- Interactive Roles of Ets-1, Sp1, and Acetylated Histones in the Retinoic Acid-dependent Activation of Guanylyl Cyclase/Atrial Natriuretic Peptide Receptor-A Gene Transcription
[作者:Kumar, P; Garg, R; Bolden, G; Pandey, KN,期刊:Journal of Biological Chemistry, 页码:37521-37530 , 文章类型: Article,,卷期:2010年285-48]
- Cardiac hormones atrial and brain natriuretic peptides activate guanylyl cyclase/natriuretic peptide receptor-A (GC-A/NPRA), which plays a critical role in reduction of blood pressure and blood volume. Currently, the mec...
- CD23 Sheddase A Disintegrin and Metalloproteinase 10 (ADAM10) Is Also Required for CD23 Sorting into B Cell-derived Exosomes
[作者:Mathews, JA; Gibb, DR; Chen, BH; Scherle, P; Conrad, DH,期刊:Journal of Biological Chemistry, 页码:37531-37541 , 文章类型: Article,,卷期:2010年285-48]
- The low affinity receptor for IgE, CD23, is the natural regulator of IgE synthesis, and understanding both the synthesis and the catabolism of CD23 are, thus, important issues. Membrane CD23 is cleaved by a disintegrin a...
- CpeS Is a Lyase Specific for Attachment of 3Z-PEB to Cys(82) of beta-phycoerythrin from Prochlorococcus marinus MED4
[作者:Wiethaus, J; Busch, AWU; Kock, K; Leichert, LI; Herrmann, C; Frankenberg-Dinkel, N,期刊:Journal of Biological Chemistry, 页码:37561-37569 , 文章类型: Article,,卷期:2010年285-48]
- In contrast to the majority of cyanobacteria, the unicellular marine cyanobacterium Prochlorococcus marinus MED4 uses an intrinsic divinyl-chlorophyll-dependent light-harvesting system for photosynthesis. Despite the abs...
- Ure2 Is Involved in Nitrogen Catabolite Repression and Salt Tolerance via Ca2+ Homeostasis and Calcineurin Activation in the Yeast Hansenula polymorpha
[作者:Rodriguez, C; Tejera, P; Medina, B; Guillen, R; Dominguez, A; Ramos, J; Siverio, JM,期刊:Journal of Biological Chemistry, 页码:37551-37560 , 文章类型: Article,,卷期:2010年285-48]
- Disruption of HpURE2 resulted in a low expression of genes encoding nitrate-assimilatory proteins; sensitivity to Li+, Na+, and Cd2+; no induction of ENA1; low levels of the GATA-type transcription factor Gat1; and low i...
- TRIF Mediates Toll-like Receptor 5-induced Signaling in Intestinal Epithelial Cells
[作者:Choi, YJ; Im, E; Chung, HK; Pothoulakis, C; Rhee, SH,期刊:Journal of Biological Chemistry, 页码:37570-37578 , 文章类型: Article,,卷期:2010年285-48]
- Toll-like receptors (TLRs) associate with adaptor molecules (MyD88, Mal/TIRAP, TRAM, and TRIF) to mediate signaling of host-microbial interaction. For instance, TLR4 utilizes the combination of both Mal/TIRAP-MyD88 (MyD8...
- Leptin Receptor (Lepr) Is a Negative Modulator of Bone Mechanosensitivity and Genetic Variations in Lepr May Contribute to the Differential Osteogenic Response to Mechanical Stimulation in the C57BL/6J and C3H/HeJ Pair of Mouse Strains
[作者:Kapur, S; Amoui, M; Kesavan, C; Wang, XG; Mohan, S; Baylink, DJ; Lau, KHW,期刊:Journal of Biological Chemistry, 页码:37607-37618 , 文章类型: Article,,卷期:2010年285-48]
- This study investigated the role of leptin receptor (Lepr) signaling in determining the bone mechanosensitivity and also evaluated whether differences in the Lepr signaling may contribute to the differential osteogenic r...
- Role of Glycosaminoglycan Sulfation in the Formation of Immunoglobulin Light Chain Amyloid Oligomers and Fibrils
[作者:Ren, RY; Hong, ZN; Gong, HY; Laporte, K; Skinner, M; Seldin, DC; Costello, CE; Connors, LH; Trinkaus-Randall, V,期刊:Journal of Biological Chemistry, 页码:37672-37682 , 文章类型: Article,,卷期:2010年285-48]
- Primary amyloidosis (AL) results from overproduction of unstable monoclonal immunoglobulin light chains (LCs) and the deposition of insoluble fibrils in tissues, leading to fatal organ disease. Glycosaminoglycans (GAGs) ...
- Core2 O-Glycan Structure Is Essential for the Cell Surface Expression of Sucrase Isomaltase and Dipeptidyl Peptidase-IV during Intestinal Cell Differentiation
[作者:Lee, SH; Yu, SY; Nakayama, J; Khoo, KH; Stone, EL; Fukuda, MN; Marth, JD; Fukuda, M,期刊:Journal of Biological Chemistry, 页码:37683-37692 , 文章类型: Article,,卷期:2010年285-48]
- Alterations in glycosylation play an important role during intestinal cell differentiation. Here, we compared expression of mucin-type O-glycan synthases from proliferating and differentiated HT-29 and Caco-2 cells. Muci...
- The Novel PMCA2 Pump Mutation Tommy Impairs Cytosolic Calcium Clearance in Hair Cells and Links to Deafness in Mice
[作者:Bortolozzi, M; Brini, M; Parkinson, N; Crispino, G; Scimemi, P; De Siati, RD; Di Leva, F; Parker, A; Ortolano, S; Arslan, E; Brown, SD; Carafoli, E; Mammano, F,期刊:Journal of Biological Chemistry, 页码:37693-37703 , 文章类型: Article,,卷期:2010年285-48]
- The mechanotransduction process in hair cells in the inner ear is associated with the influx of calcium from the endolymph. Calcium is exported back to the endolymph via the splice variant w/a of the PMCA2 of the stereoc...
- A Novel p53 Phosphorylation Site within the MDM2 Ubiquitination Signal II. A MODEL IN WHICH PHOSPHORYLATION AT SER269 INDUCES A MUTANT CONFORMATION TO p53
[作者:Fraser, JA; Madhumalar, A; Blackburn, E; Bramham, J; Walkinshaw, MD; Verma, C; Hupp, TR,期刊:Journal of Biological Chemistry, 页码:37773-37786 , 文章类型: Article,,卷期:2010年285-48]
- The p53 DNA-binding domain harbors a conformationally flexible multiprotein binding site that regulates p53 ubiquitination. A novel phosphorylation site exists within this region at Ser(269), whose phosphomimetic mutatio...
- Identification of the Drosophila Ortholog of HSPB8 IMPLICATION OF HSPB8 LOSS OF FUNCTION IN PROTEIN FOLDING DISEASES
[作者:Carra, S; Boncoraglio, A; Kanon, B; Brunsting, JF; Minoia, M; Rana, A; Vos, MJ; Seidel, K; Sibon, OCM; Kampinga, HH,期刊:Journal of Biological Chemistry, 页码:37811-37822 , 文章类型: Article,,卷期:2010年285-48]
- Protein aggregation is a hallmark of many neuronal disorders, including the polyglutamine disorder spinocerebellar ataxia 3 and peripheral neuropathies associated with the K141E and K141N mutations in the small heat shoc...
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