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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共50条记录   Cytotoxic Alkaloids from Fusarium incarnatum Associated with the Mangrove Tree Aegiceras corniculatum [作者：Ding, L; Dahse, HM; Hertweck, C,期刊：Journal of natural products, 页码：617-621 , 文章类型： Article，,卷期：2012年75-4] Several unusual alkaloids, N-2-methylpropyl-2-methylbutenamide (1), 2-acetyl-1,2,3,4-tetrahydro-beta-carboline (2), fusarine (3), fusamine (4), and 3-(1-aminoethylidene)-6-methyl-2H-pyran-2,4(3H)-dione (5), were isolated... Bioactive Carbazole Alkaloids from Clausena wallichii Roots [作者：Maneerat, W; Ritthiwigrom, T; Cheenpracha, S; Promgool, T; Yossathera, K; Deachathai, S; Phakhodee, W; Laphookhieo, S,期刊：Journal of natural products, 页码：741-746 , 文章类型： Article，,卷期：2012年75-4] Four new carbazole alkaloids, clausenawallines C-F (1-4), along with 18 known compounds (5-22) were isolated from the roots of Clausena wallichii. Compounds 3, 9, and 22 exhibited significant antibacterial activity again... Plumbagin Induces Apoptosis in Her2-Overexpressing Breast Cancer Cells through the Mitochondrial-Mediated Pathway [作者：Kawiak, A; Zawacka-Pankau, J; Lojkowska, E,期刊：Journal of natural products, 页码：747-751 , 文章类型： Article，,卷期：2012年75-4] Breast cancer is the leading cause of death-related cancers in women. Approximately 30% of breast cancers overexpress the Her2 oncogene, which is associated with a poor prognosis and increased resistance to chemotherapy.... Flacourtosides A-F, Phenolic Glycosides Isolated from Flacourtia ramontchi [作者：Bourjot, M; Leyssen, P; Eydoux, C; Guillemot, JC; Canard, B; Rasoanaivo, P; Gueritte, F; Litaudon, M,期刊：Journal of natural products, 页码：752-758 , 文章类型： Article，,卷期：2012年75-4] In an effort to identify novel inhibitors of chikungunya (CHIKV) and dengue (DENY) virus replication, a systematic study with 820 ethyl acetate extracts of madagascan plants was performed in a virus-cell-based assay for ... Pipestelides A-C: Cyclodepsipeptides from the Pacific Marine Sponge Pipestela candelabra [作者：Sorres, J; Martin, MT; Petek, S; Levaique, H; Cresteil, T; Ramos, S; Thoison, O; Debitus, C; Al-Mourabit, A,期刊：Journal of natural products, 页码：759-763 , 文章类型： Article，,卷期：2012年75-4] Pipestelides A-C (2-4) are three new NRPS-PKS hybrid macrolides containing uncommon moieties, isolated from the Pacific marine sponge Pipestela candelabra. Their structures were elucidated on the basis of spectroscopic d... Tyrosyl-DNA Phosphodiesterase 1 Inhibitor from an Anamorphic Fungus [作者：Takagi, M; Ueda, J; Hwang, JH; Hashimoto, J; Izumikawa, M; Murakami, H; Sekido, Y; Shin-ya, K,期刊：Journal of natural products, 页码：764-767 , 文章类型： Article，,卷期：2012年75-4] Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is an enzyme that, Catalyzes hydrolysis of 3'-phosphotyrosl bonds and involved in repair of irreversible topo-isomerase. I (Top1)-DNA covalent complexes Top1 inhabitors which are cu... Hyaladione, an S-Methyl Cyclohexadiene-dione from Hyalangium minutum [作者：Okanya, PW; Mohr, KI; Gerth, K; Steinmetz, H; Huch, V; Jansen, R; Muller, R,期刊：Journal of natural products, 页码：768-770 , 文章类型： Article，,卷期：2012年75-4] A bioassay-guided fractionation of the crude methanol extract of the myxobacterium Hyalangium minutum, strain NOCB-2(T) (DSM 14724(T)), led to the isolation of hyaladione (1), a novel S-methyl cyclohexadiene-dione. The s... Modulation of GABAergic Synaptic Currents and Current Responses by alpha-Thujone and Dihydroumbellulone [作者：Szczot, M; Czyzewska, MM; Appendino, G; Mozrzymas, JW,期刊：Journal of natural products, 页码：622-629 , 文章类型： Article，,卷期：2012年75-4] alpha-Thujone (1a), a constituent of wormwood, has been suspected to cause adverse psychoactive reactions in addicted drinkers of absinthe. While the content of 1a in absinthe is too low for such effects, at higher doses... Asperjinone, a Nor-Neolignan, and Terrein, a Suppressor of ABCG2-Expressing Breast