- Estrogen Receptor Genotypes Influence Hot Flash Prevalence and Composite Score Before and After Tamoxifen Therapy
[作者:Jin, Y; Hayes, DF; Li, L; Robarge, JD; Skaar, TC; Philips, S; Nguyen, A; Schott, A; Hayden, J; Lemler, S; Storniolo, AM; Flockhart, DA; Stearns, V,期刊:Journal of clinical oncology, 页码:5849-5854 , 文章类型: Article,,卷期:2008年26-36]
- PurposeHot flashes are common and frequently lead to drug discontinuation among women prescribed tamoxifen. We determined whether genetic polymorphisms in estrogen receptors ( ESRs) alpha and beta ( ESR1 and ESR2, respec...
- Managing Symptoms Among Patients With Breast Cancer During Chemotherapy: Results of a Two-Arm Behavioral Trial
[作者:Given, CW; Sikorskii, A; Tamkus, D; Given, B; You, M; McCorkle, R; Champion, V; Decker, D,期刊:Journal of clinical oncology, 页码:5855-5862 , 文章类型: Article,,卷期:2008年26-36]
- PurposeIn this study, we compare symptom response and times to response among patients with breast cancer who were assigned to either a cognitive behavioral Nurse-Administered Symptom Management intervention or an Automa...
- Predictive Model for Survival in Patients With Advanced Cancer
[作者:Chow, E; Abdolell, M; Panzarella, T; Harris, K; Bezjak, A; Warde, P; Tannock, I,期刊:Journal of clinical oncology, 页码:5863-5869 , 文章类型: Article,,卷期:2008年26-36]
- PurposeTo derive and validate a simple predictive model for survival of patients with metastatic cancer attending a palliative radiotherapy clinic.Patients and MethodsWe described previously a model predicting survival o...
- Unresolved Grief in a National Sample of Bereaved Parents: Impaired Mental and Physical Health 4 to 9 Years Later
[作者:Lannen, PK; Wolfe, J; Prigerson, HG; Onelov, E; Kreicbergs, UC,期刊:Journal of clinical oncology, 页码:5870-5876 , 文章类型: Article,,卷期:2008年26-36]
- PurposeTo assess unresolved parental grief, the associated long-term impact on mental and physical health, and health service use.Patients and MethodsThis anonymous, mail-in questionnaire study was performed as a populat...
- Multinational Study of Cancer Patients and Their Children: Factors Associated With Family Functioning
[作者:Schmitt, F; Piha, J; Helenius, H; Baldus, C; Kienbacher, C; Steck, B; Thastum, M; Watson, M; Romer, G,期刊:Journal of clinical oncology, 页码:5877-5883 , 文章类型: Article,,卷期:2008年26-36]
- PurposeThis study examined factors associated with family functioning in cancer patients' families with dependent children.Patients and MethodsA sample of 381 families ( 639 parents and 489 children) was recruited simult...
- Impact of Caring for a Child With Cancer on Parents' Health-Related Quality of Life
[作者:Klassen, AF; Klaassen, R; Dix, D; Pritchard, S; Yanofsky, R; O'Donnell, M; Scott, A; Sung, L,期刊:Journal of clinical oncology, 页码:5884-5889 , 文章类型: Article,,卷期:2008年26-36]
- PurposeTo compare the health-related quality of life ( QOL) of parents of children who are undergoing treatment for cancer with that of Canadian population norms and to identify important parent and child predictors of p...
- Depression in Family Caregivers of Cancer Patients: The Feeling of Burden As a Predictor of Depression
[作者:Rhee, YS; Yun, YH; Park, S; Shin, DO; Lee, KM; Yoo, HJ; Kim, JH; Kim, SO; Lee, R; Lee, YO; Kim, NS,期刊:Journal of clinical oncology, 页码:5890-5895 , 文章类型: Article,,卷期:2008年26-36]
- PurposeThe purpose of this study was to explore the prevalence of and to identify the predictors of depression in family caregivers of cancer patients.Patients and MethodsWe enrolled 310 caregivers of cancer patients fro...
- Relationship of Treatment-Related Cytopenias and Response to Lenalidomide in Patients With Lower-Risk Myelodysplastic Syndromes
[作者:Sekeres, MA; Maciejewski, JP; Giagounidis, AAN; Wride, K; Knight, R; Raza, A; List, AF,期刊:Journal of clinical oncology, 页码:5943-5949 , 文章类型: Article,,卷期:2008年26-36]
- PurposePatients with myelodysplastic syndromes ( MDS) often require treatment with growth factors ( GFs) or non-GF therapies. One non-GF drug, lenalidomide, is particularly effective at achieving transfusion independence...
