- Chemokine Receptor CCR1 Disruption Limits Renal Damage in a Murine Model of Hemolytic Uremic Syndrome
[作者:Ramos, MV; Auvynet, C; Poupel, L; Rodero, M; Mejias, MP; Panek, CA; Vanzulli, S; Combadiere, C; Palermo, M,期刊:American Journal of Pathology, 页码:1040-1048 , 文章类型: Article,,卷期:2012年180-3]
- Shiga toxin (Stx)-producing Escherichia coli is the main etiological agent that causes hemolytic uremic syndrome (HUS), a microangiopathic disease characterized by hemolytic anemia, thrombocytopenia, and acute renal fail...
- p47(Phox) Directs Murine Macrophage Cell Fate Decisions
[作者:Yi, L; Liu, Q; Orandle, MS; Sadiq-Ali, S; Koontz, SM; Choi, U; Torres-Velez, FJ; Jackson, SH,期刊:American Journal of Pathology, 页码:1049-1058 , 文章类型: Article,,卷期:2012年180-3]
- Macrophage differentiation and function are pivotal for cell survival from infection and involve the processing of microenvironmental signals that determine macrophage cell fate decisions to establish appropriate inflamm...
- Glucocorticoid-Induced Tumor Necrosis Factor Receptor Family-Related Protein Exacerbates Collagen-Induced Arthritis by Enhancing the Expansion of Th17 Cells
[作者:Wang, SJ; Shi, Y; Yang, M; Ma, J; Tian, J; Chen, JG; Mao, CM; Jiao, ZJ; Ko, KH; Baidoo, SE; Xu, HX; Hua, ZC; Lu, LW,期刊:American Journal of Pathology, 页码:1059-1067 , 文章类型: Article,,卷期:2012年180-3]
- kin-17 production. Taken together, the results from this study have revealed a new function of GITRL in exacerbating autoimmune arthritis via the enhancement of the expansion of Th17 cells. (Am J Pathol 2012, 180:1059-10...
- Interspecies Comparison of Human and Murine Scleroderma Reveals IL-13 and CCL2 as Disease Subset-Specific Targets
[作者:Greenblatt, MB; Sargent, JL; Farina, G; Tsang, K; Lafyatis, R; Glimcher, LH; Whitfield, ML; Aliprantis, AO,期刊:American Journal of Pathology, 页码:1080-1094 , 文章类型: Article,,卷期:2012年180-3]
- Development of personalized treatment regimens is hampered by lack of insight into how individual animal models reflect subsets of human disease, and autoimmune and inflammatory conditions have proven resistant to such e...
- Neural Stem Cell Depletion and CNS Developmental Defects After Enteroviral Infection
[作者:Ruller, CM; Tabor-Godwin, JM; Deren, DA; Robinson, SM; Maciejewski, S; Gluhm, S; Gilbert, PE; An, NL; Gude, NA; Sussman, MA; Whitton, JL; Feuer, R,期刊:American Journal of Pathology, 页码:1107-1120 , 文章类型: Article,,卷期:2012年180-3]
- Coxsackieviruses are significant human pathogens causing myocarditis, meningitis, and encephalitis. We previously demonstrated the ability of coxsackievirus B3 (CVB3) to persist within the neonatal central nervous system...
- Growth Defects and Impaired Cognitive-Behavioral Abilities in Mice with Knockout for Eif4h, a Gene Located in the Mouse Homolog of the Williams-Beuren Syndrome Critical Region
[作者:Capossela, S; Muzio, L; Bertolo, A; Bianchi, V; Dati, G; Chaabane, L; Godi, C; Politi, LS; Biffo, S; D'Adamo, P; Mallamaci, A; Pannese, M,期刊:American Journal of Pathology, 页码:1121-1135 , 文章类型: Article,,卷期:2012年180-3]
- Protein synthesis is a tightly regulated, energy-consuming process. The control of mRNA translation into protein is fundamentally important for the fine-tuning of gene expression; additionally, precise translational cont...
- Platelet-Derived Growth Factor C Deficiency in C57BL/6 Mice Leads to Abnormal Cerebral Vascularization, Loss of Neuroependymal Integrity, and Ventricular Abnormalities
[作者:Fredriksson, L; Nilsson, I; Su, EMJ; Andrae, J; Ding, H; Betsholtz, C; Eriksson, U; Lawrence, DA,期刊:American Journal of Pathology, 页码:1136-1144 , 文章类型: Article,,卷期:2012年180-3]
- Platelet-derived growth factors (PDGFs) and their tyrosine kinase receptors (PDGFRs) are known to play important roles during development of the lungs, central nervous system (CNS), and skeleton and in several diseases. ...
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