but few studies have been conducted in membrane environments, and none have examined P...
- Cyclin D1 Induction by Benzo[a]pyrene-7,8-diol-9,10-epoxide via the Phosphatidylinositol 3-Kinase/Akt/MAPK- and p70(s6k)-dependent Pathway Promotes Cell Transformation and Tumorigenesis
[作者:Ding, J; Ning, BF; Gong, WF; Wen, W; Wu, K; Liang, JQ; He, GP; Huang, SN; Sun, W; Han, T; Huang, L; Cao, GW; Wu, MC; Xie, WF; Wang, HY,期刊:Journal of Biological Chemistry, 页码:33311-33319 , 文章类型: Article,,卷期:2009年284-48]
- Benzo[a]pyrene-7,8-diol-9,10-epoxide (B[a]PDE), the major metabolite of B[a] P, has been well recognized as one ubiquitous carcinogen, but the molecular mechanism involved in its carcinogenic effect remains obscure. In t...
- Depletion of Vitamin E Increases Amyloid beta Accumulation by Decreasing Its Clearances from Brain and Blood in a Mouse Model of Alzheimer Disease
[作者:Nishida, Y; Ito, S; Ohtsuki, S; Yamamoto, N; Takahashi, T; Iwata, N; Jishage, K; Yamada, H; Sasaguri, H; Yokota, S; Piao, WY; Tomimitsu, H; Saido, TC; Yanagisawa, K; Terasaki, T; Mizusawa, H; Yokota, T,期刊:Journal of Biological Chemistry, 页码:33400-33408 , 文章类型: Article,,卷期:2009年284-48]
- Increased oxidative damage is a prominent and early feature in Alzheimer disease. We previously crossed Alzheimer disease transgenic (APPsw) model mice with alpha-tocopherol transfer protein knock-out (Ttpa(-/-)) mice in...
- Effect of Anaplerotic Fluxes and Amino Acid Availability on Hepatic Lipoapoptosis
[作者:Noguchi, Y; Young, JD; Aleman, JO; Hansen, ME; Kelleher, JK; Stephanopoulos, G,期刊:Journal of Biological Chemistry, 页码:33425-33436 , 文章类型: Article,,卷期:2009年284-48]
- To identify metabolic pathways involved in hepatic lipoapoptosis, metabolic flux analysis using [U-C-13(5)]glutamine as an isotopic tracer was applied to quantify phenotypic changes in H4IIEC3 hepatoma cells treated with...
- Two Novel Functions of Hyaluronidase-2 (Hyal2) Are Formation of the Glycocalyx and Control of CD44-ERM Interactions
[作者:Duterme, C; Mertens-Strijthagen, J; Tammi, M; Flamion, B,期刊:Journal of Biological Chemistry, 页码:33495-33508 , 文章类型: Article,,卷期:2009年284-48]
- It has long been predicted that the members of the hyaluronidase enzyme family have important non-enzymatic functions. However, their nature remains a mystery. The metabolism of hyaluronan (HA), their major enzymatic sub...
|