- Ablation of the Complementarity-Determining Region H3 Apex of the Anti-HIV-1 Broadly Neutralizing Antibody 2F5 Abrogates Neutralizing Capacity without Affecting Core Epitope Binding
[作者:Julien, JP; Huarte, N; Maeso, R; Taneva, SG; Cunningham, A; Nieva, JL; Pai, EF,期刊:Journal of virology, 页码:4136-4147 , 文章类型: Article,,卷期:2010年84-9]
- The identification and characterization of broadly neutralizing antibodies (bnAbs) against HIV-1 has formed a major research focus, with the ultimate goal to help in the design of an effective AIDS vaccine. One of these ...
- The m74 Gene Product of Murine Cytomegalovirus (MCMV) Is a Functional Homolog of Human CMV gO and Determines the Entry Pathway of MCMV
[作者:Scrivano, L; Esterlechner, J; Muhlbach, H; Ettischer, N; Hagen, C; Grunewald, K; Mohr, CA; Ruzsics, Z; Koszinowski, U; Adler, B,期刊:Journal of virology, 页码:4469-4480 , 文章类型: Article,,卷期:2010年84-9]
- The glycoprotein gO (UL74) of human cytomegalovirus (HCMV) forms a complex with gH/gL. Virus mutants with a deletion of gO show a defect in secondary envelopment with the consequence that virus spread is restricted to a ...
- The Elk-1 and Serum Response Factor Binding Sites in the Major Immediate-Early Promoter of Human Cytomegalovirus Are Required for Efficient Viral Replication in Quiescent Cells and Compensate for Inactivation of the NF-kappa B Sites in Proliferating Cells
[作者:Caposio, P; Luganini, A; Bronzini, M; Landolfo, S; Gribaudo, G,期刊:Journal of virology, 页码:4481-4493 , 文章类型: Article,,卷期:2010年84-9]
- The major immediate-early promoter (MIEP) region of human cytomegalovirus (HCMV) plays a critical role in the regulation of lytic and latent infections by integrating multiple signals supplied by the infecting virus, the...
- Interaction of a Host Protein with Core Complexes of Bacteriophage Phi 6 To Control Transcription
[作者:Qiao, XY; Sun, Y; Qiao, J; Mindich, L,期刊:Journal of virology, 页码:4821-4825 , 文章类型: Article,,卷期:2010年84-9]
- Bacteriophages of the family Cystoviridae have genomes consisting of three double-stranded RNA (dsRNA) segments, L, S, and M, packaged within a polyhedral capsid along with RNA polymerase. Transcription of genomic segmen...
- Inhibition of Human Natural Killer Cell Activity by Influenza Virions and Hemagglutinin
[作者:Mao, HW; Tu, WW; Liu, YP; Qin, G; Zheng, J; Chan, PL; Lam, KT; Peiris, JSM; Lau, YL,期刊:Journal of virology, 页码:4148-4157 , 文章类型: Article,,卷期:2010年84-9]
- Natural killer (NK) cells keep viral infections under control at the early phase by directly killing infected cells. Influenza is an acute contagious respiratory viral disease transmitted from host-to-host in the first f...
- Identification and Characterization of Clevudine-Resistant Mutants of Hepatitis B Virus Isolated from Chronic Hepatitis B Patients
[作者:Kwon, SY; Park, YK; Ahn, SH; Cho, ES; Choe, WH; Lee, CH; Kim, BK; Ko, SY; Choi, HS; Park, ES; Shin, GC; Kim, KH,期刊:Journal of virology, 页码:4494-4503 , 文章类型: Article,,卷期:2010年84-9]
- Clevudine (CLV) is a nucleoside analog with potent antiviral activity against chronic hepatitis B virus (HBV) infection. Viral resistance to CLV in patients receiving CLV therapy has not been reported. The aim of this st...
- Identification of a Dominant Negative Inhibitor of Human Zinc Finger Antiviral Protein Reveals a Functional Endogenous Pool and Critical Homotypic Interactions
[作者:Law, LMJ; Albin, OR; Carroll, JWN; Jones, CT; Rice, CM; MacDonald, MR,期刊:Journal of virology, 页码:4504-4512 , 文章类型: Article,,卷期:2010年84-9]
- The zinc finger antiviral protein (ZAP) is a host factor with potent antiviral activity when overexpressed in cells. ZAP blocks replication of the prototype alphavirus Sindbis virus (SINV) at a step at or before translat...
- Pathogenic Hantaviruses Direct the Adherence of Quiescent Platelets to Infected Endothelial Cells
[作者:Gavrilovskaya, IN; Gorbunova, EE; Mackow, ER,期刊:Journal of virology, 页码:4832-4839 , 文章类型: Article,,卷期:2010年84-9]
- Hantavirus infections are noted for their ability to infect endothelial cells, cause acute thrombocytopenia, and trigger 2 vascular-permeability-based diseases. However, hantavirus infections are not lytic, and the mecha...
- Stimulation of HIV-1 Replication in Immature Dendritic Cells in Contact with Primary CD4 T or B Lymphocytes
[作者:Holl, V; Xu, K; Peressin, M; Lederle, A; Biedma, ME; Delaporte, M; Decoville, T; Schmidt, S; Laumond, G; Aubertin, AM; Moog, C,期刊:Journal of virology, 页码:4172-4182 , 文章类型: Article,,卷期:2010年84-9]
- Sexual transmission is the major route of HIV-1 infection worldwide. Dendritic cells (DCs) from the mucosal layers are considered to be the initial targets of HIV-1 and probably play a crucial role in HIV-1 transmission....
- CD147/EMMPRIN Acts as a Functional Entry Receptor for Measles Virus on Epithelial Cells
[作者:Watanabe, A; Yoneda, M; Ikeda, F; Terao-Muto, Y; Sato, H; Kai, C,期刊:Journal of virology, 页码:4183-4193 , 文章类型: Article,,卷期:2010年84-9]
- Measles is a highly contagious human disease caused by measles virus (MeV) and remains the leading cause of death in children, particularly in developing countries. Wild-type MeV preferentially infects lymphocytes by usi...
|