Cellulose-derived chiral pyrrolidines were synthesized in excellent yields, regioselectivities, and stereoselectivities via a 1,3-dipolar cycloaddition reaction between levoglucosenone and azomethine ylides. An unprecede...
Hemiprotonated dimers of cytosine derivatives, implicated in the formation of the i-motif of DNA, have been created in solution and the gas phase. The mechanism of dimerization has been analyzed by mass spectrometry and ...
Novel thieno-imidazole based polymer P showed both colorimetric and ratiometric detections of Hg2+ as well as fluorometric detection of Zn2+ via fluorescence turn-on response with augmented lifetime. Its model polymer M ...
Inclusion complexation of diaryl dichalcogenides with either cholic acid or chiral diols results in their helicity discrimination and an induction of optical activity that can be detected by solid-state CD measurements.
A synthesis of the Prelog-Djerassi lactone [(+)-1] has been accomplished in three isolations and 57% overall yield from the known vinyl ortho ester 2. A Rh(I)-catalyzed asymmetric hydroformylation/crotylation tandem sequ...
Drakaea livida (Orchidaceae) is pollinated by sexual deception of the wasp Zaspilothynnus nigripes (Thynnidae). It is shown that the orchid emits the same compound, 2-hydroxymethyl-3-(3-methylbutyl)-5-methylpyrazine, tha...
An efficient iridium-catalyzed intramolecular Friedel-Crafts-type allylic alkylation reaction of phenols was developed, affording tetrahydro-isoquinolines with moderate to excellent yields, enantioselectivity, and good r...
An asymmetric synthesis of two new diastereomeric gamma-amino acids is described. Both molecules contain a cyclohexyl ring to limit conformational flexibility about the C-alpha-C-beta bond; they differ in having cis vs t...
A copper-based catalyst system for the direct coupling of polyfluoroarenes with propargyl phosphates has been developed. The catalysis can provide a rapid and concise access to (polyfluoroaryl)allenes, which can be impor...
Unsymmetrical bisazides containing chelating and nonchelating azido groups undergo chemoselective three-component copper(I)-catalyzed azide-alkyne conjugation reactions with two different alkyne molecules. In conjunction...
C-60-styryl Bodipy dyads that show strong absorption of visible light (epsilon = 64 600 M-1 cm(-1) at 657 nm) and a long-lived triplet excited state (tau(T)=123.2 mu s) are prepared. The dyads were used as heavy-atom-fre...
For fluorescent imaging of mercury ions in living species, two-photon probes with dual optical windows are in high demand but remain unexplored. Several dithioacetals were evaluated, and a probe was found, which, upon re...
Relative reactivities and absolute rate constants of the reactions of haloarenes with i-PrMgCl center dot LiCl were investigated in THF at 0 degrees C. The rate of the halogen-magnesium exchange decreases in the series A...
Phosphite-copper(I) complexes efficiently catalyzed the double borylation of internal silylated alkynes to provide vicinal diboronates with excellent regio- and stereoselectivity. The copper-catalyzed reaction between bi...
Direct, one-pot, operationally simple, and highly enantioselective iso-Pictet-Spengler reactions are reported. The reactions involve the condensation of either (1H-indol-4-yl)methanamine or 2-(1H-Indol-1-yl)ethanamine wi...
Lycojaponicumins A-C (1-3), three trace alkaloids isolated from Lycopodium japonicum, represent a unique heterocyclic skeleton formed by the new linkage C4-C9. Notably, lycojaponicumins A and B (1 and 2) are the first ex...