- Intestinal Microbiota Promote Enteric Virus Replication and Systemic Pathogenesis
[作者:Kuss, SK; Best, GT; Etheredge, CA; Pruijssers, AJ; Frierson, JM; Hooper, LV; Dermody, TS; Pfeiffer, JK,期刊:Science, 页码:249-252 , 文章类型: Article,,卷期:2011年334-6053]
- Intestinal bacteria aid host health and limit bacterial pathogen colonization. However, the influence of bacteria on enteric viruses is largely unknown. We depleted the intestinal microbiota of mice with antibiotics befo...
- MED12, the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas
[作者:Makinen, N; Mehine, M; Tolvanen, J; Kaasinen, E; Li, YL; Lehtonen, HJ; Gentile, M; Yan, J; Enge, M; Taipale, M; Aavikko, M; Katainen, R; Virolainen, E; Bohling, T; Koski, TA; Launonen, V; Sjoberg, J; Taipale, J; Vahteristo, P; Aaltonen, LA,期刊:Science, 页码:252-255 , 文章类型: Article,,卷期:2011年334-6053]
- Uterine leiomyomas, or fibroids, are benign tumors that affect millions of women worldwide and that can cause considerable morbidity. To study the genetic basis of this tumor type, we examined 18 uterine leiomyomas deriv...
- The Antibacterial Lectin RegIII gamma Promotes the Spatial Segregation of Microbiota and Host in the Intestine
[作者:Vaishnava, S; Yamamoto, M; Severson, KM; Ruhn, KA; Yu, XF; Koren, O; Ley, R; Wakeland, EK; Hooper, LV,期刊:Science, 页码:255-258 , 文章类型: Article,,卷期:2011年334-6053]
- The mammalian intestine is home to similar to 100 trillion bacteria that perform important metabolic functions for their hosts. The proximity of vast numbers of bacteria to host intestinal tissues raises the question of ...
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