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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共59条记录   Primary epimutations introduced during intracytoplasmic sperm injection (ICSI) are corrected by germline-specific epigenetic reprogramming [作者：de Waal, E; Yamazaki, Y; Ingale, P; Bartolomei, M; Yanagimachi, R; McCarrey, JR,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：4163-4168 , 文章类型： Article，,卷期：2012年109-11] The use of assisted reproductive technologies (ART) has become increasingly common worldwide and is now responsible for 2-3% of children born in developed countries. Multiple reports have suggested that ART-conceived chi... Calcium influx-mediated signaling is required for complete mouse egg activation [作者：Miao, YL; Stein, P; Jefferson, WN; Padilla-Banks, E; Williams, CJ,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：4169-4174 , 文章类型： Article，,卷期：2012年109-11] Mammalian fertilization is accompanied by oscillations in egg cytoplasmic calcium (Ca2+) concentrations that are critical for completion of egg activation. These oscillations are initiated by Ca2+ release from inositol 1... A cold oceanographic regime with high exploitation rates in the Northeast Pacific forecasts a collapse of the sardine stock [作者：Zwolinski, JP; Demer, DA,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：4175-4180 , 文章类型： Article，,卷期：2012年109-11] The oceanographic conditions in the north Pacific have shifted to a colder period, Pacific sardine (Sardinops sagax) biomass has declined precipitously in the California Current, the international sardine fishery is coll... Strong relationship between elemental stoichiometry and metabolome in plants [作者：Rivas-Ubach, A; Sardans, J; Perez-Trujillo, M; Estiarte, M; Penuelas, J,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：4181-4186 , 文章类型： Article，,卷期：2012年109-11] Shifts in the elemental stoichiometry of organisms in response to their ontogeny and to changing environmental conditions should be related tometabolomic changes because elements operatemostly as parts of molecular compo... The maximum rate of mammal evolution [作者：Evans, AR; Jones, D; Boyer, AG; Brown, JH; Costa, DP; Ernest, SKM; Fitzgerald, EMG; Fortelius, M; Gittleman, JL; Hamilton, MJ; Harding, LE; Lintulaakso, K; Lyons, SK; Okie, JG; Saarinen, JJ; Sibly, RM; Smith, FA; Stephens, PR; Theodor, JM; Uhen, MD,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：4187-4190 , 文章类型： Article，,卷期：2012年109-11] How fast can a mammal evolve from the size of a mouse to the size of an elephant? Achieving such a large transformation calls for major biological reorganization. Thus, the speed at which this occurs has important implic... Evolution in coyotes (Canis latrans) in response to the megafaunal extinctions [作者：Meachen, JA; Samuels, JX,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：4191-4196 , 文章类型： Article，,卷期：2012年109-11] Living coyotes modify their behavior in the presence of larger carnivores, such as wolves. However, little is known about the effects of competitor presence or absence on morphological change in coyotes or wolves over lo... Adaptive horizontal transfer of a bacterial gene to an invasive insect pest of coffee [作者：Acuna, R; Padilla, BE; Florez-Ramos, CP; Rubio, JD; Herrera, JC; Benavides, P; Lee, SJ; Yeats, TH; Egan, AN; Doyle, JJ; Rose, JKC,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：4197-4202 , 文章类型： Article，,卷期：2012年109-11] Horizontal gene transfer (HGT) involves the nonsexual transmission of genetic material across species boundaries. Although often detected in prokaryotes, examples of HGT involving animals are relatively rare, and any evo... Multiple self-splicing introns in the 16S rRNA genes of giant sulfur bacteria [作者：Salman, V; Amann, R; Shub, DA; Schulz-Vogt, HN,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：4203-4208 , 文章类型： Article，,卷期：2012年109-11] The gene encoding the small subunit rRNA serves as a prominent tool for the phylogenetic analysis and classification of Bacteria and Archaea owing to its high degree of conservation and its fundamental function in living... Telomere maintenance and telomerase activity are differentially regulated in asexual and sexual worms [作者：Tan, TCJ; Rahman, R; Jaber-Hijazi, F; Felix, DA; Chen, C; Louis, EJ; Aboobaker, A,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：4209-4214 , 文章类型： Article，,卷期：2012年109-11] In most sexually reproducing animals, replication and maintenance of telomeres occurs in the germ line and during early development in embryogenesis through the use of telomerase. Somatic cells generally do not maintain ... Identification of innate immunity elicitors using molecular signatures of natural selection [作者：McCann, HC; Nahal, H; Thakur, S; Guttman, DS,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：4215-4220 , 文章类型： Article，,卷期：2012年109-11] The innate immune system is an ancient and broad-spectrum defense system found in all eukaryotes. The detection of microbial elicitors results in the up-regulation of defense-related genes and the elicitation of inflamma... RNase H-mediated degradation of toxic RNA in myotonic dystrophy type 1 [作者：Lee, JE; Bennett, CF; Cooper, TA,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：4221-4226 , 文章类型： Article，,卷期：2012年109-11] Myotonic dystrophy type 1 (DM1) is an RNA-dominant disease caused by abnormal transcripts containing expanded CUG repeats. The CUG transcripts aggregate in the nucleus to form RNA foci and lead to nuclear depletion of Mu...