- Human T-cell Leukemia Virus Type 1 HBZ Protein Bypasses the Targeting Function of Ubiquitination
[作者:Isono, O; Ohshima, T; Saeki, Y; Matsumoto, J; Hijikata, M; Tanaka, K; Shimotohno, K,期刊:Journal of Biological Chemistry, 页码:34273-34282 , 文章类型: Article,,卷期:2008年283-49]
- Human T-cell leukemia virus type 1 (HTLV-1) encodes an antisense viral gene product termed HTLV-1 basic leucine-zipper factor (HBZ). HBZ forms heterodimers with c-Jun, a member of the AP-1 family, and promotes its protea...
- p66(Shc)-generated Oxidative Signal Promotes Fat Accumulation
[作者:Berniakovich, I; Trinei, M; Stendardo, M; Migliaccio, E; Minucci, S; Bernardi, P; Pelicci, PG; Giorgio, M,期刊:Journal of Biological Chemistry, 页码:34283-34293 , 文章类型: Article,,卷期:2008年283-49]
- Reactive oxygen species (ROS) and insulin signaling in the adipose tissue are critical determinants of aging and age-associated diseases. It is not clear, however, if they represent independent factors or they are mechan...
- Involvement of Highly Sulfated Chondroitin Sulfate in the Metastasis of the Lewis Lung Carcinoma Cells
[作者:Li, F; ten Dam, GB; Murugan, S; Yamada, S; Hashiguchi, T; Mizumoto, S; Oguri, K; Okayama, M; van Kuppevelt, TH; Sugahara, K,期刊:Journal of Biological Chemistry, 页码:34294-34304 , 文章类型: Article,,卷期:2008年283-49]
- The altered expression of cell surface chondroitin sulfate ( CS) and dermatan sulfate (DS) in cancer cells has been demonstrated to play a key role in malignant transformation and tumor metastasis. However, the functiona...
- Transcriptional Repression of the Prosurvival Endoplasmic Reticulum Chaperone GRP78/BIP by E2F1
[作者:Racek, T; Buhlmann, S; Rust, F; Knoll, S; Alla, V; Putzer, BM,期刊:Journal of Biological Chemistry, 页码:34305-34314 , 文章类型: Article,,卷期:2008年283-49]
- The endoplasmic reticulum chaperone GRP78/BIP plays a central role in the prosurvival machinery, and its enhanced expression has been implicated in drug resistance, carcinogenesis, and metastasis. E2F1, as part of an ant...
- ClC-3 and IClswell are Required for Normal Neutrophil Chemotaxis and Shape Change
[作者:Volk, APD; Heise, CK; Hougen, JL; Artman, CM; Volk, KA; Wessels, D; Soll, DR; Nauseef, WM; Lamb, FS; Moreland, JG,期刊:Journal of Biological Chemistry, 页码:34315-34326 , 文章类型: Article,,卷期:2008年283-49]
- Polymorphonuclear leukocytes undergo directed movement to sites of infection, a complex process known as chemotaxis. Extension of the polymorphonuclear leukocyte (PMN) leading edge toward a chemoattractant in association...
- Selective Regulation of Heme Oxygenase-1 Expression and Function by Insulin through IRS1/Phosphoinositide 3-Kinase/Akt-2 Pathway
[作者:Geraldes, P; Yagi, K; Ohshiro, Y; He, ZH; Maeno, Y; Yamamoto-Hiraoka, J; Rask-Madsen, C; Chung, SW; Perrella, MA; King, GL,期刊:Journal of Biological Chemistry, 页码:34327-34336 , 文章类型: Article,,卷期:2008年283-49]
- Heme oxygenase 1 (HO-1) is a representative mediator of antioxidants and cytoprotectants against various stress stimuli including oxidants in vascular cells. Intensive insulin treatment can delay the onset and progressio...
- Recombinant Collagen Studies Link the Severe Conformational Changes Induced by Osteogenesis Imperfecta Mutations to the Disruption of a Set of Interchain Salt Bridges
[作者:Xu, K; Nowak, I; Kirchner, M; Xu, YJ,期刊:Journal of Biological Chemistry, 页码:34337-34344 , 文章类型: Article,,卷期:2008年283-49]
- The clinical severity of Osteogenesis Imperfecta (OI), also known as the brittle bone disease, relates to the extent of conformational changes in the collagen triple helix induced by Gly substitution mutations. The linge...
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