- Dominant Negative Mutants of the Murine Cytomegalovirus M53 Gene Block Nuclear Egress and Inhibit Capsid Maturation
[作者:Popa, M; Ruzsics, Z; Lotzerich, M; Dolken, L; Buser, C; Walther, P; Koszinowski, UH,期刊:Journal of virology, 页码:9035-9046 , 文章类型: Article,,卷期:2010年84-18]
- The alphaherpesvirus proteins UL31 and UL34 and their homologues in other herpesvirus subfamilies cooperate at the nuclear membrane in the export of nascent herpesvirus capsids. We studied the respective betaherpesvirus ...
- Inhibition of Encephalomyocarditis Virus and Poliovirus Replication by Quinacrine: Implications for the Design and Discovery of Novel Antiviral Drugs
[作者:Gasparian, AV; Neznanov, N; Jha, S; Galkin, O; Moran, JJ; Gudkov, AV; Gurova, KV; Komar, AA,期刊:Journal of virology, 页码:9390-9397 , 文章类型: Article,,卷期:2010年84-18]
- The 9-aminoacridine (9AA) derivative quinacrine (QC) has a long history of safe human use as an anti-protozoal and antirheumatic agent. QC intercalates into DNA and RNA and can inhibit DNA replication, RNA transcription,...
- Human Enterovirus 109: a Novel Interspecies Recombinant Enterovirus Isolated from a Case of Acute Pediatric Respiratory Illness in Nicaragua
[作者:Yozwiak, NL; Skewes-Cox, P; Gordon, A; Saborio, S; Kuan, G; Balmaseda, A; Ganem, D; Harris, E; DeRisi, JL,期刊:Journal of virology, 页码:9047-9058 , 文章类型: Article,,卷期:2010年84-18]
- Enteroviruses (Picornaviridae family) are a common cause of human illness worldwide and are associated with diverse clinical syndromes, including asymptomatic infection, respiratory illness, gastroenteritis, and meningit...
- Release of Genotype 1 Hepatitis E Virus from Cultured Hepatoma and Polarized Intestinal Cells Depends on Open Reading Frame 3 Protein and Requires an Intact PXXP Motif
[作者:Emerson, SU; Nguyen, HT; Torian, U; Burke, D; Engle, R; Purcell, RH,期刊:Journal of virology, 页码:9059-9069 , 文章类型: Article,,卷期:2010年84-18]
- Hepatitis E virus genotype 1 strain Sar55 replicated in subcloned Caco-2 intestinal cells and Huh7 hepatoma cells that had been transfected with in vitro transcribed viral genomes, and hepatitis E virions were released i...
- Viral Particles of Endogenous Betaretroviruses Are Released in the Sheep Uterus and Infect the Conceptus Trophectoderm in a Transspecies Embryo Transfer Model
[作者:Black, SG; Arnaud, F; Burghardt, RC; Satterfield, MC; Fleming, JAGW; Long, CR; Hanna, C; Murphy, L; Biek, R; Palmarini, M; Spencer, TE,期刊:Journal of virology, 页码:9078-9085 , 文章类型: Article,,卷期:2010年84-18]
- The sheep genome contains multiple copies of endogenous betaretroviruses highly related to the exogenous and oncogenic jaagsiekte sheep retrovirus (JSRV). The endogenous JSRVs (enJSRVs) are abundantly expressed in the ut...
- Immunization with Wild-Type or CD4-Binding-Defective HIV-1 Env Trimers Reduces Viremia Equivalently following Heterologous Challenge with Simian-Human Immunodeficiency Virus
[作者:Sundling, C; O'Dell, S; Douagi, I; Forsell, MN; Morner, A; Lore, K; Mascola, JR; Wyatt, RT; Hedestam, GBK,期刊:Journal of virology, 页码:9086-9095 , 文章类型: Article,,卷期:2010年84-18]
- We recently reported that rhesus macaques inoculated with CD4-binding-competent and CD4-binding-defective soluble YU2-derived HIV-1 envelope glycoprotein (Env) trimers in adjuvant generate comparable levels of Env-specif...
- Assessing the Viral Fitness of Oseltamivir-Resistant Influenza Viruses in Ferrets, Using a Competitive-Mixtures Model
[作者:Hurt, AC; Nor'e, SS; McCaw, JM; Fryer, HR; Mosse, J; McLean, AR; Barr, IG,期刊:Journal of virology, 页码:9427-9438 , 文章类型: Article,,卷期:2010年84-18]
- To determine the relative fitness of oseltamivir-resistant strains compared to susceptible wild-type viruses, we combined mathematical modeling and statistical techniques with a novel in vivo "competitive-mixtures" exper...
- The Clinically Approved Proteasome Inhibitor PS-341 Efficiently Blocks Influenza A Virus and Vesicular Stomatitis Virus Propagation by Establishing an Antiviral State
[作者:Dudek, SE; Luig, C; Pauli, EK; Schubert, U; Ludwig, S,期刊:Journal of virology, 页码:9439-9451 , 文章类型: Article,,卷期:2010年84-18]
- Recently it has been shown that the proinflammatory NF-kappa B pathway promotes efficient influenza virus propagation. Based on these findings, it was suggested that NF-kappa B blockade may be a promising approach for an...
- Mutational and Metal Binding Analysis of the Endonuclease Domain of the Influenza Virus Polymerase PA Subunit
[作者:Crepin, T; Dias, A; Palencia, A; Swale, C; Cusack, S; Ruigrok, RWH,期刊:Journal of virology, 页码:9096-9104 , 文章类型: Article,,卷期:2010年84-18]
- Influenza virus polymerase initiates the biosynthesis of its own mRNAs with capped 10- to 13-nucleotide fragments cleaved from cellular (pre-)mRNAs. Two activities are required for this cap-snatching activity: specific b...
- High Variability and Rapid Evolution of a Nanovirus
[作者:Grigoras, I; Timchenko, T; Grande-Perez, A; Katul, L; Vetten, HJ; Gronenborn, B,期刊:Journal of virology, 页码:9105-9117 , 文章类型: Article,,卷期:2010年84-18]
- Nanoviruses are multipartite single-stranded DNA (ssDNA) plant viruses that cause important diseases of leguminous crops and banana. Little has been known about the variability and molecular evolution of these viruses. H...
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