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  • Detecting Novel Associations in Large Data Sets
    [作者:Reshef, DN; Reshef, YA; Finucane, HK; Grossman, SR; McVean, G; Turnbaugh, PJ; Lander, ES; Mitzenmacher, M; Sabeti, PC,期刊:Science, 页码:1518-1524 , 文章类型: Article,,卷期:2011年334-6062]
  • Identifying interesting relationships between pairs of variables in large data sets is increasingly important. Here, we present a measure of dependence for two-variable relationships: the maximal information coefficient ...
  • The Structure of the Eukaryotic Ribosome at 3.0 angstrom Resolution
    [作者:Ben-Shem, A; de Loubresse, NG; Melnikov, S; Jenner, L; Yusupova, G; Yusupov, M,期刊:Science, 页码:1524-1529 , 文章类型: Article,,卷期:2011年334-6062]
  • Ribosomes translate genetic information encoded by messenger RNA into proteins. Many aspects of translation and its regulation are specific to eukaryotes, whose ribosomes are much larger and intricate than their bacteria...
  • A Coherent Signature of Anthropogenic Nitrogen Deposition to Remote Watersheds of the Northern Hemisphere
    [作者:Holtgrieve, GW; Schindler, DE; Hobbs, WO; Leavitt, PR; Ward, EJ; Bunting, L; Chen, GJ; Finney, BP; Gregory-Eaves, I; Holmgren, S; Lisac, MJ; Lisi, PJ; Nydick, K; Rogers, LA; Saros, JE; Selbie, DT; Shapley, MD; Walsh, PB; Wolfe, AP,期刊:Science, 页码:1545-1548 , 文章类型: Article,,卷期:2011年334-6062]
  • Humans have more than doubled the amount of reactive nitrogen (Nr) added to the biosphere, yet most of what is known about its accumulation and ecological effects is derived from studies of heavily populated regions. Nit...
  • The Tricarboxylic Acid Cycle in Cyanobacteria
    [作者:Zhang, SY; Bryant, DA,期刊:Science, 页码:1551-1553 , 文章类型: Article,,卷期:2011年334-6062]
  • It is generally accepted that cyanobacteria have an incomplete tricarboxylic acid (TCA) cycle because they lack 2-oxoglutarate dehydrogenase and thus cannot convert 2-oxoglutarate to succinyl-coenzyme A (CoA). Genes enco...
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