- Treatment, risk factors, and outcome of adults with relapsed AML after reduced intensity conditioning for allogeneic stem cell transplantation
[作者:Schmid, C; Labopin, M; Nagler, A; Niederwieser, D; Castagna, L; Tabrizi, R; Stadler, M; Kuball, J; Cornelissen, J; Vorlicek, J; Socie, G; Falda, M; Vindelov, L; Ljungman, P; Jackson, G; Kroger, N; Rank, A; Polge, E; Rocha, V; Mohty, M,期刊:Blood, 页码:1599-1606 , 文章类型: Article,,卷期:2012年119-6]
- Because information on management and outcome of AML relapse after allogeneic hematopoietic stem cell transplantation (HSCT) with reduced intensity conditioning (RIC) is scarce, a retrospective registry study was perform...
- MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A
[作者:Urbich, C; Kaluza, D; Fromel, T; Knau, A; Bennewitz, K; Boon, RA; Bonauer, A; Doebele, C; Boeckel, JN; Hergenreider, E; Zeiher, AM; Kroll, J; Fleming, I; Dimmeler, S,期刊:Blood, 页码:1607-1616 , 文章类型: Article,,卷期:2012年119-6]
- MicroRNAs (miRs) are small RNAs that regulate gene expression at the posttranscriptional level. miR-27 is expressed in endothelial cells, but the specific functions of miR-27b and its family member miR27a are largely unk...
- NF-Y is necessary for hematopoietic stem cell proliferation and survival
[作者:Bungartz, G; Land, H; Scadden, DT; Emerson, SG,期刊:Blood, 页码:1380-1389 , 文章类型: Article,,卷期:2012年119-6]
- HSC function depends on the tight control of proliferation and the balance between self-renewal and differentiation. Here, we report that the trimeric transcription factor NF-Y is critical for the survival of cycling, bu...
- Functional heterogeneity of human effector CD8(+) T cells
[作者:Takata, H; Naruto, T; Takiguchi, M,期刊:Blood, 页码:1390-1398 , 文章类型: Article,,卷期:2012年119-6]
- Effector CD8(+) T cells are believed to be terminally differentiated cells having cytotoxic activity and the ability to produce effector cytokines such as INF-gamma and TNF-alpha. We investigated the difference between C...
- IFN-alpha enhances cross-presentation in human dendritic cells by modulating antigen survival, endocytic routing, and processing
[作者:Spadaro, F; Lapenta, C; Donati, S; Abalsamo, L; Barnaba, V; Belardelli, F; Santini, SM; Ferrantini, M,期刊:Blood, 页码:1407-1417 , 文章类型: Article,,卷期:2012年119-6]
- Cross-presentation allows antigen-presenting cells to present exogenous antigens to CD8(+) T cells, playing an essential role in controlling infections and tumor development. IFN-alpha induces the rapid differentiation o...
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