- Phase I/II Study of Ipilimumab for Patients With Metastatic Melanoma
[作者:Weber, JS; O'Day, S; Urba, W; Powderly, J; Nichol, G; Yellin, M; Snively, J; Hersh, E,期刊:Journal of clinical oncology, 页码:5950-5956 , 文章类型: Article,,卷期:2008年26-36]
- PurposeThe primary objective of this phase I/II study was to determine the safety and pharmacokinetic profile of either transfectoma- or a hybridoma-derived ipilimumab. Secondary objectives included determination of a ma...
- Polymorphism in the Microglial Cell-Mobilizing CX3CR1 Gene Is Associated With Survival in Patients With Glioblastoma
[作者:Rodero, M; Marie, Y; Coudert, M; Blondet, E; Mokhtari, K; Rousseau, A; Raoul, W; Carpentier, C; Sennlaub, F; Deterre, P; Delattre, JY; Debre, P; Sanson, M; Combadiere, C,期刊:Journal of clinical oncology, 页码:5957-5964 , 文章类型: Article,,卷期:2008年26-36]
- PurposeFew reliable prognostic molecular markers have been characterized for glioblastoma multiforme ( GBM), considered the deadliest of human cancers. We hypothesized that genetic polymorphisms in chemokines and their r...
- Carcinoma of the Lower Uterine Segment: A Newly Described Association With Lynch Syndrome
[作者:Westin, SN; Lacour, RA; Urbauer, DL; Luthra, R; Bodurka, DC; Lu, KH; Broaddus, RR,期刊:Journal of clinical oncology, 页码:5965-5971 , 文章类型: Article,,卷期:2008年26-36]
- PurposeEndometrial carcinoma in the lower uterine segment ( LUS) is a poorly described cancer that can be clinically confused with endocervical carcinoma. We performed a case-comparison study to document the clinicopatho...
- Effect of BRCA1 Haplotype on Survival of Non-Small-Cell Lung Cancer Patients Treated With Platinum-Based Chemotherapy
[作者:Kim, HT; Lee, JE; Shin, ES; Yoo, YK; Cho, JH; Yun, MH; Kim, YH; Kim, SK; Kim, HJ; Jang, TW; Kwak, SM; Kim, CS; Ryu, JS,期刊:Journal of clinical oncology, 页码:5972-5979 , 文章类型: Article,,卷期:2008年26-36]
- PurposeTo determine whether germ-line variations in BRCA1 affect outcome in non-small-cell lung cancer ( NSCLC) patients treated with platinum combination chemotherapy.Patients and MethodsWe evaluated the associations of...
- Risk-Adapted Salvage Treatment With Single or Tandem Autologous Stem-Cell Transplantation for First Relapse/Refractory Hodgkin's Lymphoma: Results of the Prospective Multicenter H96 Trial by the GELA/SFGM Study Group
[作者:Morschhauser, F; Brice, P; Ferme, C; Divine, M; Salles, G; Bouabdallah, R; Sebban, C; Voillat, L; Casasnovas, O; Stamatoullas, A; Bouabdallah, K; Andre, M; Jais, JP; Cazals-Hatem, D; Gisselbrecht, C,期刊:Journal of clinical oncology, 页码:5980-5987 , 文章类型: Article,,卷期:2008年26-36]
- PurposeA prospective multicenter trial evaluated a risk-adapted salvage treatment with single or tandem autologous stem-cell transplantation ( ASCT) for 245 Hodgkin's lymphoma ( HL) patients who experience treatment fail...
- Self-Reported Practices and Attitudes of US Oncologists Regarding Off-Protocol Therapy
[作者:Peppercorn, J; Burstein, H; Miller, FG; Winer, E; Joffe, S,期刊:Journal of clinical oncology, 页码:5994-6000 , 文章类型: Article,,卷期:2008年26-36]
- Purpose Investigational cancer therapies being tested in clinical trials may be available outside of trials, or off-protocol (OPRx). We evaluated the practices and attitudes among US oncologists with regard to this contr...
- Surprised by Hope
[作者:Francis, PA,期刊:Journal of clinical oncology, 页码:6001-6002 , 文章类型: Article,,卷期:2008年26-36]
- Providing and maintaining hope for patients with incurable cancer is something that medical oncologists recognize as important. Yet the fine line that we frequently tread between giving a realistic prognosis to facilitat...
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