- Silencing of hsa-miR-124 by EVI1 in cell lines and patients with acute myeloid leukemia
[作者：Vazquez, I; Maicas, M; Marcotegui, N; Conchillo, A; Guruceaga, E; Roman-Gomez, J; Calasanz, MJ; Agirre, X; Prosper, F; Odero, MD,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：E167-E168 , 文章类型： Letter，,卷期：2010年107-44]
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- Teichoic acids are temporal and spatial regulators of peptidoglycan cross-linking in Staphylococcus aureus
[作者：Atilano, ML; Pereira, PM; Yates, J; Reed, P; Veiga, H; Pinho, MG; Filipe, SR,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：18991-18996 , 文章类型： Article，,卷期：2010年107-44]
- The cell wall of Staphylococcus aureus is characterized by an extremely high degree of cross-linking within its peptidoglycan (PGN). Penicillin-binding protein 4 (PBP4) is required for the synthesis of this highly cross-...
- Inhibition of pathogen-induced apoptosis by a Coxiella burnetii type IV effector protein
[作者：Luhrmann, A; Nogueira, CV; Carey, KL; Roy, CR,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：18997-19001 , 文章类型： Article，,卷期：2010年107-44]
Coxiella burnetii and Legionella pneumophila are evolutionarily related pathogens with different intracellular infection strategies. C. burnetii persists within and is transmitted by mammalian hosts, whereas, L. pneum...
- Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins
[作者：Rivera, J; Cordero, RJB; Nakouzi, AS; Frases, S; Nicola, A; Casadevall, A,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：19002-19007 , 文章类型： Article，,卷期：2010年107-44]
- Extracellular vesicle production is a ubiquitous process in Gram-negative bacteria, but little is known about such process in Gram-positive bacteria. We report the isolation of extracellular vesicles from the supernatant...
- Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model
[作者：Zhang, YF; Kurup, P; Xu, JA; Carty, N; Fernandez, SM; Nygaard, HB; Pittenger, C; Greengard, P; Strittmatter, SM; Nairn, AC; Lombroso, PJ,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：19014-19019 , 文章类型： Article，,卷期：2010年107-44]
- Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disorder. Early in the pathophysiology of AD, synaptic function is disrupted by soluble A beta oligomers, possibly through A beta-mediated interna...
- A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery
[作者：Neufeld-Cohen, A; Tsoory, MM; Evans, AK; Getselter, D; Gil, S; Lowry, CA; Vale, WW; Chen, A,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：19020-19025 , 文章类型： Article，,卷期：2010年107-44]
- Responding to stressful events requires numerous adaptive actions involving integrated changes in the central nervous and neuroendocrine systems. Numerous studies have implicated dysregulation of stress-response mechanis...
- Constitutively active H-ras accelerates multiple forms of plasticity in developing visual cortex
[作者：Kaneko, M; Cheetham, CE; Lee, YS; Silva, AJ; Stryker, MP; Fox, K,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：19026-19031 , 文章类型： Article，,卷期：2010年107-44]
- Experience-dependent cortical plasticity has been studied by using loss-of-function methods. Here, we take the complementary approach of using a genetic gain-of-function that enhances plasticity. We show that a constitut...
- Push-and-pull regulation of the fusion pore by synaptotagmin-7
[作者：Segovia, M; Ales, E; Montes, MA; Bonifas, I; Jemal, I; Lindau, M; Maximov, A; Sudhof, TC; de Toledo, GA,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：19032-19037 , 文章类型： Article，,卷期：2010年107-44]
- In chromaffin cells, Ca2+ binding to synaptotagmin-1 and -7 triggers exocytosis by promoting fusion pore opening and fusion pore expansion. Synaptotagmins contain two C2 domains that both bind Ca2+ and contribute to exoc...
- Role of the hippocampus in remembering the past and imagining the future
[作者：Squire, LR; van der Horst, AS; McDuff, SGR; Frascino, JC; Hopkins, RO; Mauldin, KN,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：19044-19048 , 文章类型： Article，,卷期：2010年107-44]
- It has been proposed that a core network of brain regions, including the hippocampus, supports both past remembering and future imagining. We investigated the importance of the hippocampus for these functions. Five patie...
- Divergent and nonuniform gene expression patterns in mouse brain
[作者：Morris, JA; Royall, JJ; Bertagnolli, D; Boe, AF; Burnell, JJ; Byrnes, EJ; Copeland, C; Desta, T; Fischer, SR; Goldy, J; Glattfelder, KJ; Kidney, JM; Lemon, T; Orta, GJ; Parry, SE; Pathak, SD; Pearson, OC; Reding, M; Shapouri, S; Smith, KA; Soden, C; Solan, BM; Weller, J; Takahashi, JS; Overly, CC; Lein, ES; Hawrylycz, MJ; Hohmann, JG; Jones, AR,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：19049-19054 , 文章类型： Article，,卷期：2010年107-44]
- Considerable progress has been made in understanding variations in gene sequence and expression level associated with phenotype, yet how genetic diversity translates into complex phenotypic differences remains poorly und...
- Endosomal sorting of readily releasable synaptic vesicles
[作者：Hoopmann, P; Punge, A; Barysch, SV; Westphal, V; Buckers, J; Opazo, F; Bethani, I; Lauterbach, MA; Hell, SW; Rizzoli, SO,期刊：Proceedings of the National Academy of Sciences of the United States of America, 页码：19055-19060 , 文章类型： Article，,卷期：2010年107-44]
- Neurotransmitter release is achieved through the fusion of synaptic vesicles with the neuronal plasma membrane (exocytosis). Vesicles are then retrieved from the plasma membrane (endocytosis). It was hypothesized more th...
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