- ApoE-Directed Therapeutics Rapidly Clear beta-Amyloid and Reverse Deficits in AD Mouse Models
[作者:Cramer, PE; Cirrito, JR; Wesson, DW; Lee, CYD; Karlo, JC; Zinn, AE; Casali, BT; Restivo, JL; Goebel, WD; James, MJ; Brunden, KR; Wilson, DA; Landreth, GE,期刊:Science, 页码:1503-1506 , 文章类型: Article,,卷期:2012年335-6075]
- Alzheimer's disease (AD) is associated with impaired clearance of beta-amyloid (A beta) from the brain, a process normally facilitated by apolipoprotein E (apoE). ApoE expression is transcriptionally induced through the ...
- MARF1 Regulates Essential Oogenic Processes in Mice
[作者:Su, YQ; Sugiura, K; Sun, FY; Pendola, JK; Cox, GA; Handel, MA; Schimenti, JC; Eppig, JJ,期刊:Science, 页码:1496-1499 , 文章类型: Article,,卷期:2012年335-6075]
- Development of fertilization-competent oocytes depends on integrated processes controlling meiosis, cytoplasmic development, and maintenance of genomic integrity. We show that meiosis arrest female 1 (MARF1) is required ...
- Evolutionary Conservation of Species' Roles in Food Webs
[作者:Stouffer, DB; Sales-Pardo, M; Sirer, MI; Bascompte, J,期刊:Science, 页码:1489-1492 , 文章类型: Article,,卷期:2012年335-6075]
- Studies of ecological networks (the web of interactions between species in a community) demonstrate an intricate link between a community's structure and its long-term viability. It remains unclear, however, how much a c...
- Experimental Realization of a Magnetic Cloak
[作者:Gomory, F; Solovyov, M; Souc, J; Navau, C; Prat-Camps, J; Sanchez, A,期刊:Science, 页码:1466-1468 , 文章类型: Article,,卷期:2012年335-6075]
- Invisibility to electromagnetic fields has become an exciting theoretical possibility. However, the experimental realization of electromagnetic cloaks has only been achieved starting from simplified approaches (for insta...
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