- Novel quinoline and naphthalene derivatives as potent antimycobacterial agents
[作者:Upadhayaya, RS; Vandavasi, JK; Kardile, RA; Lahore, SV; Dixit, SS; Deokar, HS; Shinde, PD; Sarmah, MP; Chattopadhyaya, J,期刊:European Journal of Medicinal Chemistry, 页码:1854-1867 , 文章类型: Article,,卷期:2010年45-5]
- We have designed and synthesized both the quinoline and naphthalene based molecules influenced by the unique structural make-up of mefloquine and TMC207, respectively. These compounds were evaluated for their anti-mycoba...
- Evaluation of 2-thioxo-2,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidin-4(1H)-one analogues as GAA activators
[作者:Marugan, JJ; Zheng, W; Motabar, O; Southall, N; Goldin, E; Sidransky, E; Aungst, RA; Liu, K; Sadhukhan, SK; Austin, CP,期刊:European Journal of Medicinal Chemistry, 页码:1880-1897 , 文章类型: Article,,卷期:2010年45-5]
- Pompe disease is a lysosomal storage disease (LSD) caused by a deficiency in the lysosomal enzyme acid alpha-glucosidase. In several LSDs, enzyme inhibitors have been used as small molecule chaperones to facilitate and i...
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