- Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice
[作者:Hu, ZY; Wang, HL; Lee, IH; Du, J; Mitch, WE,期刊:Journal of clinical investigation, 页码:3059-3069 , 文章类型: Article,,卷期:2009年119-10]
- Muscle wasting is associated with a number of pathophysiologic conditions, including metabolic acidosis, diabetes, sepsis, and high angiotensin H levels. Under these conditions, activation of muscle protein degradation r...
- Evidence of premature immune aging in patients thymectomized during early childhood
[作者:Sauce, D; Larsen, M; Fastenackels, S; Duperrier, A; Keller, M; Grubeck-Loebenstein, B; Ferrand, C; Debre, P; Sidi, D; Appay, V,期刊:Journal of clinical investigation, 页码:3070-3078 , 文章类型: Article,,卷期:2009年119-10]
- While the thymus is known to be essential for the initial production of T cells during early life, its contribution to immune development remains a matter of debate. In fact, during cardiac surgery in newborns, the thymu...
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