- NOX5 in Human Spermatozoa EXPRESSION, FUNCTION, AND REGULATION
[作者：Musset, B; Clark, RA; DeCoursey, TE; Petheo, GL; Geiszt, M; Chen, YM; Cornell, JE; Eddy, CA; Brzyski, RG; El Jamali, A,期刊：Journal of Biological Chemistry, 页码：9376-9388 , 文章类型： Article，,卷期：2012年287-12]
- Physiological and pathological processes in spermatozoa involve the production of reactive oxygen species (ROS), but the identity of the ROS-producing enzyme system(s) remains a matter of speculation. We provide the firs...
- Crystal Structure of Urea Carboxylase Provides Insights into the Carboxyltransfer Reaction
[作者：Fan, C; Chou, CY; Tong, L; Xiang, S,期刊：Journal of Biological Chemistry, 页码：9389-9398 , 文章类型： Article，,卷期：2012年287-12]
- Urea carboxylase (UC) is conserved in many bacteria, algae, and fungi and catalyzes the conversion of urea to allophanate, an essential step in the utilization of urea as a nitrogen source in these organisms. UC belongs ...
- 4-(4-(Dimethylamino)phenyl)-1-methylpyridinium (APP(+)) Is a Fluorescent Substrate for the Human Serotonin Transporter
[作者：Solis, E; Zdravkovic, I; Tomlinson, ID; Noskov, SY; Rosenthal, SJ; De Felice, LJ,期刊：Journal of Biological Chemistry, 页码：8852-8863 , 文章类型： Article，,卷期：2012年287-12]
- Monoamine transporters terminate synaptic neurotransmission and are molecular targets for antidepressants and psychostimulants. Fluorescent reporters can monitor real-time transport and are amenable for high-throughput s...
- Unique Disulfide Bonds in Epidermal Growth Factor (EGF) Domains of beta 3 Affect Structure and Function of alpha IIb beta 3 and alpha v beta 3 Integrins in Different Manner
[作者：Mor-Cohen, R; Rosenberg, N; Einav, Y; Zelzion, E; Landau, M; Mansour, W; Averbukh, Y; Seligsohn, U,期刊：Journal of Biological Chemistry, 页码：8879-8891 , 文章类型： Article，,卷期：2012年287-12]
- The beta 3 subunit of alpha IIb beta 3 and alpha v beta 3 integrins contains four epidermal growth factor (EGF)-like domains. Each domain harbors four disulfide bonds of which one is unique for integrins. We previously d...
- Lipocalin-type Prostaglandin D-2 Synthase Protein Regulates Glial Cell Migration and Morphology through Myristoylated Alanine-rich C-Kinase Substrate PROSTAGLANDIN D-2-INDEPENDENT EFFECTS
[作者：Lee, S; Jang, E; Kim, JH; Kim, JH; Lee, WH; Suk, K,期刊：Journal of Biological Chemistry, 页码：9414-9428 , 文章类型： Article，,卷期：2012年287-12]
- Prostaglandin D synthase (PGDS) is responsible for the conversion of PGH(2) to PGD(2). Two distinct types of PGDS have been identified: hematopoietic-type PGDS (H-PGDS) and lipocalin-type PGDS (L-PGDS). L-PGDS acts as bo...
- Constitutive Clathrin-mediated Endocytosis of CTLA-4 Persists during T Cell Activation
[作者：Qureshi, OS; Kaur, S; Hou, TZ; Jeffery, LE; Poulter, NS; Briggs, Z; Kenefeck, R; Willox, AK; Royle, SJ; Rappoport, JZ; Sansom, DM,期刊：Journal of Biological Chemistry, 页码：9429-9440 , 文章类型： Article，,卷期：2012年287-12]
- CTLA-4 is one of the most important negative regulators of the T cell immune response. However, the subcellular distribution of CTLA-4 is unusual for a receptor that interacts with cell surface transmembrane ligands in t...
