- Crystal structure and catalytic mechanism of PglD from Campylobacter jejuni
[作者:Olivier, NB; Imperiali, B,期刊:Journal of Biological Chemistry, 页码:27937-27946 , 文章类型: Article,,卷期:2008年283-41]
- The carbohydrate 2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose (BacAc(2)) is found in a variety of eubacterial pathogens. In Campylobacter jejuni, PglD acetylates the C4 amino group on UDP-2-acetamido-4-amino-2,4,...
- Nuclear co-translocation of myotrophin and p65 stimulates myocyte growth - Regulation by myotrophin hairpin loops
[作者:Das, B; Gupta, S; Vasanji, A; Xu, Z; Misra, S; Sen, S,期刊:Journal of Biological Chemistry, 页码:27947-27956 , 文章类型: Article,,卷期:2008年283-41]
- Myotrophin, a 12-kDa ankyrin repeat protein, stimulates protein synthesis and cardiomyocyte growth to initiate cardiac hypertrophy by activating the NF-kappa B signaling cascade. We found that, after internalization into...
- Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells
[作者:Bhatia, B; Jiang, M; Suraneni, M; Patrawala, L; Badeaux, M; Schneider-Broussard, R; Multani, AS; Jeter, CR; Calhoun-Davis, T; Hu, LM; Hu, JH; Tsavachidis, S; Zhang, W; Chang, S; Hayward, SW; Tang, DG,期刊:Journal of Biological Chemistry, 页码:27957-27972 , 文章类型: Article,,卷期:2008年283-41]
- Normal human prostate (NHP) epithelial cells undergo senescence in vitro and in vivo, but the underlying molecular mechanisms remain obscure. Here we show that the senescence of primary NHP cells, which are immunophenoty...
- Disulfide cross-links reveal conserved features of DNA topoisomerase I architecture and a role for the n terminus in clamp closure
[作者:Palle, K; Pattarello, L; van der Merwe, M; Losasso, C; Benedetti, P; Bjornsti, MA,期刊:Journal of Biological Chemistry, 页码:27767-27775 , 文章类型: Article,,卷期:2008年283-41]
- In eukaryotes, DNA topoisomerase I (Top1) catalyzes the relaxation of supercoiled DNA by a conserved mechanism of transient DNA strand breakage, rotation, and religation. The unusual architecture of the monomeric human e...
- Monothiol glutaredoxin-1 is an essential iron-sulfur protein in the mitochondrion of African trypanosomes
[作者:Comini, MA; Rettig, J; Dirdjaja, N; Hanschmann, EM; Berndt, C; Krauth-Siegel, RL,期刊:Journal of Biological Chemistry, 页码:27785-27798 , 文章类型: Article,,卷期:2008年283-41]
- African trypanosomes encode three monothiol glutaredoxins (1-C-Grx). 1-C-Grx1 occurs exclusively in the mitochondrion, and 1-C-Grx2 and -3 are predicted to be mitochondrial and cytosolic proteins, respectively. All three...
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