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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共70条记录   Identification and function of a cytoplasmic K+ site of the Na+,K+-ATPase [作者：Schack, VR; Morth, JP; Toustrup-Jensen, MS; Anthonisen, AN; Nissen, P; Andersen, JP; Vilsen, B,期刊：Journal of Biological Chemistry, 页码：27982-27990 , 文章类型： Article，,卷期：2008年283-41] A cytoplasmic nontransport K+/Rb+ site in the P-domain of the Na+, K+ -ATPase has been identified by anomalous difference Fourier map analysis of crystals of the [Rb-2] center dot E-2 center dot MgF42-form of the enzyme.... Protein tyrosine nitration of the flavin subunit is associated with oxidative modification of mitochondrial Complex II in the post-ischemic myocardium [作者：Chen, CL; Chen, JF; Rawale, S; Varadharaj, S; Kaumaya, PPT; Zweier, JL; Chen, YR,期刊：Journal of Biological Chemistry, 页码：27991-28003 , 文章类型： Article，,卷期：2008年283-41] Increased O-2(-) and NO production is a key mechanism of mitochondrial dysfunction in myocardial ischemia/reperfusion injury. A crucial segment of the mitochondrial electron transport chain is succinate ubiquinone reduct... Keratinocyte collagenase-1 expression requires an epidermal growth factor receptor autocrine mechanism (vol 274, pg 10372, 1999) [作者：Pilcher, BK; Dumin, J; Schwartz, MJ; Mast, BA; Schultz, GS; Parks, WC; Welgus, HG,期刊：Journal of Biological Chemistry, 页码：28004-28004 , 文章类型： Correction，,卷期：2008年283-41] Should I stay or should I go? Eukaryotic translation initiation factors 1 and 1A control start codon recognition [作者：Mitchell, SF; Lorsch, JR,期刊：Journal of Biological Chemistry, 页码：27345-27349 , 文章类型： Review，,卷期：2008年283-41] Start codon selection is a key step in translation initiation as it sets the reading frame for decoding. Two eukaryotic initiation factors, eIF1 and eIF1A, are key actors in this process. Recent work has elucidated many ... Life span extension and neuronal cell protection by Drosophila nicotinamidase [作者：Balan, V; Miller, GS; Kaplun, L; Balan, K; Chong, ZZ; Li, FQ; Kaplun, A; VanBerkum, MFA; Arking, R; Freeman, DC; Maiese, K; Tzivion, G,期刊：Journal of Biological Chemistry, 页码：27810-27819 , 文章类型： Article，,卷期：2008年283-41] The life span of model organisms can be modulated by environmental conditions that influence cellular metabolism, oxidation, or DNA integrity. The yeast nicotinamidase gene pnc1 was identified as a key transcriptional ta... Differential blocking effects of the acetaldehyde-derived DNA lesion N-2-ethyl-2 '-deoxyguanosine on transcription by multisubunit and single subunit RNA polymerases [作者：Cheng, TF; Hu, XP; Gnatt, A; Brooks, PJ,期刊：Journal of Biological Chemistry, 页码：27820-27828 , 文章类型： Article，,卷期：2008年283-41] Acetaldehyde, the first metabolite of ethanol, reacts with DNA to form adducts, including N-2-ethyl-2'-deoxyguanosine (N-2-Et-dG). Although the effects of N-2-Et-dG on DNA polymerases have been well studied, nothing is k... High sensitivity proteomics assisted discovery of a novel operon involved in the assembly of photosystem II, a membrane protein complex [作者：Wegener, KM; Welsh, EA; Thornton, LE; Keren, N; Jacobs, JM; Hixson, KK; Monroe, ME; Camp, DG; Smith, RD; Pakrasi, HB,期刊：Journal of Biological Chemistry, 页码：27829-27837 , 文章类型： Article，,卷期：2008年283-41] Photosystem II (PSII) is a large membrane protein complex that performs the water oxidation reactions of photosynthesis in cyanobacteria, algae, and plants. The unusual redox reactions in PSII often lead to damage, degra... Insight into the integrase-DNA recognition mechanism - A specific DNA-binding mode revealed by an enzymatically labeled integrase [作者：Delelis, O; Carayon, K; Guiot, E; Leh, H; Tauc, P; Brochon, JC; Mouscadet, JF; Deprez, E,期刊：Journal of Biological Chemistry, 页码：27838-27849 , 文章类型： Article，,卷期：2008年283-41] Integration catalyzed by integrase (IN) is a key process in the retrovirus life cycle. Many biochemical or structural human immunodeficiency virus, type 1 (HIV-1) IN