- COX-2 and Prostaglandin EP3/EP4 Signaling Regulate the Tumor Stromal Proangiogenic Microenvironment via CXCL12-CXCR4 Chemokine Systems
[作者:Katoh, H; Hosono, K; Ito, Y; Suzuki, T; Ogawa, Y; Kubo, H; Kamata, H; Mishima, T; Tamaki, H; Sakagami, H; Sugimoto, Y; Narumiya, S; Watanabe, M; Majima, M,期刊:American Journal of Pathology, 页码:1469-1483 , 文章类型: Article,,卷期:2010年176-3]
- Bone marrow (BM)-derived hematopoietic cells, which are major components of tumor stroma, determine the tumor microenvironment and regulate tumor phenotypes. Cyclooxygenase (COX)-2 and endogenous prostaglandins are impor...
- ADAMTS9 Is a Cell-Autonomously Acting, Anti-Angiogenic Metalloprotease Expressed by Microvascular Endothelial Cells
[作者:Koo, BH; Coe, DM; Dixon, LJ; Somerville, RPT; Nelson, CM; Wang, LW; Young, ME; Lindner, DJ; Apte, SS,期刊:American Journal of Pathology, 页码:1494-1504 , 文章类型: Article,,卷期:2010年176-3]
- The metalloprotease ADAMTS9 participates in melanoblast development and is a tumor suppressor in esophageal and nasopharyngeal cancer. ADAMTS9 null mice die before gastrulation, but, ADAMTS9(+/-) mice were initially thou...
- Steroid-Resistant Lymphatic Remodeling in Chronically Inflamed Mouse Airways
[作者:Yao, LC; Baluk, P; Feng, J; McDonald, DM,期刊:American Journal of Pathology, 页码:1525-1541 , 文章类型: Article,,卷期:2010年176-3]
- Angiogenesis and lymphangiogenesis participate in many inflammatory diseases, and their reversal is thought to be beneficial. However, the extent of reversibility of vessel remodeling is poorly understood. We exploited t...
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