- Apurinic/Apyrimidinic Endonuclease (APE1) Gene Polymorphisms and Lung Cancer Risk in Relation To Tobacco Smoking
[作者:Agachan, B; Kucukhuseyin, O; Aksoy, P; Turna, A; Yaylim, I; Gormus, U; Ergen, A; Zeybek, U; Dalan, B; Isbir, T,期刊:Anticancer Research, 页码:2417-2420 , 文章类型: Article,,卷期:2009年29-6]
- Background: Polymorphisms altering DNA repair capacity may lead to synergistic effects with tobacco carcinogen-induced lung cancer risk. Based on this hypothesis, the relationship between APEI polymorphism, smoking and t...
- Proton Transport Inhibitors as Potentially Selective Anticancer Drugs
[作者:Harguindey, S; Arranz, JL; Wahl, ML; Orive, G; Reshkin, SJ,期刊:Anticancer Research, 页码:2127-2136 , 文章类型: Review,,卷期:2009年29-6]
- Different research groups have recently described a proton [H+]-related mechanism underlying the initiation and progression of the neoplastic process in which all cancer cells and tissues, regardless of their origin and ...
- Demethylation of the CD133 Gene Is Frequently Detected in Advanced Colorectal Cancer
[作者:Hibi, K; Sakata, M; Kitamura, YH; Sakuraba, K; Shirahata, A; Goto, T; Mizukami, H; Saito, M; Ishibashi, K; Kigawa, G; Nemoto, H; Sanada, Y,期刊:Anticancer Research, 页码:2235-2237 , 文章类型: Article,,卷期:2009年29-6]
- Background: Recently, it has been reported that colorectal carcinoma is created and propagated by a small number of undifferentiated tumorigenic CD133(+) cells. Furthermore, it has been reported that CD133 expression is ...
- Significant Association of Ku80 Single Nucleotide Polymorphisms with Colorectal Cancer Susceptibility in Central Taiwan
[作者:Yang, MD; Hsu, YM; Kuo, YS; Chen, HS; Chang, CL; Wu, CN; Chang, CH; Liao, YM; Wang, HC; Wang, MF; Bau, DT,期刊:Anticancer Research, 页码:2239-2242 , 文章类型: Article,,卷期:2009年29-6]
- Aim: To evaluate the association between the polymorphisms of the Ku80 gene and the risk of colorectal cancer in Central Taiwan. Materials and Methods: In this hospital-based case-control study, the association of WO G-1...
- Selective Activity Against Proliferating Tumor Endothelial Cells by CVX-22, A Thrombospondin-1 Mimetic CovX-Body (TM)
[作者:Coronella, J; Li, LN; Johnson, K; Pirie-Shepherd, S; Roxas, G; Levin, N,期刊:Anticancer Research, 页码:2243-2252 , 文章类型: Article,,卷期:2009年29-6]
- CVX-22 is a CovX-Body(TM), produced by covalently attaching a thrombospondin-1 (TSP-1) type I repeat peptide mimetic to a humanized IgG1 molecule. To dissect the antiangiogenic mechanism of CVX-22, the numbers and prolif...
- Estimation of Relationship Between the Structure of 1,2,3,4-Tetrahydroisoquinoline Derivatives Determined by a Semiempirical Molecular-Orbital Method and their Cytotoxicity
[作者:Ishihara, M; Hatano, H; Kawase, M; Sakagami, H,期刊:Anticancer Research, 页码:2265-2271 , 文章类型: Article,,卷期:2009年29-6]
- A semiempirical molecular-orbital method (CAChe 4.9, PM5) was applied to delineate the relationship between the cytotoxicity (evaluated by 50% cytotoxic concentration, CC50) of nineteen 1,2,3,4-tetrahydroisoquinoline der...
- Epigenetic Modifiers Exacerbate Oxidative Stress in Renal Proximal Tubule Cells
[作者:Nadasi, E; Clark, JS; Szanyi, I; Varjas, T; Ember, I; Baliga, P; Arany, I,期刊:Anticancer Research, 页码:2295-2299 , 文章类型: Article,,卷期:2009年29-6]
- Background: Increased production of reactive oxygen species (ROS) by anticancer drugs has been described in patients with various malignancies, which might attribute to their nephrotoxicity. Materials and Methods: The ef...
- Black Tea Polyphenols Target Matrix Metalloproteinases, RECK, Proangiogenic Molecules and Histone Deacetylase in a Rat Hepatocarcinogenesis Model
[作者:Murugan, RS; Vinothini, G; Hara, Y; Nagini, S,期刊:Anticancer Research, 页码:2301-2305 , 文章类型: Article,,卷期:2009年29-6]
- Background: The aim of this study was to evaluate the chemopreventive effects of black tea polyphenols (Polyphenon-B) on markers of invasion and angiogenesis during dimethylaminoazobenzene (DAB)-induced hepatocarcinogene...
- The Pathogenetic Mechanism of Anthracycline-induced Palmar-plantar Erythrodysesthesia
[作者:Martschick, A; Sehouli, J; Patzelt, A; Richter, H; Jacobi, U; Oskay-Ozcelik, G; Sterry, W; Lademann, J,期刊:Anticancer Research, 页码:2307-2313 , 文章类型: Article,,卷期:2009年29-6]
- Background: Anthracyclines, such as pegylated liposomal doxorubicin (PLD) and epirubicin (EP), are effective for the treatment of malignant tumors. Unfortunately, their implementation in therapy is limited due to severe ...
- Combination Effect between Bortezomib and Tumor Necrosis Factor alpha on Gefitinib-resistant Non-small Cell Lung Cancer Cell Lines
[作者:Kusumoto, S; Sugiyama, T; Ando, K; Hosaka, T; Ishida, H; Shirai, T; Yamaoka, T; Okuda, K; Hirose, T; Ohnishi, T; Inoue, F; Kanome, T; Kadofuku, T; Saijo, N; Adachii, M; Ohmori, T,期刊:Anticancer Research, 页码:2315-2322 , 文章类型: Article,,卷期:2009年29-6]
- Tumor cells that have acquired resistance to gefitinib may complicate the future treatment of patients with non-small cell lung cancer (NSCLC). To investigate the mechanisms of acquired resistance, an acquired gefitinib-...
- A Role for the Substance P/NK-1 Receptor Complex in Cell Proliferation in Oral Squamous Cell Carcinoma
[作者:Brener, S; Gonzalez-Moles, MA; Tostes, D; Esteban, F; Gil-Montoya, JA; Ruiz-Avila, I; Bravo, M; Munoz, M,期刊:Anticancer Research, 页码:2323-2329 , 文章类型: Article,,卷期:2009年29-6]
- Objective: To investigate the presence and distribution of substance P (SP) and neurokinin I receptor (NK-IR) in oral squamous cell carcinoma (OSCC) and their relationship with proliferation. Patients and Methods: Ninety...
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