- A Novel Cardiomyocyte-enriched MicroRNA, miR-378, Targets Insulin-like Growth Factor 1 Receptor IMPLICATIONS IN POSTNATAL CARDIAC REMODELING AND CELL SURVIVAL
[作者:Knezevic, I; Patel, A; Sundaresan, NR; Gupta, MP; Solaro, RJ; Nagalingam, RS; Gupta, M,期刊:Journal of Biological Chemistry, 页码:12913-12926 , 文章类型: Article,,卷期:2012年287-16]
- Postnatal cardiac remodeling is characterized by a marked decrease in the insulin-like growth factor 1 (IGF1) and IGF1 receptor (IGF1R) expression. The underlying mechanism remains unexplored. This study examined the rol...
- MarR-type Transcriptional Regulator ChlR Activates Expression of Tetrapyrrole Biosynthesis Genes in Response to Low-oxygen Conditions in Cyanobacteria
[作者:Aoki, R; Takeda, T; Omata, T; Ihara, K; Fujita, Y,期刊:Journal of Biological Chemistry, 页码:13500-13507 , 文章类型: Article,,卷期:2012年287-16]
- Oxygen is required for three enzyme reactions in chlorophyll and bilin biosynthesis pathways: coproporphyrinogen III oxidase (HemF), heme oxygenase (HO1), and Mg-protoporphyrin IX monomethylester cyclase (ChlA(I)). The c...
- Peroxisome Proliferator-activated Receptor beta/delta Induces Myogenesis by Modulating Myostatin Activity
[作者:Bonala, S; Lokireddy, S; Arigela, H; Teng, S; Wahli, W; Sharma, M; McFarlane, C; Kambadur, R,期刊:Journal of Biological Chemistry, 页码:12935-12951 , 文章类型: Article,,卷期:2012年287-16]
- Classically, peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) function was thought to be restricted to enhancing adipocyte differentiation and development of adipose-like cells from other lineages....
- Identification and Profiling of Novel alpha(1A)-Adrenoceptor-CXC Chemokine Receptor 2 Heteromer
[作者:Mustafa, S; See, HB; Seeber, RM; Armstrong, SP; White, CW; Ventura, S; Ayoub, MA; Pfleger, KDG,期刊:Journal of Biological Chemistry, 页码:12952-12965 , 文章类型: Article,,卷期:2012年287-16]
- We have provided the first evidence for specific heteromerization between the alpha(1A)-adrenoceptor (alpha(1A)AR) and CXC chemokine receptor 2 (CXCR2) in live cells. alpha(1A)AR and CXCR2 are both expressed in areas suc...
- CHFR Protein Regulates Mitotic Checkpoint by Targeting PARP-1 Protein for Ubiquitination and Degradation
[作者:Kashima, L; Idogawa, M; Mita, H; Shitashige, M; Yamada, T; Ogi, K; Suzuki, H; Toyota, M; Ariga, H; Sasaki, Y; Tokino, T,期刊:Journal of Biological Chemistry, 页码:12975-12984 , 文章类型: Article,,卷期:2012年287-16]
- The mitotic checkpoint gene CHFR (checkpoint with fork-head-associated (FHA) and RING finger domains) is silenced by promoter hypermethylation or mutated in various human cancers, suggesting that CHFR is an important tum...
- Caspar-like Gene Depletion Reduces Leishmania Infection in Sand Fly Host Lutzomyia longipalpis
[作者:Telleria, EL; Sant'Anna, MRV; Ortigao-Farias, JR; Pitaluga, AN; Dillon, VM; Bates, PA; Traub-Cseko, YM; Dillon, RJ,期刊:Journal of Biological Chemistry, 页码:12985-12993 , 文章类型: Article,,卷期:2012年287-16]
- Female phlebotomine sand flies Lutzomyia longipalpis naturally harbor populations of the medically important Leishmania infantum (syn. Leishmania chagasi) parasite in the gut, but the extent to which the parasite interac...
