- A 4-Gene Signature Predicts Survival of Patients With Resected Adenocarcinoma of the Esophagus, Junction, and Gastric Cardia
[作者：Peters, CJ; Rees, JRE; Hardwick, RH; Hardwick, JS; Vowler, SL; Ong, CAJ; Zhang, CS; Save, V; O'Donovan, M; Rassl, D; Alderson, D; Caldas, C; Fitzgerald, RC,期刊：Gastroenterology, 页码：1995-U280 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: The incidence of esophageal and junctional adenocarcinoma has increased 6-fold in the past 30 years and 5-year survival remains approximately 20%. Current staging is limited in its ability to predict s...
- Helicobacter pylori Infection Promotes Methylation and Silencing of Trefoil Factor 2, Leading to Gastric Tumor Development in Mice and Humans
[作者：Peterson, AJ; Menheniott, TR; O'Connor, L; Walduck, AK; Fox, JG; Kawakami, K; Minamoto, T; Ong, EK; Wang, TC; Judd, LM; Giraud, AS,期刊：Gastroenterology, 页码：2005-2017 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Trefoil factors (TFFs) regulate mucosal repair and suppress tumor formation in the stomach. Tff1 deficiency results in gastric cancer, whereas Tff2 deficiency increases gastric inflammation. TFF2 expre...
- Mature Chief Cells Are Cryptic Progenitors for Metaplasia in the Stomach
[作者：Nam, KT; Lee, HJ; Sousa, JF; Weis, VG; O'Neal, RL; Finke, PE; Romero-Gallo, J; Shi, GL; Mills, JC; Peek, RM; Konieczny, SF; Goldenring, JR,期刊：Gastroenterology, 页码：2028-U324 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Gastric cancer evolves in the setting of a pathologic mucosal milieu characterized by both loss of acid-secreting parietal cells and mucous cell metaplasias. Indeed, mucous cell metaplasia is considere...
- XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic Reticulum
[作者：Huh, WJ; Esen, E; Geahlen, JH; Bredemeyer, AJ; Lee, AH; Shi, GL; Konieczny, SF; Glimcher, LH; Mills, JC,期刊：Gastroenterology, 页码：2038-2049 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: The transition of gastric epithelial mucous neck cells (NCs) to digestive enzyme-secreting zymogenic cells (ZCs) involves an increase in rough endoplasmic reticulum (ER) and formation of many large sec...
- Bone Morphogenetic Protein Signaling Regulates Gastric Epithelial Cell Development and Proliferation in Mice
[作者：Shinohara, M; Mao, M; Keeley, TM; El-Zaatari, M; Lee, HJ; Eaton, KA; Samuelson, LC; Merchant, JL; Goldenring, JR; Todisco, A,期刊：Gastroenterology, 页码：2050-U349 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: We investigated the role of bone morphogenetic protein (BMP) signaling in the regulation of gastric epithelial cell growth and differentiation by generating transgenic mice that express the BMP inhibit...
- Intracellular Calcium Release and Protein Kinase C Activation Stimulate Sonic Hedgehog Gene Expression During Gastric Acid Secretion
[作者：El-Zaatari, M; Zavros, Y; Tessier, A; Waghray, M; Lentz, S; Gumucio, D; Todisco, A; Merchant, JL,期刊：Gastroenterology, 页码：2061-U362 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Hypochlorhydria during Helicobacter pylori infection inhibits gastric Sonic Hedgehog (Shh) expression. We investigated whether acid-secretory mechanisms regulate Shh gene expression through intracellul...
- Characterization of the Intestinal Cancer Stem Cell Marker CD166 in the Human and Mouse Gastrointestinal Tract
[作者：Levin, TG; Powell, AE; Davies, PS; Silk, AD; Dismuke, AD; Anderson, EC; Swain, JR; Wong, MH,期刊：Gastroenterology, 页码：2072-U378 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: CD166 (also called activated leukocyte cell adhesion molecule [ALCAM]) is a marker of colorectal cancer (CRC) stem cells; it is expressed by aggressive tumors. Although the presence of CD166 at the tum...
- Corticotropin-Releasing Factor Regulates TLR4 Expression in the Colon and Protects Mice From Colitis
[作者：Chaniotou, Z; Giannogonas, P; Theoharis, S; Teli, T; Gay, J; Savidge, T; Koutmani, Y; Brugni, J; Kokkotou, E; Pothoulakis, C; Karalis, KP,期刊：Gastroenterology, 页码：2083-2092 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Defects in the colonic innate immune response have been associated with inflammatory bowel disease (IBD). Corticotropin-releasing hormone (CRH, or corticotropin-releasing factor [CRF]) is a neuropeptid...
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