- Human alpha-Defensins Inhibit BK Virus Infection by Aggregating Virions and Blocking Binding to Host Cells
[作者:Dugan, AS; Maginnis, MS; Jordan, JA; Gasparovic, ML; Manley, K; Page, R; Williams, G; Porter, E; O'Hara, BA; Atwood, WJ,期刊:Journal of Biological Chemistry, 页码:31125-31132 , 文章类型: Article,,卷期:2008年283-45]
- BK virus (BKV) is a polyomavirus that establishes a lifelong persistence in most humans and is a major impediment to success of kidney grafts. The function of the innate immune system in BKV infection and pathology has n...
- An Unusual Intrinsically Disordered Protein from the Model Legume Lotus japonicus Stabilizes Proteins in Vitro
[作者:Haaning, S; Radutoiu, S; Hoffmann, SV; Dittmer, J; Giehm, L; Otzen, DE; Stougaard, J,期刊:Journal of Biological Chemistry, 页码:31142-31152 , 文章类型: Article,,卷期:2008年283-45]
- Intrinsic structural disorder is a prevalent feature of proteins with chaperone activity. Using a complementary set of techniques, we have structurally characterized LjIDP1 (intrinsically disordered protein 1) from the m...
- c-Fos Activates Glucosylceramide Synthase and Glycolipid Synthesis in PC12 Cells
[作者:Crespo, PM; Silvestre, DC; Gil, GA; Maccioni, HJF; Daniotti, JL; Caputto, BL,期刊:Journal of Biological Chemistry, 页码:31163-31171 , 文章类型: Article,,卷期:2008年283-45]
- It has been demonstrated that c-Fos has, in addition to its well recognized AP-1 transcription factor activity, the capacity to associate to the endoplasmic reticulum and activate key enzymes involved in the synthesis of...
- Glucocorticoid Receptor-mediated Expression of Caldesmon Regulates Cell Migration via the Reorganization of the Actin Cytoskeleton
[作者:Mayanagi, T; Morita, T; Hayashi, K; Fukumoto, K; Sobue, K,期刊:Journal of Biological Chemistry, 页码:31183-31196 , 文章类型: Article,,卷期:2008年283-45]
- Glucocorticoids (GCs) play important roles in numerous cellular processes, including growth, development, homeostasis, inhibition of inflammation, and immunosuppression. Here we found that GC-treated human lung carcinoma...
- Flavonoids Redirect PIN-mediated Polar Auxin Fluxes during Root Gravitropic Responses
[作者:Santelia, D; Henrichs, S; Vincenzetti, V; Sauer, M; Bigler, L; Klein, M; Bailly, A; Lee, Y; Friml, J; Geisler, M; Martinoia, E,期刊:Journal of Biological Chemistry, 页码:31218-31226 , 文章类型: Article,,卷期:2008年283-45]
- The rate, polarity, and symmetry of the flow of the plant hormone auxin are determined by the polar cellular localization of PIN-FORMED (PIN) auxin efflux carriers. Flavonoids, a class of secondary plant metabolites, hav...
- A Phospholipid Substrate Molecule Residing in the Membrane Surface Mediates Opening of the Lid Region in Group IVA Cytosolic Phospholipase A(2)
[作者:Burke, JE; Hsu, YH; Deems, RA; Li, S; Woods, VL; Dennis, EA,期刊:Journal of Biological Chemistry, 页码:31227-31236 , 文章类型: Article,,卷期:2008年283-45]
- The Group IVA (GIVA) phospholipase A(2) associates with natural membranes in response to an increase in intracellular Ca2+ along with increases in certain lipid mediators. This enzyme associates with the membrane surface...
- Identification of Aurora-A as a Direct Target of E2F3 during G(2)/M Cell Cycle Progression
[作者:He, LL; Yang, H; Ma, YH; Pledger, WJ; Cress, WD; Cheng, JQ,期刊:Journal of Biological Chemistry, 页码:31012-31020 , 文章类型: Article,,卷期:2008年283-45]
- Aurora-A is a centrosome kinase and plays a pivotal role in G(2)/M cell cycle progression. Expression of Aurora-A is cell cycle-dependent. Levels of Aurora-A mRNA and protein are low in G(1)/S, accumulate during G(2)/M, ...
- Regulation of Cyst Wall Protein Promoters by Myb2 in Giardia lamblia
[作者:Huang, YC; Su, LH; Lee, GA; Chiu, PW; Cho, CC; Wu, JY; Sun, CH,期刊:Journal of Biological Chemistry, 页码:31021-31029 , 文章类型: Article,,卷期:2008年283-45]
- Myb family transcription factors are important in regulating cell proliferation, differentiation, and cell cycle progression. Giardia lamblia differentiates into infectious cysts to survive outside of the host. During en...
- Cyclic AMP-induced Chromatin Changes Support the NFATc-mediated Recruitment of GATA-3 to the Interleukin 5 Promoter
[作者:Klein-Hessling, S; Bopp, T; Jha, MK; Schmidt, A; Miyatake, S; Schmitt, E; Serfling, E,期刊:Journal of Biological Chemistry, 页码:31030-31037 , 文章类型: Article,,卷期:2008年283-45]
- Elevated intracellular cyclic AMP levels, which suppress the proliferation of naive T cells and type 1 T helper (Th1) cells are a property of T helper 2 (Th2) cells and regulatory T cells. While cyclic AMP signals interf...
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