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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共63条记录   Structure-activity relationship of okadaic acid, a potent protein phosphatases PP1 and PP2A inhibitor: 24-epi-okadaic acid and a 18-membered lactone analog. [作者：Kita, Masaki;Kuramoto, Makoto;Chiba, Tatsuhiko;Yamada, Akihiro;Yamada, Nobuko;Ishida, Takako;Haino, Takeharu;Yamada, Kaoru;Ijuin, Yasuharu;Ohno, Osamu;Uemura, Daisuke;,期刊：Heterocycles, 页码：1033-1042 , 文章类型： 研究论文，,卷期：2008年76-2] X-ray crystallog. anal. and structure-activity relationship of okadaic acid revealed that the flexible cavity structure stabilized by intramol. hydrogen bonds is important for its potent cytotoxicity. Electrooxidative desulfurization/chlorination. A facile synthesis of 4-chloro-2-azetidinones, a potent intermediate for carbapenems. [作者：Kuroboshi, Manabu;Miyada, Masayoshi;Tateyama, Syoichi;Tanaka, Hideo;,期刊：Heterocycles, 页码：1471-1484 , 文章类型： 研究论文，,卷期：2008年76-2] (3S,4R)-3-[1'(R)-tert-Butyldimethylsiloxyethyl]-4-chloro-2-azetidinone, a potent intermediate for the synthesis of carbapenem antibiotics, was synthesized by thermal ring opening/acylation of (3S,5R,6S)-6-[1'(R)-tert-but... Synthesis of oriented anti-virus 7-O-substituted apigenins. [作者：Oyama, Kin-ichi;Kondo, Tadao;Yoshida, Kumi;,期刊：Heterocycles, 页码：1607-1615 , 文章类型： 研究论文，,卷期：2008年76-2] 7-O-Substituted apigenins were synthesized for searching antiviral compds. Using a com. available naringenin as a starting material, 7-O-methylapigenin and 7 unnatural 7-O-substituted apigenin derivs. were prepd. via 4'... Synthesis of 14,15-epoxyisoprostane A2 phosphorylcholine. [作者：Acharya, Hukum P.;Miyoshi, Kei;Takashima, Yuji;Ogawa, Narihito;Kobayashi, Yuichi;,期刊：Heterocycles, 页码：1181-1189 , 文章类型： 研究论文，,卷期：2008年76-2] The product of the Cu-promoted allylic substitution of the 4-hydroxycyclopent-2-enyl ester with Me3SiCYCCH2MgBr was converted to the cyclopentenone with the PMBO(CH2)4CH:CHCH2 side chain (PMB = 4-MeOC6H4CH2). Aldol reac... 2,6-Dimethyl-4-nitrobenzoic anhydride (DMNBA): an effective coupling reagent for the synthesis of carboxylic esters and lactones. [作者：Shiina, Isamu;Miyao, Ryo;,期刊：Heterocycles, 页码：1313-1328 , 文章类型： 研究论文，,卷期：2008年76-2] Various carboxylic esters are obtained at room temp. in excellent yields with high chemoselectivities from nearly equimolar amts. of carboxylic acids and alcs. using DMNBA with Et3N by the promotion of 4-(dimethylamino)p... Kinetic resolution of 1,2-diols using nitrogen-tethered bisimidazoline-copper(I) catalyzed benzoylation. [作者：Arai, Takayoshi;Mizukami, Tomoe;Mishiro, Asami;Yanagisawa, Akira;,期刊：Heterocycles, 页码：995-1000 , 文章类型： 研究论文，,卷期：2008年76-2] A nitrogen-tethered bisimidazoline (Nb-imidazoline) ligand was utilized in the Cu(I)-catalyzed benzoylation of 1,2-diols. With the assistance of (Me2CH)2NEt, the reaction of rac-1,2-diols with 2-MeC6H4COCl was smoothly ... Catalytic asymmetric synthesis of (-)-ritodrine hydrochloride via silyl enol ether amination using dirhodium(II) tetrakis[tetrafluorophthaloyl-(S)-tert-leucinate]. [作者：Tanaka, Masahiko;Nakamura, Seiichi;Anada, Masahiro;Hashimoto, Shunichi;,期刊：Heterocycles, 页码：1633-1645 , 文章类型： 研究论文，,卷期：2008年76-2] A catalytic asym. synthesis of (-)-ritodrine.HCl was achieved, incorporating an enantioselective amination of a (Z)-silyl enol ether derived from 4-benzoxypropiophenone with [(2-nitrophenylsulfonyl)imino]phenyliodinane (... Regioselective Mannich reaction of phenols under high pressure using dichloromethane as C1 