- Identical Hik-Rre systems are involved in perception and transduction of salt signals and hyperosmotic signals but regulate the expression of individual genes to different extents in Synechocystis (vol 280, pg 21531, 2005)
[作者:Shumskaya, MA; Paithoonrangsarid, K; Kanesaki, Y; Los, DA; Zinchenko, VV; Tanticharoen, M; Suzuki, I; Murata, N,期刊:Journal of Biological Chemistry, 页码:2269-2269 , 文章类型: Correction,,卷期:2012年287-3]
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- Structural and Mechanistic Insights into Unusual Thiol Disulfide Oxidoreductase
[作者:Garcin, EB; Bornet, O; Elantak, L; Vita, N; Pieulle, L; Guerlesquin, F; Sebban-Kreuzer, C,期刊:Journal of Biological Chemistry, 页码:1688-1697 , 文章类型: Article,,卷期:2012年287-3]
- Cytoplasmic desulfothioredoxin (Dtrx) from the anaerobe Desulfovibrio vulgaris Hildenborough has been identified as a new member of the thiol disulfide oxidoreductase family. The active site of Dtrx contains a particular...
- Mechanism of Clostridium perfringens Enterotoxin Interaction with Claudin-3/-4 Protein Suggests Structural Modifications of the Toxin to Target Specific Claudins
[作者:Veshnyakova, A; Piontek, J; Protze, J; Waziri, N; Heise, I; Krause, G,期刊:Journal of Biological Chemistry, 页码:1698-1708 , 文章类型: Article,,卷期:2012年287-3]
- Claudins (Cld) are essential constituents of tight junctions. Domain I of Clostridium perfringens enterotoxin (cCPE) binds to the second extracellular loop (ECL2) of a subset of claudins, e. g. Cld3/4 and influences tigh...
- The Replication-independent Histone H3-H4 Chaperones HIR, ASF1, and RTT106 Co-operate to Maintain Promoter Fidelity
[作者:Silva, AC; Xu, XM; Kim, HS; Fillingham, J; Kislinger, T; Mennella, TA; Keogh, MC,期刊:Journal of Biological Chemistry, 页码:1709-1718 , 文章类型: Article,,卷期:2012年287-3]
- RNA polymerase II initiates from low complexity sequences so cells must reliably distinguish "real" from "cryptic" promoters and maintain fidelity to the former. Further, this must be performed under a range of condition...
- Identification of Potential Tumor Differentiation Factor (TDF) Receptor from Steroid-responsive and Steroid-resistant Breast Cancer Cells
[作者:Sokolowska, I; Woods, AG; Gawinowicz, MA; Roy, U; Darie, CC,期刊:Journal of Biological Chemistry, 页码:1719-1733 , 文章类型: Article,,卷期:2012年287-3]
- Tumor differentiation factor (TDF) is a recently discovered protein, produced by the pituitary gland and secreted into the bloodstream. TDF and TDF-P1, a 20-amino acid peptide selected from the open reading frame of TDF,...
- Heterogeneous Nuclear Ribonucleoprotein (hnRNP) F Is a Novel Component of Oligodendroglial RNA Transport Granules Contributing to Regulation of Myelin Basic Protein (MBP) Synthesis
[作者:White, R; Gonsior, C; Bauer, NM; Kramer-Albers, EM; Luhmann, HJ; Trotter, J,期刊:Journal of Biological Chemistry, 页码:1742-1754 , 文章类型: Article,,卷期:2012年287-3]
- Myelin basic protein (MBP) is a major component of central nervous system (CNS) myelin. The absence of MBP results in the loss of almost all compact myelin in the CNS. MBP mRNA is sorted into RNA granules that are transp...
- Alternative Splicing Regulates Kv3.1 Polarized Targeting to Adjust Maximal Spiking Frequency
[作者:Gu, YZ; Barry, J; McDougel, R; Terman, D; Gu, C,期刊:Journal of Biological Chemistry, 页码:1755-1769 , 文章类型: Article,,卷期:2012年287-3]
- Synaptic inputs received at dendrites are converted into digital outputs encoded by action potentials generated at the axon initial segment in most neurons. Here, we report that alternative splicing regulates polarized t...
- Insulin-like Growth Factor Binding Protein-4 Differentially Inhibits Growth Factor-induced Angiogenesis
[作者:Contois, LW; Nugent, DP; Caron, JM; Cretu, A; Tweedie, E; Akalu, A; Liebes, L; Friesel, R; Rosen, C; Vary, C; Brooks, PC,期刊:Journal of Biological Chemistry, 页码:1779-1789 , 文章类型: Article,,卷期:2012年287-3]
- An in-depth understanding of the molecular and cellular complexity of angiogenesis continues to advance as new stimulators and inhibitors of blood vessel formation are uncovered. Gaining a more complete understanding of ...
- Crystal Structure of Human beta-Galactosidase STRUCTURAL BASIS OF G(M1) GANGLIOSIDOSIS AND MORQUIO B DISEASES
[作者:Ohto, U; Usui, K; Ochi, T; Yuki, K; Satow, Y; Shimizu, T,期刊:Journal of Biological Chemistry, 页码:1801-1812 , 文章类型: Article,,卷期:2012年287-3]
- G(M1) gangliosidosis and Morquio B are autosomal recessive lysosomal storage diseases associated with a neurodegenerative disorder or dwarfism and skeletal abnormalities, respectively. These diseases are caused by defici...
- Insulin Protects Pancreatic Acinar Cells from Cytosolic Calcium Overload and Inhibition of Plasma Membrane Calcium Pump
[作者:Mankad, P; James, A; Siriwardena, AK; Elliott, AC; Bruce, JIE,期刊:Journal of Biological Chemistry, 页码:1823-1836 , 文章类型: Article,,卷期:2012年287-3]
- Acute pancreatitis is a serious and sometimes fatal inflammatory disease of the pancreas without any reliable treatment or imminent cure. In recent years, impaired metabolism and cytosolic Ca(2+) ([Ca(2+)](i)) overload i...
- Fructose Protects Murine Hepatocytes from Tumor Necrosis Factor-induced Apoptosis by Modulating JNK Signaling
[作者:Speicher, T; Kohler, UA; Chouker, A; Werner, S; Weiland, T; Wendel, A,期刊:Journal of Biological Chemistry, 页码:1837-1846 , 文章类型: Article,,卷期:2012年287-3]
- Fructose-induced hepatic ATP depletion prevents TNF-induced apoptosis, whereas it contrarily enhances CD95-induced hepatocyte apoptosis in vitro and in vivo. By contrast, transformed liver cells are not protected against...
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