- Neutrophil Elastase Contributes to Acute Lung Injury Induced by Bilateral Nephrectomy
[作者:Ishii, T; Doi, K; Okamoto, K; Imamura, M; Dohi, M; Yamamoto, K; Fujita, T; Noiri, E,期刊:American Journal of Pathology, 页码:1665-1673 , 文章类型: Article,,卷期:2010年177-4]
- Acute kidney injury (AKI) is a serious problem in critically ill patients of intensive care units. It has been reported previously that AKI can induce acute lung injury (ALI), as well as cause injuries to other remote or...
- No Haploinsufficiency but Loss of Heterozygosity for EXT in Multiple Osteochondromas
[作者:Reijnders, CMA; Waaijer, CJF; Hamilton, A; Buddingh, EP; Dijkstra, SPD; Ham, J; Bakker, E; Szuhai, K; Karperien, M; Hogendoorn, PCW; Stringer, SE; Bovee, JVMG,期刊:American Journal of Pathology, 页码:1946-1957 , 文章类型: Article,,卷期:2010年177-4]
- Multiple osteochondromas (MO) is an autosomal dominant disorder caused by germline mutations in EXT1 and/or EXT2. In contrast, solitary osteochondroma (SO) is nonhereditary. Products of the EXT gene are involved in hepar...
- A Molecular Profile of Focal Segmental Glomerulosclerosis from Formalin-Fixed, Paraffin-Embedded Tissue
[作者:Hodgin, JB; Borczuk, AC; Nasr, SH; Markowitz, GS; Nair, V; Martini, S; Eichinger, F; Vining, C; Berthier, CC; Kretzler, M; D'Agati, VD,期刊:American Journal of Pathology, 页码:1674-1686 , 文章类型: Article,,卷期:2010年177-4]
- Focal segmental glomerulosclerosis (FSGS) is a common form of idiopathic nephrotic syndrome defined by the characteristic lesions of focal glomerular sclerosis and foot process effacement; however, its etiology and patho...
- tPA Activates LDL Receptor-Related Protein 1-Mediated Mitogenic Signaling Involving the p90RSK and GSK3 beta Pathway
[作者:Lin, L; Bu, GJ; Mars, WM; Reeves, WB; Tanaka, S; Hu, KB,期刊:American Journal of Pathology, 页码:1687-1696 , 文章类型: Article,,卷期:2010年177-4]
- In renal fibrosis, interstitial fibroblasts have an increased proliferative phenotype, and the numbers of interstitial fibroblasts closely correlate with the extent of kidney damage. The mechanisms underlying proliferati...
- Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes
[作者:Perez, CJ; Jaubert, J; Guenet, JL; Bamhart, KF; Ross-Inta, CM; Quintanilla, VC; Aubin, I; Brandon, JL; Otto, NW; DiGiovanni, J; Gimenez-Conti, I; Giulivi, C; Kusewitt, DF; Conti, CJ; Benavides, F,期刊:American Journal of Pathology, 页码:1958-1968 , 文章类型: Article,,卷期:2010年177-4]
- Citrullinemia type I (CTLN1, OMIM# 215700) is an Inherited urea cycle disorder that is caused by an argininosuccinate synthetase (ASS) enzyme deficiency. In this report, we describe two spontaneous hypomorphic alleles of...
- Mice with Inactivation of Aryl Hydrocarbon Receptor-Interacting Protein (Aip) Display Complete Penetrance of Pituitary Adenomas with Aberrant ARNT Expression
[作者:Raitila, A; Lehtonen, HJ; Arola, J; Heliovaara, E; Ahlsten, M; Georgitsi, M; Jalanko, A; Paetau, A; Aaltonen, LA; Karhu, A,期刊:American Journal of Pathology, 页码:1969-1976 , 文章类型: Article,,卷期:2010年177-4]
- Mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene have been shown to predispose to pituitary adenoma predisposition, a condition characterized by growth hormone (GH)-secreting pituitary tumors. To...
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