unit. [作者：Matsumoto, Kiyoshi;Joho, Kouta;Mimori, Seisuke;Iida, Hirokazu;Hamana, Hiroshi;Kakehi, Akikazu;,期刊：Heterocycles, 页码：1061-1067 , 文章类型： 研究论文，,卷期：2008年76-2] The regioselectivity in Mannich reaction of 4-, 3-, and 2-substituted phenols with typical heterocyclic amines was investigated under newly developed reaction conditions. PhOH and 4-alkyl- and 4-chlorophenols predominan... Deprotonative zincation of heteroaromatics using ZnI2 and tert-Bu-P4 base. [作者：Imahori, Tatsushi;Suzawa, Koichi;Kondo, Yoshinori;,期刊：Heterocycles, 页码：1057-1060 , 文章类型： 研究论文，,卷期：2008年76-2] The direct deprotonative zincation of diazines was accomplished using the combination of ZnI2 and t-Bu-P4 base and unique regioselectivities of zincation were obsd. The diazinylzinc compds. reacted with aryl halides in ... The NCN-type pincer complex of palladium(II) with a 2,6-bis(2-pyridyl)-4-tert-butylbenzene tridentate ligand: synthesis, structure and catalytic activity in the Mizoroki-Heck reaction. [作者：Hirano, Yuichi;Saiki, Yuji;Taji, Hideki;Matsukawa, Shiro;Yamamoto, Yohsuke;,期刊：Heterocycles, 页码：1585-1592 , 文章类型： 研究论文，,卷期：2008年76-2] The reaction of 1-bromo-4-tert-butyl-2,6-diiodobenzene with 2-pyridylzinc chloride in the presence of catalytic Pd(PPh3)4 afforded an NCN-type pincer Pd(II) complex with 2 pyridine donors. The structure of the complex w... A new chiral synthesis of a bicyclic enedione containing a seven-membered ring mediated by a combination of chiral amine and Bronsted acid. [作者：Nagamine, Takashi;Inomata, Kohei;Endo, Yasuyuki;,期刊：Heterocycles, 页码：1191-1204 , 文章类型： 研究论文，,卷期：2008年76-2] Several chiral amines bearing a heterocyclic moiety, such as pyrrolidine, piperazine, or tetrazole, were prepd. from L-phenylalanine. The enantioselectivity of the intramol. asym. aldol reaction mediated by a combination... Synthesis of 1,2-azulenequinone derivatives by bromine oxidation. [作者：Wakabayashi, Hidetsugu;Irinamihira, Osamu;Shibata, Satoshi;Kurihara, Teruo;Uchiyama, Yuzuru;Ohta, Akira;Fujimori, Kunihide;,期刊：Heterocycles, 页码：1133-1140 , 文章类型： 研究论文，,卷期：2008年76-2] Treatment of 2-hydroxyazulene with 3 equiv pyridinium.HBr3 in aq. THF-AcOH at 0?for 1 h afforded 1,1,3-tribromoazulene-2-one (I). 3-Bromo-1,2-azulenequinone (II) was obtained by hydrolysis of I in the presence of Ag2O. ... Construction of chiral quaternary carbon centers via palladium-catalyzed asymmetric deconjugative allylation. [作者：Yamamoto, Hiroki;Oonishi, Yoshihiro;Sato, Yoshihiro;,期刊：Heterocycles, 页码：1485-1495 , 文章类型： 研究论文，,卷期：2008年76-2] A Pd(0)-catalyzed asym. deconjugative allylation of various Knoevenagel products and allylic compds. was investigated. Various compds., having a quaternary C center directly attached to sp2-C centers including a 1,3-die... Development of column-free alkoxycarbonyl, aryloxycarbonyl, and acyl transfer reagents. [作者：Shimizu, Mamoru;Sodeoka, Mikiko;,期刊：Heterocycles, 页码：1301-1312 , 文章类型： 研究论文，,卷期：2008年76-2] Easy-to-handle alkoxycarbonyl, aryloxycarbonyl, and acyl transfer reagents, which contain 3-nitro-1,2,4-triazole (NT) as a leaving group, were developed. With these reagents (NT reagents), which are stable nonhygroscopi... DTBS effect: the unique sterically driven director for a-galactosylation. [作者：Imamura, Akihiro;Ando, Hiromune;Ishida, Hideharu;Kiso, Makoto;,期刊：Heterocycles, 页码：883-908 , 文章类型： 综述，,卷期：2008年76-2] A review with refs. on the chem. of 1,2-cis glycosylations and the state-of-the-art methods, highlighting the DTBS (di-tert-butylsilylene)-directed a-galactosylation that was recently developed by our group. The key fea...