- Golgi protein FAPP2 tubulates membranes
[作者:Cao, XW; Coskun, U; Rossle, M; Buschhorn, SB; Grzybek, M; Dafforn, TR; Lenoir, M; Overduin, M; Simons, K,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21121-21125 , 文章类型: Article,,卷期:2009年106-50]
- The Golgi-associated four-phosphate adaptor protein 2 (FAPP2) has been shown to possess transfer activity for glucosylceramide both in vitro and in cells. We have previously shown that FAPP2 is involved in apical transpo...
- Genetic dissection of floridean starch synthesis in the cytosol of the model dinoflagellate Crypthecodinium cohnii
[作者:Dauvillee, D; Deschamps, P; Ral, JP; Plancke, C; Putaux, JL; Devassine, J; Durand-Terrasson, A; Devin, A; Ball, SG,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21126-21130 , 文章类型: Article,,卷期:2009年106-50]
- Starch defines an insoluble semicrystalline form of storage polysaccharides restricted to Archaeplastida (red and green algae, land plants, and glaucophytes) and some secondary endosymbiosis derivatives of the latter. Wh...
- Dysbindin regulates hippocampal LTP by controlling NMDA receptor surface expression
[作者:Tang, TTT; Yang, F; Chen, BS; Lu, Y; Ji, YY; Roche, KW; Lu, B,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21395-21400 , 文章类型: Article,,卷期:2009年106-50]
- Abnormalities in NMDA receptor (NMDAR) function have been implicated in schizophrenia. Here, we show that dysbindin, a schizophrenia-susceptibility gene widely expressed in the forebrain, controls the surface expression ...
- The transcriptional coactivator PGC-1 alpha mediates exercise-induced angiogenesis in skeletal muscle
[作者:Chinsomboon, J; Ruas, J; Gupta, RK; Thom, R; Shoag, J; Rowe, GC; Sawada, N; Raghuram, S; Arany, Z,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21401-21406 , 文章类型: Article,,卷期:2009年106-50]
- Peripheral arterial disease (PAD) affects 5 million people in the US and is the primary cause of limb amputations. Exercise remains the single best intervention for PAD, in part thought to be mediated by increases in cap...
- A circadian clock in macrophages controls inflammatory immune responses
[作者:Keller, M; Mazuch, J; Abraham, U; Eom, GD; Herzog, ED; Volk, HD; Kramer, A; Maier, B,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21407-21412 , 文章类型: Article,,卷期:2009年106-50]
- Time of day-dependent variations of immune system parameters are ubiquitous phenomena in immunology. The circadian clock has been attributed with coordinating these variations on multiple levels; however, their molecular...
- A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase
[作者:Jarosz, DF; Cohen, SE; Delaney, JC; Essigmann, JM; Walker, GC,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21137-21142 , 文章类型: Article,,卷期:2009年106-50]
- The only Y-family DNA polymerase conserved among all domains of life, DinB and its mammalian ortholog pol kappa, catalyzes proficient bypass of damaged DNA in translesion synthesis (TLS). Y-family DNA polymerases, includ...
- Studies on expression and function of the TMEM16A calcium-activated chloride channel
[作者:Huang, F; Rock, JR; Harfe, BD; Cheng, T; Huang, XZ; Jan, YN; Jan, LY,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21413-21418 , 文章类型: Article,,卷期:2009年106-50]
- Calcium-activated chloride channels (CaCC) with similar hallmark features are present in many cell types and mediate important physiological functions including epithelial secretion, sensory signal transduction, and smoo...
- A protein kinase-phosphatase pair interacts with an ion channel to regulate ABA signaling in plant guard cells
[作者:Lee, SC; Lan, WZ; Buchanan, BB; Luan, S,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21419-21424 , 文章类型: Article,,卷期:2009年106-50]
- The plant hormone abscisic acid (ABA) serves as a physiological monitor to assess the water status of plants and, under drought conditions, induces stomatal pore closure by activating specific ion channels, such as a slo...
- Activity of guard cell anion channel SLAC1 is controlled by drought-stress signaling kinase-phosphatase pair
[作者:Geiger, D; Scherzer, S; Mumm, P; Stange, A; Marten, I; Bauer, H; Ache, P; Matschi, S; Liese, A; Al-Rasheid, KAS; Romeis, T; Hedrich, R,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21425-21430 , 文章类型: Article,,卷期:2009年106-50]
- In response to drought stress the phytohormone ABA (abscisic acid) induces stomatal closure and, therein, activates guard cell anion channels in a calcium-dependent as well as-independent manner. Two key components of th...
- A minimal sequence code for switching protein structure and function
[作者:Alexander, PA; He, YA; Chen, YH; Orban, J; Bryan, PN,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21149-21154 , 文章类型: Article,,卷期:2009年106-50]
- We present here a structural and mechanistic description of how a protein changes its fold and function, mutation by mutation. Our approach was to create 2 proteins that (i) are stably folded into 2 different folds, (ii)...
- Acidianus filamentous virus 1 coat proteins display a helical fold spanning the filamentous archaeal viruses lineage
[作者:Goulet, A; Blangy, S; Redder, P; Prangishvili, D; Felisberto-Rodrigues, C; Forterre, P; Campanacci, V; Cambillau, C,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21155-21160 , 文章类型: Article,,卷期:2009年106-50]
- Acidianus filamentous virus 1 (AFV1), a member of the Lipothrixviridae family, infects the hyperthermophilic, acidophilic crenarchaeaon Acidianus hospitalis. The virion, covered with a lipidic outer shell, is 9,100-angst...
- Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans
[作者:Rodrigues, SM; Saslow, LR; Garcia, N; John, OP; Keltner, D,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21437-21441 , 文章类型: Article,,卷期:2009年106-50]
- Oxytocin, a peptide that functions as both a hormone and neurotransmitter, has broad influences on social and emotional processing throughout the body and the brain. In this study, we tested how a polymorphism (rs53576) ...
- The time course of word retrieval revealed by event-related brain potentials during overt speech
[作者:Costa, A; Strijkers, K; Martin, C; Thierry, G,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:21442-21446 , 文章类型: Article,,卷期:2009年106-50]
- Speech production is one of the most fundamental activities of humans. A core cognitive operation involved in this skill is the retrieval of words from long-term memory, that is, from the mental lexicon. In this article,...
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