- Solution Structure Analysis of Cytoplasmic Domain of Podocyte Protein Neph1 Using Small/Wide Angle X-ray Scattering (SWAXS)
[作者：Mallik, L; Arif, E; Sharma, P; Rathore, YS; Wong, HN; Holzman, LB; Ashish; Nihalani, D,期刊：Journal of Biological Chemistry, 页码：9441-9453 , 文章类型： Article，,卷期：2012年287-12]
- Neph1 is present in podocytes, where it plays a critical role in maintaining the filtration function of the glomerulus, in part through signaling events mediated by its cytoplasmic domain that are involved in actin cytos...
- Mitochondrial Membrane Complex That Contains Proteins Necessary for tRNA Import in Trypanosoma brucei
[作者：Seidman, D; Johnson, D; Gerbasi, V; Golden, D; Orlando, R; Hajduk, S,期刊：Journal of Biological Chemistry, 页码：8892-8903 , 文章类型： Article，,卷期：2012年287-12]
- The mitochondrial genome of Trypanosoma brucei does not contain genes encoding tRNAs; instead this protozoan parasite must import nuclear-encoded tRNAs from the cytosol for mitochondrial translation. Previously, it has b...
- Unique Iron Coordination in Iron-chelating Molecule Vibriobactin Helps Vibrio cholerae Evade Mammalian Siderocalin-mediated Immune Response
[作者：Li, N; Zhang, CG; Li, BQ; Liu, XH; Huang, Y; Xu, SJ; Gu, LC,期刊：Journal of Biological Chemistry, 页码：8912-8919 , 文章类型： Article，,卷期：2012年287-12]
- Iron is essential for the survival of almost all bacteria. Vibrio cholerae acquires iron through the secretion of a catecholate siderophore called vibriobactin. At present, how vibriobactin chelates ferric ion remains co...
- Crystal Structure of Interleukin-21 Receptor (IL-21R) Bound to IL-21 Reveals That Sugar Chain Interacting with WSXWS Motif Is Integral Part of IL-21R
[作者：Hamming, OJ; Kang, LS; Svensson, A; Karlsen, JL; Rahbek-Nielsen, H; Paludan, SR; Hjorth, SA; Bondensgaard, K; Hartmann, R,期刊：Journal of Biological Chemistry, 页码：9454-9460 , 文章类型： Article，,卷期：2012年287-12]
- IL-21 is a class I cytokine that exerts pleiotropic effects on both innate and adaptive immune responses. It signals through a heterodimeric receptor complex consisting of the IL-21 receptor (IL-21R) and the common gamma...
- Identification of a Small Molecule That Modulates Platelet Glycoprotein Ib-von Willebrand Factor Interaction
[作者：Broos, K; Trekels, M; Jose, RA; Demeulemeester, J; Vandenbulcke, A; Vandeputte, N; Venken, T; Egle, B; De Borggraeve, WM; Deckmyn, H; De Maeyer, M,期刊：Journal of Biological Chemistry, 页码：9461-9472 , 文章类型： Article，,卷期：2012年287-12]
- The von Willebrand factor (VWF) A1-glycoprotein (GP) Ib alpha interaction is of major importance during thrombosis mainly at sites of high shear stress. Inhibitors of this interaction prevent platelet-dependent thrombus ...
- Protein Kinase D Regulates RhoA Activity via Rhotekin Phosphorylation
[作者：Pusapati, GV; Eiseler, T; Rykx, A; Vandoninck, S; Derua, R; Waelkens, E; Van Lint, J; von Wichert, G; Seufferlein, T,期刊：Journal of Biological Chemistry, 页码：9473-9483 , 文章类型： Article，,卷期：2012年287-12]
- The members of the protein kinase D (PKD) family of serine/threonine kinases are major targets for tumor-promoting phorbol esters, G protein-coupled receptors, and activated protein kinase C isoforms (PKCs). The expandin...
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