- Antagonists Induce a Conformational Change in cIAP1 That Promotes Autoubiquitination
[作者:Dueber, EC; Schoeffler, AJ; Lingel, A; Elliott, JM; Fedorova, AV; Giannetti, AM; Zobel, K; Maurer, B; Varfolomeev, E; Wu, P; Wallweber, HJA; Hymowitz, SG; Deshayes, K; Vucic, D; Fairbrother, WJ,期刊:Science, 页码:376-380 , 文章类型: Article,,卷期:2011年334-6054]
- Inhibitor of apoptosis (IAP) proteins are negative regulators of cell death. IAP family members contain RING domains that impart E3 ubiquitin ligase activity. Binding of endogenous or small-molecule antagonists to select...
- Mass Spectrometry of Intact V-Type ATPases Reveals Bound Lipids and the Effects of Nucleotide Binding
[作者:Zhou, M; Morgner, N; Barrera, NP; Politis, A; Isaacson, SC; Matak-Vinkovic, D; Murata, T; Bernal, RA; Stock, D; Robinson, CV,期刊:Science, 页码:380-385 , 文章类型: Article,,卷期:2011年334-6054]
- The ability of electrospray to propel large viruses into a mass spectrometer is established and is rationalized by analogy to the atmospheric transmission of the common cold. Much less clear is the fate of membrane-embed...
- Cerebellum Shapes Hippocampal Spatial Code
[作者:Rochefort, C; Arabo, A; Andre, M; Poucet, B; Save, E; Rondi-Reig, L,期刊:Science, 页码:385-389 , 文章类型: Article,,卷期:2011年334-6054]
- Spatial representation is an active process that requires complex multimodal integration from a large interacting network of cortical and subcortical structures. We sought to determine the role of cerebellar protein kina...
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