- Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection
[作者:Brockman, MA; Brumme, ZL; Brumme, CJ; Miura, T; Sela, J; Rosato, PC; Kadie, CM; Carlson, JM; Markle, TJ; Streeck, H; Kelleher, AD; Markowitz, M; Jessen, H; Rosenberg, E; Altfeld, M; Harrigan, PR; Heckerman, D; Walker, BD; Allen, TM,期刊:Journal of virology, 页码:11937-11949 , 文章类型: Article,,卷期:2010年84-22]
- Mutations that allow escape from CD8 T-cell responses are common in HIV-1 and may attenuate pathogenesis by reducing viral fitness. While this has been demonstrated for individual cases, a systematic investigation of the...
- A Live Attenuated H7N7 Candidate Vaccine Virus Induces Neutralizing Antibody That Confers Protection from Challenge in Mice, Ferrets, and Monkeys
[作者:Min, JY; Vogel, L; Matsuoka, Y; Lu, B; Swayne, D; Jin, H; Kemble, G; Subbarao, K,期刊:Journal of virology, 页码:11950-11960 , 文章类型: Article,,卷期:2010年84-22]
- A live attenuated H7N7 candidate vaccine virus was generated by reverse genetics using the modified hemagglutinin (HA) and neuraminidase (NA) genes of highly pathogenic (HP) A/Netherlands/219/03 (NL/03) (H7N7) wild-type ...
|