- Cardiac Structural and Functional Alterations in Infants and Children With Biliary Atresia, Listed for Liver Transplantation
[作者:Desai, MS; Zainuer, S; Kennedy, C; Kearney, D; Goss, J; Karpen, SJ,期刊:Gastroenterology, 页码:1264-U690 , 文章类型: Article,,卷期:2011年141-4]
- BACKGROUND & AIMS: Cirrhotic liver diseases are associated with abnormalities in cardiac geometry and function in adults (cirrhotic cardiomyopathy) but rarely explored in cirrhotic infants or children. We proposed that f...
- PAR2 Promotes Vaccine-Induced Protection Against Helicobacter Infection in Mice
[作者:Velin, D; Narayan, S; Bernasconi, E; Busso, N; Ramelli, G; Maillard, MH; Bachmann, D; Pythoud, C; Bouzourene, H; Michetti, P; So, A,期刊:Gastroenterology, 页码:1273-U701 , 文章类型: Article,,卷期:2011年141-4]
- BACKGROUND & AIMS: Protective immunization limits Helicobacter infection of mice by undetermined mechanisms. Protease-activated receptor 2 (PAR2) signaling is believed to regulate immune and inflammatory responses. We in...
- Extensive Pancreas Regeneration Following Acinar-Specific Disruption of Xbp1 in Mice
[作者:Hess, DA; Humphrey, SE; Ishibashi, J; Damsz, B; Lee, AH; Glimcher, LH; Konieczny, SF,期刊:Gastroenterology, 页码:1463-1472 , 文章类型: Article,,卷期:2011年141-4]
- BACKGROUND & AIMS: Progression of diseases of the exocrine pancreas, which include pancreatitis and cancer, is associated with increased levels of cell stress. Pancreatic acinar cells are involved in development of these...
- Myeloid, but Not Pancreatic, RelA/p65 Is Required for Fibrosis in a Mouse Model of Chronic Pancreatitis
[作者:Treiber, M; Neuhofer, P; Anetsberger, E; Einwachter, H; Lesina, M; Rickmann, M; Liang, S; Kehl, T; Nakhai, H; Schmid, RM; Algul, H,期刊:Gastroenterology, 页码:1473-U477 , 文章类型: Article,,卷期:2011年141-4]
- BACKGROUND & AIMS: Little is known about how transcription factors might regulate pathogenesis of chronic pancreatitis (CP). We analyzed the in vivo role of RelA/p65, a component of the transcription factor nuclear facto...
- Retinoic Acid-Induced Pancreatic Stellate Cell Quiescence Reduces Paracrine Wnt-beta-Catenin Signaling to Slow Tumor Progression
[作者:Froeling, FEM; Feig, C; Chelala, C; Dobson, R; Mein, CE; Tuveson, DA; Clevers, H; Hart, IR; Kocher, HM,期刊:Gastroenterology, 页码:1486-U503 , 文章类型: Article,,卷期:2011年141-4]
- BACKGROUND & AIMS: Patients with pancreatic ductal adenocarcinoma are deficient in vitamin A, resulting in activation of pancreatic stellate cells (PSCs). We investigated whether restoration of retinol to PSCs restores t...
- The Future Role of the Gastroenterologist in Digestive Oncology: An International Perspective
[作者:Winawer, SJ; Pasricha, PJ; Schmiegel, W; Sinicrope, FA; Sung, J; Seufferlein, T; Kassem, AM; Malekzadeh, R; Kurtz, RC; Classen, M; Tytgat, GN,期刊:Gastroenterology, 页码:E13-E21 , 文章类型: Review,,卷期:2011年141-4]
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- Matrix Metalloproteinase-9 Inhibition Reduces Inflammation and Improves Motility in Murine Models of Postoperative Ileus
[作者:Moore, BA; Manthey, CL; Johnson, DL; Bauer, AJ,期刊:Gastroenterology, 页码:1283-U715 , 文章类型: Article,,卷期:2011年141-4]
- BACKGROUND & AIMS: Matrix metalloproteinase (MMP)-9, a member of the gelatinase family of MMPs, mediates leukocyte migration during inflammation. Inflammation contributes to development of postoperative ileus (POI), whic...
- Kruppel-Like Factor 5 Is Important for Maintenance of Crypt Architecture and Barrier Function in Mouse Intestine
[作者:McConnell, BB; Kim, SS; Yu, K; Ghaleb, AM; Takeda, N; Manabe, I; Nusrat, A; Nagai, R; Yang, VW,期刊:Gastroenterology, 页码:1302-U745 , 文章类型: Article,,卷期:2011年141-4]
- BACKGROUND & AIMS: Kruppel-like factor 5 (KLF5) is transcription factor that is expressed by dividing epithelial cells of the intestinal epithelium. KLF5 promotes proliferation in vitro and in vivo and is induced by mito...
- Proton Pump Inhibitors Exacerbate NSAID-Induced Small Intestinal Injury by Inducing Dysbiosis
[作者:Wallace, JL; Syer, S; Denou, E; de Palma, G; Vong, L; McKnight, W; Jury, J; Bolla, M; Bercik, P; Collins, SM; Verdu, E; Ongini, E,期刊:Gastroenterology, 页码:1314-U759 , 文章类型: Article,,卷期:2011年141-4]
- BACKGROUND & AIMS: Proton pump inhibitors (PPIs) and nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used classes of drugs, with the former frequently coprescribed to reduce gastroduodenal injur...
- The PepT1-NOD2 Signaling Pathway Aggravates Induced Colitis in Mice
[作者:Dalmasso, G; Hang, TTN; Ingersoll, SA; Ayyadurai, S; Laroui, H; Charania, MA; Yan, YT; Sitaraman, SV; Merlin, D,期刊:Gastroenterology, 页码:1334-1345 , 文章类型: Article,,卷期:2011年141-4]
- BACKGROUND & AIMS: The human di/tripeptide transporter human intestinal H-coupled oligonucleotide transporter (hPepT1) is abnormally expressed in colons of patients with inflammatory bowel disease, although its exact rol...
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