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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共59条记录   Activation of the Receptor NKG2D Leads to Production of Th17 Cytokines in CD4(+) T Cells of Patients With Crohn's Disease [作者：Pariente, B; Mocan, I; Camus, M; Dutertre, CA; Ettersperger, J; Cattan, P; Gornet, JM; Dulphy, N; Charron, D; Lemann, M; Toubert, A; Allez, M,期刊：Gastroenterology, 页码：217-U301 , 文章类型： Article，,卷期：2011年141-1] BACKGROUND & AIMS: The natural killer group 2 member D (NKG2D) is a stimulatory receptor expressed on a subset of mucosal and peripheral CD4(+) T cells in patients with Crohn's disease (CD) and other inflammatory disease... Interactions Between Ferroportin and Hephaestin in Rat Enterocytes Are Reduced After Iron Ingestion [作者：Yeh, KY; Yeh, M; Glass, J,期刊：Gastroenterology, 页码：292-U391 , 文章类型： Article，,卷期：2011年141-1] BACKGROUND & AIMS: Ferroportin (Fpn) is a multiple transmembrane protein required for iron export into the systemic circulation, in cooperation with hephaestin (Heph). Despite the importance of Fpn in iron transport, the... Reduced Expression of Ferroportin-1 Mediates Hyporesponsiveness of Suckling Rats to Stimuli That Reduce Iron Absorption [作者：Darshan, D; Wilkins, SJ; Frazer, DM; Anderson, GJ,期刊：Gastroenterology, 页码：300-309 , 文章类型： Article，,卷期：2011年141-1] BACKGROUND & AIMS: Suckling mammals absorb high levels of iron to support their rapid growth. In adults, iron absorption is controlled by systemic signals that alter expression of the iron-regulatory hormone hepcidin. We... Successful Implantation of Bioengineered, Intrinsically Innervated, Human Internal Anal Sphincter [作者：Raghavan, S; Gilmont, RR; Miyasaka, EA; Somara, S; Srinivasan, S; Teitelbaum, DH; Bitar, KN,期刊：Gastroenterology, 页码：310-319 , 文章类型： Article，,卷期：2011年141-1] BACKGROUND & AIMS: To restore fecal continence, the weakened pressure of the internal anal sphincter (IAS) must be increased. We bioengineered intrinsically innervated human IAS to emulate sphincteric physiology in vitro... A Polymorphism in IL28B Distinguishes Exposed, Uninfected Individuals From Spontaneous Resolvers of HCV Infection [作者：Knapp, S; Warshow, U; Ho, KMA; Hegazy, D; Little, AM; Fowell, A; Alexander, G; Thursz, M; Cramp, M; Khakoo, SI,期刊：Gastroenterology, 页码：320-U419 , 文章类型： Article，,卷期：2011年141-1] BACKGROUND & AIMS: Polymorphisms in the interleukin-28B (IL28B) gene are associated with outcomes from infection with hepatitis C virus (HCV). However, the role of these polymorphisms in protecting injection drug users w... The Promoter of Human Telomerase Reverse Transcriptase Is Activated During Liver Regeneration and Hepatocyte Proliferation [作者：Sirma, H; Kumar, M; Meena, JK; Witt, B; Weise, JM; Lechel, A; Ande, S; Sakk, V; Guguen-Guillouzo, C; Zender, L; Rudolph, KL; Gunes, C,期刊：Gastroenterology, 页码：326-U434 , 文章类型： Article，,卷期：2011年141-1] BACKGROUND & AIMS: Telomerase activity has not been detected in healthy human liver biopsy samples, but it is up-regulated in most human liver tumors. It is not clear whether telomerase is activated in response to acute ... Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles [作者：Lucena, MI; Molokhia, M; Shen, YF; Urban, TJ; Aithal, GP; Andrade, RJ; Day, CP; Ruiz-Cabello, F; Donaldson, PT; Stephens, C; Pirmohamed, M; Romero-Gomez, M; Navarro, JM; Fontana, RJ; Miller, M; Groome, M; Bondon-Guitton, E; Conforti, A; Stricker, BHC; Carvajal, A; Ibanez, L; Yue, QY; Eichelbaum, M; Floratos, A; Pe'er, I; Daly, MJ; Goldstein, DB; Dillon, JF; Nelson, MR; Watkins, PB; Daly, AK,期刊：Gastroenterology, 页码：338-347 , 文章类型： Article，,卷期：2011年141-1] BACKGROUND & AIMS: Drug-induced liver injury (DILI), especially from antimicrobial agents, is an important cause of serious liver disease. Amoxicillin-clavulanate (AC) is a leading cause of idiosyncratic DILI, but little... Inflammation Promotes the Loss of Adeno-Associated Virus-Mediated Transgene Expression in Mouse Liver [作者：Breous, E; Somanathan, S; Bell, P; Wilson, JM,期刊：Gastroenterology, 页码：348-U457 , 文章类型： Article，,卷期：2011年141-1] BACKGROUND & AIMS: Non-self transgenes delivered to mouse liver via adeno-associated virus (AAV) are expressed stably due to the induction of immune tolerance. However, such transgene expression has been reported to be l... TLR9 and the NLRP3 Inflammasome Link Acinar Cell Death With Inflammation in Acute Pancreatitis [作者：Hoque, R; Sohail, M; Malik, A; Sarwar, S; Luo, YH; Shah, A; Barrat, F; Flavell, R; Gorelick, F; Husain, S; Mehal, W,期刊：Gastroenterology, 页码：358-369 , 文章类型： Article，,卷期：2011年141-1] BACKGROUND & AIMS: Acute pancreatitis is characterized by early activation of intracellular proteases followed by acinar cell death and inflammation. Activation of damage-associated molecular pattern (DAMP) receptors and... Nerve Growth Factor Modulates TRPV1 Expression and Function and Mediates Pain in Chronic Pancreatitis [作者：Zhu, YH; Colak, T; Shenoy, M; Liu, LS; Pai, R; Li, CP; Mehta, K; Pasricha, PJ,期刊：Gastroenterology, 页码：370-377 , 文章类型： Article，,卷期：2011年141-1] BACKGROUND & AIMS: The pathogenesis of pain in chronic pancreatitis (CP) is poorly understood and treatment remains difficult. We hypothesized that nerve growth factor (NGF) plays a key role in this process via its effec... A Mouse Model of Cholestasis-Associated Cholangiocarcinoma and Transcription Factors Involved in Progression [作者：Yang, HP; Li, TWH; Peng, J; Tang, XL; Ko, KS; Xia, M; Aller, MA,期刊：Gastroenterology, 页码：378-U492 , 文章类型： Article，,卷期：2011年141-1] BACKGROUND & AIMS: Cholestasis contributes to hepatocellular injury and promotes liver carcinogenesis. We created a mouse model of chronic cholestasis to study its effects on progression of cholangiocarcinoma and the onc...