studies have been severely impeded by its propensity t... The fourth extracellular loop of the alpha subunit of Na, K-ATPase [作者：Capendeguy, O; Iwaszkiewicz, J; Michielin, O; Horisberger, JD,期刊：Journal of Biological Chemistry, 页码：27850-27858 , 文章类型： Article，,卷期：2008年283-41] Na, K-ATPase is the main active transport system that maintains the large gradients of Na+ and K+ across the plasma membrane of animal cells. The crystal structure of a K+-occluding conformation of this protein has been ... Regulation of nuclear Ca2+ signaling by translocation of the Ca2+ messenger synthesizing enzyme ADP-ribosyl cyclase during neuronal depolarization [作者：Bezin, S; Charpentier, G; Lee, HC; Baux, G; Fossier, P; Cancela, JM,期刊：Journal of Biological Chemistry, 页码：27859-27870 , 文章类型： Article，,卷期：2008年283-41] In neurons, voltage-gated Ca2+ channels and nuclear Ca2+ signaling play important roles, such as in the regulation of gene expression. However, the link between electrical activity and biochemical cascade activation invo... Lysobisphosphatidic acid controls endosomal cholesterol levels [作者：Chevallier, J; Chamoun, Z; Jiang, GW; Prestwich, G; Sakai, N; Matile, S; Parton, RG; Gruenberg, J,期刊：Journal of Biological Chemistry, 页码：27871-27880 , 文章类型： Article，,卷期：2008年283-41] Most cell types acquire cholesterol by endocytosis of circulating low density lipoprotein, but little is known about the mechanisms of intra-endosomal cholesterol transport and about the primary cause of its aberrant acc... Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium Species [作者：Fulton, Z; McAlister, A; Wilce, MCJ; Brammananth, R; Zaker-Tabrizi, L; Perugini, MA; Bottomley, SP; Coppel, RL; Crellin, PK; Rossjohn, J; Beddoe, T,期刊：Journal of Biological Chemistry, 页码：27881-27890 , 文章类型： Article，,卷期：2008年283-41] Glycosyltransferases (GTs) are a large and ubiquitous family of enzymes that specifically transfer sugar moieties to a range of substrates. Mycobacterium tuberculosis contains a large number of GTs, many of which are ... The diaphanous-related formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing [作者：Hannemann, S; Madrid, R; Stastna, J; Kitzing, T; Gasteier, J; Schonichen, A; Bouchet, J; Jimenez, A; Geyer, M; Grosse, R; Benichou, S; Fackler, OT,期刊：Journal of Biological Chemistry, 页码：27891-27903 , 文章类型： Article，,卷期：2008年283-41] Diaphanous-related formins (DRFs) mediate GTPase-triggered actin rearrangements to regulate central cellular processes, such as cell motility and cytokinesis. The DRF FHOD1 interacts with the Rho-GTPase Rac1 and mediates... Changes of protein folding pathways by circular permutation - Overlapping nuclei promote global cooperativity [作者：Haglund, E; Lindberg, MO; Oliveberg, M,期刊：Journal of Biological Chemistry, 页码：27904-27915 , 文章类型： Article，,卷期：2008年283-41] The evolved properties of proteins are not limited to structure and stability but also include their propensity to undergo local conformational changes. The latter, dynamic property is related to structural cooperativity... Paclitaxel binding to human and murine MD-2 [作者：Zimmer, SM; Liu, J; Clayton, JL; Stephens, DS; Snyder, JP,期刊：Journal of Biological Chemistry, 页码：27916-27926 , 文章类型： Article，,卷期：2008年283-41] Paclitaxel (PTX) is an important cancer chemotherapeutic agent that binds to beta-tubulin and prevents mitosis through microtubule overstabilization. Recent evidence also implicates PTX in the induction of apoptosis of c... beta 1 integrin-mediated effects of tenascin-R domains EGFL and FN6-8 on neural stem/progenitor cell proliferation and differentiation in vitro [作者：Liao, H; Huang, WH; Schachner, M; Guan, Y; Guo, JJ; Yan, J; Qin, J; Bai, XS; Zhang, LY,期刊：Journal of Biological Chemistry, 页码：27927-27936 , 文章类型： Article，,卷期：2008年283-41] Neural stem/progenitor cells (NSCs) have the capacity for self-renewal and differentiation into major classes of central nervous system cell types, such as neurons, astrocytes, and oligodendrocytes. The determination of ...