- Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses
[作者:Pica, N; Hai, R; Krammer, F; Wang, TT; Maamary, J; Eggink, D; Tan, GS; Krause, JC; Moran, T; Stein, CR; Banach, D; Wrammert, J; Belshe, RB; Garcia-Sastre, A; Palese, P,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2573-2578 , 文章类型: Article,,卷期:2012年109-7]
- After the emergence of pandemic influenza viruses in 1957, 1968, and 2009, existing seasonal viruses were observed to be replaced in the human population by the novel pandemic strains. We have previously hypothesized tha...
- Exclusive recognition of sarcosine in water and urine by a cavitand-functionalized silicon surface
[作者:Biavardi, E; Tudisco, C; Maffei, F; Motta, A; Massera, C; Condorelli, GG; Dalcanale, E,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2263-2268 , 文章类型: Article,,卷期:2012年109-7]
- A supramolecular approach for the specific detection of sarcosine, recently linked to the occurrence of aggressive prostate cancer forms, has been developed. A hybrid active surface was prepared by the covalent anchoring...
- Dominant eukaryotic export production during ocean anoxic events reflects the importance of recycled NH4+
[作者:Higgins, MB; Robinson, RS; Husson, JM; Carter, SJ; Pearson, A,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2269-2274 , 文章类型: Article,,卷期:2012年109-7]
- The Mesozoic is marked by several widespread occurrences of intense organic matter burial. Sediments from the largest of these events, the Cenomanian-Turonian Oceanic Anoxic Event (OAE 2) are characterized by lower nitro...
- Avian influenza virus hemagglutinins H2, H4, H8, and H14 support a highly pathogenic phenotype
[作者:Veits, J; Weber, S; Stech, O; Breithaupt, A; Graber, M; Gohrbandt, S; Bogs, J; Hundt, J; Teifke, JP; Mettenleiter, TC; Stech, J,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2579-2584 , 文章类型: Article,,卷期:2012年109-7]
- High-pathogenic avian influenza viruses (HPAIVs) evolve from low-pathogenic precursors specifying the HA serotypes H5 or H7 by acquisition of a polybasic HA cleavage site. As the reason for this serotype restriction has ...
- Reentrant spiral waves of spreading depression cause macular degeneration in hypoglycemic chicken retina
[作者:Yu, YF; Santos, LM; Mattiace, LA; Costa, ML; Ferreira, LC; Benabou, K; Kim, AH; Abrahams, J; Bennett, MVL; Rozental, R,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2585-2589 , 文章类型: Article,,卷期:2012年109-7]
- Spreading depression (SD), a slow diffusion-mediated self-sustained wave of depolarization that severely disrupts neuronal function, has been implicated as a cause of cellular injury in a number of central nervous system...
- Spatial navigation impairment is proportional to right hippocampal volume
[作者:Nedelska, Z; Andel, R; Laczo, J; Vlcek, K; Horinek, D; Lisy, J; Sheardova, K; Bures, J; Hort, J,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2590-2594 , 文章类型: Article,,卷期:2012年109-7]
- Cognitive deficits in older adults attributable to Alzheimer's disease (AD) pathology are featured early on by hippocampal impairment. Among these individuals, deterioration in spatial navigation, manifested by poor hipp...
- Enabling high-temperature nanophotonics for energy applications
[作者:Yeng, YX; Ghebrebrhan, M; Bermel, P; Chan, WR; Joannopoulos, JD; Soljacic, M; Celanovic, I,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2280-2285 , 文章类型: Article,,卷期:2012年109-7]
- The nascent field of high-temperature nanophotonics could potentially enable many important solid-state energy conversion applications, such as thermophotovoltaic energy generation, selective solar absorption, and select...
- Continuous and discontinuous quantum phase transitions in a model two-dimensional magnet
[作者:Haravifard, S; Banerjee, A; Lang, JC; Srajer, G; Silevitch, DM; Gaulin, BD; Dabkowska, HA; Rosenbaum, TF,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2286-2289 , 文章类型: Article,,卷期:2012年109-7]
- The Shasty-Sutherland model, which consists of a set of spin 1/2 dimers on a 2D square lattice, is simple and soluble but captures a central theme of condensed matter physics by sitting precariously on the quantum edge b...
- Regulation of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) by reversible lysine acetylation
[作者:Zhang, CF; Majerus, PW; Wilson, MP,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2290-2295 , 文章类型: Article,,卷期:2012年109-7]
- The enzyme inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) catalyzes the rate-limiting step in the formation of higher phosphorylated forms of inositol in mammalian cells. Because it sits at a key regulatory point in the...
- Chondroitinase ABC promotes selective reactivation of somatosensory cortex in squirrel monkeys after a cervical dorsal column lesion
[作者:Bowes, C; Massey, JM; Burish, M; Cerkevich, CM; Kaas, JH,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2595-2600 , 文章类型: Article,,卷期:2012年109-7]
- After large but incomplete lesions of ascending dorsal column afferents in the cervical spinal cord, the hand representation in the contralateral primary somatosensory cortex (area 3b) of monkeys is largely or completely...
- Intermediate conductance calcium-activated potassium channels modulate summation of parallel fiber input in cerebellar Purkinje cells
[作者:Engbers, JDT; Anderson, D; Asmara, H; Rehak, R; Mehaffey, WH; Hameed, S; McKay, BE; Kruskic, M; Zamponi, GW; Turner, RW,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2601-2606 , 文章类型: Article,,卷期:2012年109-7]
- Encoding sensory input requires the expression of postsynaptic ion channels to transform key features of afferent input to an appropriate pattern of spike output. Although Ca2+-activated K+ channels are known to control ...
- foraging alters resilience/vulnerability to sleep disruption and starvation in Drosophila
[作者:Donlea, J; Leahy, A; Thimgan, MS; Suzuki, Y; Hughson, BN; Sokolowski, MB; Shaw, PJ,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2613-2618 , 文章类型: Article,,卷期:2012年109-7]
- Recent human studies suggest that genetic polymorphisms allow an individual to maintain optimal cognitive functioning during sleep deprivation. If such polymorphisms were not associated with additional costs, selective p...
- Src tyrosine kinase phosphorylation of nuclear receptor HNF4 alpha correlates with isoform-specific loss of HNF4 alpha in human colon cancer
[作者:Chellappa, K; Jankova, L; Schnabl, JM; Pan, SQ; Brelivet, Y; Fung, CLS; Chan, C; Dent, OF; Clarke, SJ; Robertson, GR; Sladek, FM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:2302-2307 , 文章类型: Article,,卷期:2012年109-7]
- Src tyrosine kinase has long been implicated in colon cancer but much remains to be learned about its substrates. The nuclear receptor hepatocyte nuclear factor 4 alpha (HNF4 alpha) has just recently been implicated in c...
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