The combination of fullerenes and mechanically interlocked molecular architectures has opened up a new field of research. A selection of representative examples of mechanically interlocked molecules functionalised with f...
Lactams are an important class of compounds owing to their presence in numerous biologically active molecules of natural and unnatural nature. They are also highly versatile intermediates that can be elaborated into inte...
Interaction of apohemoprotein with a covalently immobilized heme moiety onto a gold nanoparticle surface resulted in supramolecular hemoprotein-gold nanoparticle conjugates. The addition of an apohemoprotein dimer furthe...
The covalent functionalization of the external wall of C-60@SWCNT peapods, by in situ generated aryl diazonium salts, assisted by microwave irradiation is reported. Spectroscopic, thermal and microscopy characterization ...
The use of [(IPr)AuOH] permits the generation of gold(I)-amine complexes by a silver-free protocol. These in situ or well-defined complexes are used in a straightforward synthetic route to substituted allenes from propar...
A library of triazole-based telomeric quadruplex-selective ligands has been developed that mimic an established family of tri-substituted acridine-based ligands, using crystal structure data as a starting-point for compu...
Statistical correlation of mass spectrum peak broadening with product dispersity in protein conjugation reactions allows more detailed characterization of putative therapeutic conjugates.
Self-assembled nanohybrids of a 1,10-phenanthroline derivative and Au nanoparticles exhibit different optoelectronic properties, as a consequence of the different arrangements of the nanoparticles on the surface of the d...
We present for the first time a peculiar concentration effect on competitive adsorption of a binary mixture at the liquid/solid interface, which we attribute to the existence of pseudopolymorphism and its concentration d...
A newly synthesized chromophore-modified curdlan functions as a saccharide chemosensor in aqueous solution, enabling us to discriminate tetrasaccharide acarbose from 24 mono-, di-, tri-, and tetrasaccharides.
Well-defined voltammetric current peaks of polyaniline were observed at biosensors hybridized with ruthenium oxide nanoparticle-tagged microRNAs and incubated in a mixture of aniline/H2O2, which can be used for direct mi...
Selective colorimetric detection of ATP in physiological conditions by a Zn(II)-based receptor is reported. This reagent was found to be non-toxic to the living cells and could be used for studying the growth of the yeas...
The fatal neurological disorder Alzheimer's disease has been linked to soluble neurotoxic oligomers of amyloid-beta (A beta) peptides. Herein we demonstrate that Cu1+ ligated within A beta(42) oligomers (Ab sequence: DAE...
A new molecular dynamics simulation method was successfully applied to construct a homogeneous organic-inorganic hybrid silica membrane using the hybrid-pcff (h-pcff) potential function. Analysis suggested that the hybri...
Reaction between EuCl2 and 2,2'-bipyrimidine (bpm) in de-oxygenated water afforded a cationic molecular complex [EuCl(bpm)(2)(H2O)(4)][Cl]center dot H2O (1). When performed in an organic solvent such as THF or methanol, ...
A novel QD-peptide complex for detecting HIV-1 protease activity was prepared from simple one step electrostatic interaction. Fluorescence recovery of the pre-quenched QD through fluorescence resonance energy transfer al...