- JMJD5, a Jumonji C (JmjC) Domain-containing Protein, Negatively Regulates Osteoclastogenesis by Facilitating NFATc1 Protein Degradation
[作者:Youn, MY; Yokoyama, A; Fujiyama-Nakamura, S; Ohtake, F; Minehata, K; Yasuda, H; Suzuki, T; Kato, S; Imai, Y,期刊:Journal of Biological Chemistry, 页码:12994-13004 , 文章类型: Article,,卷期:2012年287-16]
- Osteoclastogenesis is a highly regulated process governed by diverse classes of regulators. Among them, nuclear factor of activated T-cells calcineurin-dependent 1 (NFATc1) is the primary osteoclastogenic transcription f...
- The Amotl2 Gene Inhibits Wnt/beta-Catenin Signaling and Regulates Embryonic Development in Zebrafish
[作者:Li, ZQ; Wang, YQ; Zhang, M; Xu, PF; Huang, HZ; Wu, D; Meng, AM,期刊:Journal of Biological Chemistry, 页码:13005-13015 , 文章类型: Article,,卷期:2012年287-16]
- The Motin family proteins can regulate cell polarity, cell mobility, and proliferation during embryonic development by controlling distinct signaling pathways. In this study, we demonstrate that amotl2 knockdown in zebra...
- Ferritin Protein Nanocage Ion Channels GATING BY N-TERMINAL EXTENSIONS
[作者:Tosha, T; Behera, RK; Ng, HL; Bhattasali, O; Alber, T; Theil, EC,期刊:Journal of Biological Chemistry, 页码:13016-13025 , 文章类型: Article,,卷期:2012年287-16]
- Ferritin protein nanocages, self-assembled from four-alpha-helix bundle subunits, use Fe2+ and oxygen to synthesize encapsulated, ferric oxide minerals. Ferritin minerals are iron concentrates stored for cell growth. Fer...
- Sequence-specific Recruitment of Heterochromatin Protein 1 via Interaction with Kruppel-like Factor 11, a Human Transcription Factor Involved in Tumor Suppression and Metabolic Diseases
[作者:Lomberk, G; Mathison, AJ; Grzenda, A; Seo, S; Demars, CJ; Rizvi, S; Bonilla-Velez, J; Calvo, E; Fernandez-Zapico, ME; Iovanna, J; Buttar, NS; Urrutia, R,期刊:Journal of Biological Chemistry, 页码:13026-13039 , 文章类型: Article,,卷期:2012年287-16]
- Heterochromatin protein 1 (HP1) proteins are "gatekeepers" of epigenetic gene silencing that is mediated by lysine 9 of histone H3 methylation (H3K9me). Current knowledge supports a paradigm whereby HP1 proteins achieve ...
- DNA Lesion Alters Global Conformational Dynamics of Y-family DNA Polymerase during Catalysis
[作者:Maxwell, BA; Xu, CL; Suo, ZC,期刊:Journal of Biological Chemistry, 页码:13040-13047 , 文章类型: Article,,卷期:2012年287-16]
- A major product of oxidative damage to DNA, 8-oxo-7,8-dihydro-2'-deoxyguanine (8-oxoG), can lead to genomic mutations if it is bypassed unfaithfully by DNA polymerases in vivo. However, our pre-steady-state kinetic studi...
- Mutant profilin suppresses mutant actin-dependent mitochondrial phenotype in Saccharomyces cerevisiae (vol 286, pg 41745, 2011)
[作者:Wen, KK; McKane, M; Stokasimov, E; Rubenstein, PA,期刊:Journal of Biological Chemistry, 页码:13048-13048 , 文章类型: Correction,,卷期:2012年287-16]
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- Delta Np63 alpha protein triggers epithelial-mesenchymal transition and confers stem cell properties in normal human keratinocytes (vol 286, pg 38757, 2011)
[作者:Oh, JE; Kim, RH; Shin, KH; Park, NH; Kang, MK,期刊:Journal of Biological Chemistry, 页码:13049-13049 , 文章类型: Correction,,卷期:2012年287-16]
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- Identification of a molecular activator for insulin receptor with potent anti-diabetic effects (vol 286, pg 37379, 2011)
[作者:He, KY; Chan, CB; Liu, X; Jia, YH; Luo, HBR; France, SA; Liu, Y; Wilson, WD; Ye, KQ,期刊:Journal of Biological Chemistry, 页码:13050-13050 , 文章类型: Correction,,卷期:2012年287-16]
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