- Metalloproteinase- and gamma-Secretase-mediated Cleavage of Protein-tyrosine Phosphatase Receptor Type Z
[作者:Chow, JPH; Fujikawa, A; Shimizu, H; Suzuki, R; Noda, M,期刊:Journal of Biological Chemistry, 页码:30879-30889 , 文章类型: Article,,卷期:2008年283-45]
- Protein-tyrosine phosphatase receptor type Z (Ptprz) is preferentially expressed in the brain as a major chondroitin sulfate proteoglycan. Three splicing variants, two receptor isoforms and one secretory isoform, are kno...
- MicroRNA-221/222 Negatively Regulates Estrogen Receptor alpha and Is Associated with Tamoxifen Resistance in Breast Cancer
[作者:Zhao, JJ; Lin, JH; Yang, H; Kong, W; He, LL; Ma, X; Coppola, D; Cheng, JQ,期刊:Journal of Biological Chemistry, 页码:31079-31086 , 文章类型: Article,,卷期:2008年283-45]
- A search for regulators of estrogen receptor alpha(ER alpha) expression has yielded a set of microRNAs (miRNAs) for which expression is specifically elevated in ER alpha-negative breast cancer. Here we show distinct expr...
- A Novel Small Molecule Regulator of Guanine Nucleotide Exchange Activity of the ADP-ribosylation Factor and Golgi Membrane Trafficking
[作者:Pan, HL; Yu, J; Zhang, LH; Carpenter, A; Zhu, H; Li, L; Ma, DW; Yuan, JY,期刊:Journal of Biological Chemistry, 页码:31087-31096 , 文章类型: Article,,卷期:2008年283-45]
- An image-based phenotypic screen was developed to identify small molecule regulators of intracellular traffic. Using this screen we found that AG1478, a previously known inhibitor of epidermal growth factor receptor, had...
- Tetrasulfated Disaccharide Unit in Heparan Sulfate ENZYMATIC FORMATION AND TISSUE DISTRIBUTION
[作者:Mochizuki, H; Yoshida, K; Shibata, Y; Kimata, K,期刊:Journal of Biological Chemistry, 页码:31237-31245 , 文章类型: Article,,卷期:2008年283-45]
- We previously reported that the heparan sulfate 3-O-sulfo-transferase (3OST)-5 produces a novel component of heparan sulfate, i.e. the tetrasulfated disaccharide (Di-tetraS) unit (Mochizuki, H., Yoshida, K., Gotoh, M., S...
- DUSP6 (MKP3) Null Mice Show Enhanced ERK1/2 Phosphorylation at Baseline and Increased Myocyte Proliferation in the Heart Affecting Disease Susceptibility
[作者:Maillet, M; Purcell, NH; Sargent, MA; York, AJ; Bueno, OF; Molkentin, JD,期刊:Journal of Biological Chemistry, 页码:31246-31255 , 文章类型: Article,,卷期:2008年283-45]
- The strength and duration of mitogen-activated protein kinase signaling is regulated through phosphorylation and dephosphorylation by dedicated dual-specificity kinases and phosphatases, respectively. Here we investigate...
- Heterogeneous nuclear ribonucleoprotein A1 regulates cyclin D1 and c-myc internal ribosome entry site function through Akt signaling. (vol 283, pg 23274, 2008)
[作者:Jo, OD; Martin, J; Bernath, A; Masri, J; Lichtenstein, A; Gera, J,期刊:Journal of Biological Chemistry, 页码:31268-31268 , 文章类型: Correction,,卷期:2008年283-45]
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- Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype. (vol 280, pg 22530, 2005)
[作者:Thiruchelvam, M; Prokopenko, O; Cory-Slechta, DA; Buckley, B; Mirochnitchenko, O,期刊:Journal of Biological Chemistry, 页码:31268-31268 , 文章类型: Correction,,卷期:2008年283-45]
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- Diverse Functional Consequences of Mutations in the Na+/K+-ATPase alpha(2)-Subunit Causing Familial Hemiplegic Migraine Type 2
[作者:Tavraz, NN; Friedrich, T; Durr, KL; Koenderink, JB; Bamberg, E; Freilinger, T; Dichgans, M,期刊:Journal of Biological Chemistry, 页码:31097-31106 , 文章类型: Article,,卷期:2008年283-45]
- Mutations in ATP1A2, the gene coding for the Na+/K+-ATPase alpha(2)-subunit, are associated with both familial hemiplegic migraine and sporadic cases of hemiplegic migraine. In this study, we examined the functional prop...
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