Cancer Cells, from Thermophilic Aspergillus terreus [作者：Liao, WY; Shen, CN; Lin, LH; Yang, YL; Han, HY; Chen, JW; Kuo, SC; Wu, SH; Liaw, CC,期刊：Journal of natural products, 页码：630-635 , 文章类型： Article，,卷期：2012年75-4] Breast cancer cells express ABCG2 transporters, which mediate multidrug resistance. Discovering a novel compound that can suppress ABCG2 expression and restore drug sensitivity could be the key to improving breast cancer... Indiosides G-K: Steroidal Glycosides with Cytotoxic and Anti-inflammatory Activities from Solanum violaceum [作者：Yen, CT; Lee, CL; Chang, FR; Hwang, TL; Yen, HF; Chen, CJ; Chen, SL; Wu, YC,期刊：Journal of natural products, 页码：636-643 , 文章类型： Article，,卷期：2012年75-4] Five new steroidal glycosides (1-5) and nine known compounds were isolated from Solanum violaceum. Indiosides G (1) and H (2) are spirostene saponins with an iso-type F ring, indioside I (3) is a spirostane saponin, and ... Totopotensamides, Polyketide-Cyclic Peptide Hybrids from a Mollusk-Associated Bacterium Streptomyces sp. [作者：Lin, ZJ; Flores, M; Forteza, I; Henriksen, NM; Concepcion, GP; Rosenberg, G; Haygood, MG; Olivera, BM; Light, AR; Cheatham, TE; Schmidt, EW,期刊：Journal of natural products, 页码：644-649 , 文章类型： Article，,卷期：2012年75-4] Two new compounds, the peptide polyketide glycoside totopotensamide A (1) and its aglycone totopotensamide B (2), were isolated from a Streptomyces sp. cultivated from the gastropod mollusk Lienardia totopotens collected... Inhibition of Hepatitis C Virus NS3 Helicase by Manoalide [作者：Salam, KA; Furuta, A; Noda, N; Tsuneda, S; Sekiguchi, Y; Yamashita, A; Moriishi, K; Nakakoshi, M; Tsubuki, M; Tani, H; Tanaka, J; Akimitsu, N,期刊：Journal of natural products, 页码：650-654 , 文章类型： Article，,卷期：2012年75-4] The hepatitis C virus (HCV) causes one of the most prevalent chronic infectious diseases in the world hepatitis C, which ultimately develops into liver cancer through cirrhosis. The NS3 protein of HCV possesses nucleosid... Antineoplastic Agents. 587. Isolation and Structure of 3-Epipancratistatin from Narcissus cv. Ice Follies(1) [作者：Pettit, GR; Tan, R; Bao, GH; Melody, N; Doubek, DL; Gao, S; Chapuis, JC; Williams, L,期刊：Journal of natural products, 页码：771-773 , 文章类型： Article，,卷期：2012年75-4] Bioassay-guided (cancer cell line) separation of an extract prepared from Narcissus cv. Ice Follies (from The Netherlands) led to the isolation of a new Amaryllidaceae isocarbostiryl, 3-epipancratistatin (1b), as well as... Antimicrobial Metabolites from the Paracel Islands Sponge Agelas mauritiana [作者：Yang, F; Hamann, MT; Zou, YK; Zhang, MY; Gong, XB; Xiao, JR; Chen, WS; Lin, HW,期刊：Journal of natural products, 页码：774-778 , 文章类型： Article，,卷期：2012年75-4] Four new alkaloids, (-)-8'-oxo-agelasine D (2), ageloxime B (3), (+)-2-oxo-agelasidine C (4), and 4-bromo-N-(butoxymethyl)-1H-pyrrole-2-carboxamide (5), and the known compound (-)-ageloxime D (1) were isolated from the m... Absolute Configuration and H-1 NMR Characterization of Rosmaridiphenol Diacetate [作者：Munoz, MA; Perez-Hernandez, N; Pertino, MW; Schmeda-Hirschmann, G; Joseph-Nathan, P,期刊：Journal of natural products, 页码：779-783 , 文章类型： Article，,卷期：2012年75-4] The correction of patented structure 1 of rosmaridiphenol, an antioxidant isolated from rosemary, Rosmarinus officinalis, was made recently. The correct structure is proposed as 11,12-dihydroxy-8,11,13-icetexatrien-l-one... Polyhydroxylated Macrolides from Seimatosporium discosioides and Their Effects on the Activation of Peroxisome Proliferator-Activated Receptor Gamma [作者：Hiep, NT; Choi, YH; Kim, N; Hong, SS; Hong, SB; Hwang, BY; Lee, HJ; Lee, SJ; Jang, DS; Lee, D,期刊：Journal of natural products, 页码：784-788 , 文章类型： Article，,卷期：2012年75-4] Two new polyhydroxylated macrolides, seimatopolides A (1) and B (2), were isolated from an EtOAc extract of Seimatosporium discosioides culture medium. The structures of the new compounds were established on the basis of...