- Effect of Institution-Wide Policy of Colonoscopy Withdrawal Time >= 7 Minutes on Polyp Detection
[作者:Sawhney, MS; Cury, MS; Neeman, N; Ngo, LH; Lewis, JM; Chuttani, R; Pleskow, DK; Aronson, MD,期刊:Gastroenterology, 页码:1892-1898 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Practice guidelines recommend that endoscopists spend at least 7 minutes examining the colonic mucosa during colonoscopy withdrawal to optimize polyp yield. The aim of this study was to determine if th...
- Helicobacter pylori Lipopolysaccharide Interacts With TFF1 in a pH-Dependent Manner
[作者:Reeves, EP; Ali, T; Leonard, P; Hearty, S; O'Kennedy, R; May, FEB; Westley, BR; Josenhans, C; Rust, M; Suerbaum, S; Smith, A; Drumm, B; Clyne, M,期刊:Gastroenterology, 页码:2043-2054 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Little is known about how bacteria establish chronic infections of mucosal surfaces. Helicobacter pylori (H pylori), a chronic pathogen that lives in the gastric mucosa of humans, interacts with the tr...
- Bleeding and Perforation After Outpatient Colonoscopy and Their Risk Factors in Usual Clinical Practice
[作者:Rabeneck, L; Paszat, LF; Hilsden, RJ; Saskin, R; Leddin, D; Grunfeld, E; Wai, E; Goldwasser, M; Sutradhar, R; Stukeli, TA,期刊:Gastroenterology, 页码:1899-1906 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: The most widely quoted complication rates for colonoscopy are from case series performed by expert endoscopists. Our objectives were to evaluate the rates of bleeding, perforation, and death associated...
- Heme Oxygenase-1 Protects Interstitial Cells of Cajal From Oxidative Stress and Reverses Diabetic Gastroparesis
[作者:Choi, KM; Gibbons, SJ; Nguyen, TV; Stoltz, GJ; Lurken, MS; Ordog, T; Szurszewski, JH; Farrugia, G,期刊:Gastroenterology, 页码:2055-2064 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Diabetic gastroparesis (delayed gastric emptying) is a well-recognized complication of diabetes that causes considerable morbidity and makes glucose control difficult. Interstitial cells of Cajal, whic...
- Direct Health Care Costs of Crohn's Disease and Ulcerative Colitis in US Children and Adults
[作者:Kappelman, MD; Rifas-Shiman, SL; Porter, CQ; Ollendorf, DA; Sandler, RS; Galanko, JA; Finkelstein, JA,期刊:Gastroenterology, 页码:1907-1913 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Data regarding the health care costs of inflammatory bowel disease (IBD) in the United States are limited. The objectives of this study were to estimate the direct costs of Crohn's disease (CD) and ulc...
- Effects of Attention on Visceral Stimulus Intensity Encoding in the Male Human Brain
[作者:Coen, SJ; Aziz, Q; Yaguez, L; Brammer, M; Williams, SCR; Gregory, LJ,期刊:Gastroenterology, 页码:2065-2074 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Hypervigilance is considered important in pain perception in functional gastrointestinal disorders. Nonetheless, a comprehensive assessment of the influence of attention on brain processing of visceral...
- A Rat Model of Chronic Postinflammatory Visceral Pain Induced by Deoxycholic Acid
[作者:Traub, RJ; Tang, B; Ji, YP; Pandya, S; Yfantis, H; Sun, Y,期刊:Gastroenterology, 页码:2075-2083 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Chronic visceral hyperalgesia is considered an important pathophysiologic symptom in irritable bowel syndrome (IBS); previous gastrointestinal inflammation is a potent etiologic factor for developing I...
- Thiazolidinedione Therapy Is Not Associated With Increased Colonic Neoplasia Risk in Patients With Diabetes Mellitus
[作者:Lewis, JD; Capra, AM; Achacoso, NS; Ferrara, A; Levin, TR; Quesenberry, CP; Habeli, LA,期刊:Gastroenterology, 页码:1914-1923 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Thiazolidinedione ligands for peroxisome proliferator-activated receptor gamma(PPAR gamma), are used to treat diabetes. PPAR gamma is highly expressed in the colon, and exposure to thiazolidinediones h...
- Development of Nonalcoholic Steatohepatitis in Insulin-Resistant Liver-Specific S503A Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Mutant Mice
[作者:Lee, SJ; Heinrich, G; Fedorova, L; Al-Share, QY; Ledford, KJ; Fernstrom, MA; McInerney, MF; Erickson, SK; Gatto-Weis, C; Najjar, SM,期刊:Gastroenterology, 页码:2084-2095 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Liver-specific inactivation of carcinoembryonic antigen-related cell adhesion molecule 1 causes hyperinsulinemia and insulin resistance, which result from impaired insulin clearance, in liver-specific ...
- Glucagon Receptor Signaling Is Essential for Control of Murine Hepatocyte Survival
[作者:Sinclair, EM; Yusta, B; Streutker, C; Baggio, LL; Koehler, J; Charron, MJ; Drucker, DJ,期刊:Gastroenterology, 页码:2096-2106 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Glucagon action in the liver is essential for control of glucose homeostasis and the counterregulatory response to hypoglycemia. Because receptors for the related peptides glucagon-like peptide-1 and g...
- Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-induced Liver Injury in the United States
[作者:Chalasani, N; Fontana, RJ; Bonkovsky, HL; Watkins, PB; Davern, T; Serrano, J; Yang, HQ; Rochon, J,期刊:Gastroenterology, 页码:1924-1934 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Idiosyncratic drug-induced liver injury (DILI) is among the most common causes of acute liver failure in the United States, accounting for approximately 13% of cases. A prospective study was begun in 2...
- Identification of CD4 T-Cell Epitopes in Soluble Liver Antigen/Liver Pancreas Autoantigen in Autoimmune Hepatitis
[作者:Mix, H; Weiler-Normann, C; Thimme, R; Ahlenstiel, G; Shin, EC; Herkel, J; David, CS; Lohse, AW; Rehermann, B,期刊:Gastroenterology, 页码:2107-2118 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease associated with autoantibodies and liver-infiltrating lymphocytes. Although autoantibodies are tested routinely to diagnose and classi...
- Aminotransferase Levels and 20-Year Risk of Metabolic Syndrome, Diabetes, and Cardiovascular Disease
[作者:Goessling, W; Massaro, JM; Vasan, RS; D'Agostino, RB; Ellison, RC; Fox, CS,期刊:Gastroenterology, 页码:1935-1944 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of obesity and metabolic syndrome (MetS). Alanine aminotransferase (ALT) levels are used to detect NAFLD and have also been associa...
- Epigenetic Changes Induced by Reactive Oxygen Species in Hepatocellular Carcinoma: Methylation of the E-cadherin Promoter
[作者:Lim, SO; Gu, JM; Kim, MS; Kim, HS; Park, YN; Park, CK; Cho, JW; Park, YM; Jung, G,期刊:Gastroenterology, 页码:2128-2140 , 文章类型: Article,,卷期:2008年135-6]
- Background & Aims: In addition to genetic alterations, epigenetic changes underlie tumor progression and metastasis. Promoter methylation can silence tumor suppressor genes, and reactive oxygen species (ROS) promote DNA ...
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